{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T06:58:07Z","timestamp":1793948287150,"version":"4.8.0"},"reference-count":60,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T00:00:00Z","timestamp":1740441600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Objective<\/jats:title>\n<jats:p>The scarcity of literature necessitates further research to differentiate between acute and chronic painful temporomandibular disorders (TMDs). This study compared pain characteristics, oral behaviors, jaw function, and psychosocial distress between TMD patients with acute and chronic pain, examined correlations among variables, and identified factors associated with chronic pain-related TMDs (PT).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Anonymized data were gathered from consecutive patients seeking TMD treatment at a university-based oral medicine clinic. Axis I diagnoses were made using the Diagnostic Criteria for TMDs, and patients with PT were categorized into acute (AP) and chronic pain (CP) groups. Axis II assessments were performed, evaluating pain characteristics, oral behaviors, jaw functional limitation, somatic symptoms, depression, and anxiety. Statistical analysis utilized chi-square\/non-parametric tests and logistic regression (\u03b1 =\u2009 0.05).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Among the 488 PT patients, 34.6% experienced AP and 65.4% had CP. Significant differences were observed in pain intensity, interference, disability, jaw overuse behavior, functional limitation, somatic symptom burden, depression, and anxiety. (CP&gt;\u2009 AP). Moderate-to-strong correlations were found in both the AP (<jats:italic>r<\/jats:italic><jats:sub><jats:italic>s<\/jats:italic><\/jats:sub> =\u2009 0.43\u20130.83) and CP (<jats:italic>r<\/jats:italic><jats:sub><jats:italic>s<\/jats:italic><\/jats:sub> =\u2009 0.46\u20130.87) groups, although the specific relationships between pain, behavioral, and psychosocial factors differed somewhat. The multivariate regression model revealed that only pain intensity (OR =\u2009 1.01) and oral behaviors (OR =\u2009 1.06) significantly increased the odds of chronic PT.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Chronic pain was more prevalent in PT patients and associated with greater severity in pain, behavioral, and psychosocial variables. Pain intensity and oral behaviors were linked to an increased likelihood of chronic pain.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0318946","type":"journal-article","created":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T18:51:03Z","timestamp":1740509463000},"page":"e0318946","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":10,"title":["Comparative analysis of acute and chronic painful temporomandibular disorders: Insights into pain, behavioral, and psychosocial features"],"prefix":"10.1371","volume":"20","author":[{"given":"Adrian Ujin","family":"Yap","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Hwan","family":"Jo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunghae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byeong-min","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0625-7021","authenticated-orcid":true,"given":"Ji Woon","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,2,25]]},"reference":[{"issue":"10","key":"pone.0318946.ref001","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1111\/joor.13779","article-title":"Prevalence of temporomandibular disorders and their associated factors in Confucian heritage cultures: A systematic review and meta-analysis","volume":"51","author":"AU Yap","year":"2024","journal-title":"J Oral Rehabil"},{"issue":"4","key":"pone.0318946.ref002","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/s00702-020-02157-3","article-title":"Chronic orofacial pain","volume":"127","author":"S Ananthan","year":"2020","journal-title":"J Neural Transm"},{"issue":"8","key":"pone.0318946.ref003","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1097\/j.pain.0000000000001872","article-title":"Increasing gender differences in the prevalence and chronification of orofacial pain in the population","volume":"161","author":"B H\u00e4ggman-Henrikson","year":"2020","journal-title":"Pain"},{"issue":"1","key":"pone.0318946.ref004","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/j.pain.0000000000001384","article-title":"Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11)","volume":"160","author":"R-D Treede","year":"2019","journal-title":"Pain"},{"key":"pone.0318946.ref005","doi-asserted-by":"crossref","first-page":"e076227","DOI":"10.1136\/bmj-2023-076227","article-title":"Management of chronic pain associated with temporomandibular disorders: a clinical practice guideline","volume":"383","author":"JW Busse","year":"2023","journal-title":"BMJ"},{"issue":"7","key":"pone.0318946.ref006","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1177\/0333102416686302","article-title":"Temporomandibular disorders: Old ideas and new concepts","volume":"37","author":"T List","year":"2017","journal-title":"Cephalalgia"},{"issue":"2","key":"pone.0318946.ref007","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/joor.13606","article-title":"Correlates of jaw functional limitation, somatization and psychological distress among different temporomandibular disorder diagnostic subtypes","volume":"51","author":"AU Yap","year":"2024","journal-title":"J Oral Rehabil"},{"issue":"1","key":"pone.0318946.ref008","doi-asserted-by":"crossref","first-page":"6","DOI":"10.11607\/jop.1151","article-title":"International RDC\/TMD consortium network, international association for dental research. 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