{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T18:10:09Z","timestamp":1744913409610,"version":"3.40.4"},"reference-count":42,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009193","name":"Marsden Fund","doi-asserted-by":"publisher","award":["19-UOW-035"],"award-info":[{"award-number":["19-UOW-035"]}],"id":[{"id":"10.13039\/501100009193","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Accurately predicting how the global environment will change under continued CO<jats:sub>2<\/jats:sub> and temperature increases is currently a critical issue. Predictions are dependent on global models that represent this complex system of natural and anthropogenic inputs, responses, and feedback loops. These models must include accurate descriptions of complex biological processes such as photosynthesis, which is currently responsible for the removal of 123 petagrams of atmospheric carbon annually. Here, we develop a simplified approach to model the effect of concurrent changes in temperature and CO<jats:sub>2<\/jats:sub> concentrations on the rate of C<jats:sub>3<\/jats:sub> carbon fixation. The model simplifies the temperature response of the CO<jats:sub>2<\/jats:sub> fixation pathway into a three-parameter curve (as modelled by macromolecular rate theory, MMRT), which incorporates the limitations of RuBisCO kinetics, and CO<jats:sub>2<\/jats:sub> and O<jats:sub>2<\/jats:sub> solubility as simple system constraints. This framework fully accounts for the temperature and CO<jats:sub>2<\/jats:sub> dependence of CO<jats:sub>2<\/jats:sub> fixation rates in sweet potato (<jats:italic>Ipomoea batatas<\/jats:italic>) leaves with just three parameters, in combination with defined biophysical constraints.<\/jats:p>","DOI":"10.1371\/journal.pone.0319324","type":"journal-article","created":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T17:31:19Z","timestamp":1744911079000},"page":"e0319324","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["A minimal biophysical model for the temperature dependence of CO2 fixation rates based on macromolecular rate theory"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7417-7296","authenticated-orcid":true,"given":"Erica J.","family":"Prentice","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret M.","family":"Barbour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vickery L.","family":"Arcus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2025,4,17]]},"reference":[{"key":"pone.0319324.ref001","article-title":"Climate Change 2013: The Physical Science Basis","volume-title":"Contribution of Working Group I to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change","author":"P Ciais","year":"2013"},{"issue":"2","key":"pone.0319324.ref002","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s00468-016-1496-0","article-title":"Characterization of photosynthetic acclimation in Phoenix dactylifera by a modified Arrhenius equation originally developed for leaf respiration","volume":"31","author":"J Kruse","year":"2017","journal-title":"Trees"},{"issue":"9","key":"pone.0319324.ref003","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1111\/j.1365-3040.2007.01682.x","article-title":"The temperature response of C3 and C4 photosynthesis","volume":"30","author":"RF Sage","year":"2007","journal-title":"Plant Cell Environ"},{"issue":"9","key":"pone.0319324.ref004","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1046\/j.1365-3040.2002.00891.x","article-title":"Temperature response of parameters of a biochemically based model of photosynthesis. 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3","key":"pone.0319324.ref028","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1042\/bj3301087","article-title":"The effects of temperature on the kinetics and stability of mesophilic and thermophilic 3-phosphoglycerate kinases","volume":"330","author":"TM Thomas","year":"1998","journal-title":"Biochem J"},{"key":"pone.0319324.ref029","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.plantsci.2012.05.009","article-title":"Mesophyll diffusion conductance to CO2: an unappreciated central player in photosynthesis","author":"J Flexas","year":"2012","journal-title":"Plant Sci"},{"issue":"4","key":"pone.0319324.ref030","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1104\/pp.008250","article-title":"Temperature response of mesophyll conductance. Implications for the determination of Rubisco enzyme kinetics and for limitations to photosynthesis in vivo","volume":"130","author":"CJ Bernacchi","year":"2002","journal-title":"Plant Physiol"},{"issue":"4","key":"pone.0319324.ref031","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1111\/pce.12449","article-title":"Temperature responses of mesophyll conductance differ greatly between species","volume":"38","author":"S von Caemmerer","year":"2015","journal-title":"Plant Cell Environ"},{"key":"pone.0319324.ref032","doi-asserted-by":"crossref","first-page":"109153","DOI":"10.1016\/j.agrformet.2022.109153","article-title":"Quantitative expression of mesophyll conductance temperature response in the FvCB model and impacts on plant gas exchange estimations","volume":"325","author":"W Xue","year":"2022","journal-title":"Agric For Meteorol"},{"issue":"4","key":"pone.0319324.ref033","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1111\/tpj.14674","article-title":"Photorespiration in the context of Rubisco biochemistry, CO2 diffusion and metabolism","volume":"101","author":"FA Busch","year":"2020","journal-title":"Plant J"},{"issue":"4","key":"pone.0319324.ref034","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1104\/pp.69.4.921","article-title":"Temperature Dependence of Photosynthesis in Agropyron smithii Rydb.\u00a0: I. Factors affecting net CO2 uptake in intact leaves and contribution from ribulose-1,5-bisphosphate carboxylase measured in vivo and in vitro","volume":"69","author":"RK Monson","year":"1982","journal-title":"Plant Physiol"},{"issue":"4","key":"pone.0319324.ref035","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1104\/pp.59.4.587","article-title":"Rapid isolation of mesophyll cells from leaves of soybean for photosynthetic studies","volume":"59","author":"JC Servaites","year":"1977","journal-title":"Plant Physiol"},{"issue":"1","key":"pone.0319324.ref036","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1104\/pp.61.1.62","article-title":"Oxygen inhibition of photosynthesis and stimulation of photorespiration in soybean leaf cells","volume":"61","author":"JC Servaites","year":"1978","journal-title":"Plant Physiol"},{"issue":"2","key":"pone.0319324.ref037","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/gcb.16488","article-title":"Neglecting acclimation of photosynthesis under drought can cause significant errors in predicting leaf photosynthesis in wheat","volume":"29","author":"L Fang","year":"2023","journal-title":"Glob Chang Biol"},{"issue":"4","key":"pone.0319324.ref038","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1111\/gcb.15366","article-title":"Multi-hypothesis comparison of Farquhar and Collatz photosynthesis models reveals the unexpected influence of empirical assumptions at leaf and global scales","volume":"27","author":"AP Walker","year":"2021","journal-title":"Glob Chang Biol"},{"issue":"2\u20134","key":"pone.0319324.ref039","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/0168-1923(91)90002-8","article-title":"Physiological and environmental regulation of stomatal conductance, photosynthesis and transpiration: a model that includes a laminar boundary layer","volume":"54","author":"GJ Collatz","year":"1991","journal-title":"Agric For Meteorol"},{"issue":"8","key":"pone.0319324.ref040","doi-asserted-by":"crossref","first-page":"084009","DOI":"10.1088\/1748-9326\/ab79e5","article-title":"Inferring CO2 fertilization effect based on global monitoring land-atmosphere exchange with a theoretical model","volume":"15","author":"M Ueyama","year":"2020","journal-title":"Environ Res Lett"},{"key":"pone.0319324.ref041","first-page":"1535","article-title":"Climate change 2013: the physical science basis","volume-title":"Contribution of Working Group I to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change","author":"T Stocker","year":"2013"},{"issue":"4","key":"pone.0319324.ref042","first-page":"92","article-title":"Atmospheric CO\u2082 Concentration and other limiting factors in the growth of C\u2083 and C\u2084 plants","volume":"8","author":"A Boretti","year":"2019","journal-title":"Plants (Basel)"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0319324","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T17:31:27Z","timestamp":1744911087000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0319324"}},"subtitle":[],"editor":[{"given":"Susmita","family":"Lahiri (Ganguly),","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,4,17]]},"references-count":42,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,4,17]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0319324","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,17]]}}}