{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:53:27Z","timestamp":1792788807550,"version":"4.5.0"},"reference-count":110,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["Nos. 32060196, 32460211, 82360271 and 82201597"],"award-info":[{"award-number":["Nos. 32060196, 32460211, 82360271 and 82201597"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Yunnan Fundamental Research Projects","award":["202401AT070332"],"award-info":[{"award-number":["202401AT070332"]}]},{"name":"Joint Funds for Medical Specialization of KUST","award":["KUST-KH2023002Y"],"award-info":[{"award-number":["KUST-KH2023002Y"]}]},{"name":"Yunnan Ten Thousand Talents Plan Young and Elite Talents Project","award":["YNWR-QNBJ-2018-027, YNWR-QNBJ-2018-056"],"award-info":[{"award-number":["YNWR-QNBJ-2018-027, YNWR-QNBJ-2018-056"]}]},{"name":"The innovation team of stress and disorder in nervous system in Yunnan Province","award":["202305AS350011"],"award-info":[{"award-number":["202305AS350011"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Internet Gaming Disorder (IGD) is characterized by uncontrolled gaming behavior, leading to emotional distress, neglect of academic or life responsibilities, and damage to interpersonal relationships, all of which have serious negative impacts on individuals and society. IGD has been associated with neuropsychological impairments, especially executive function deficits, and emotional difficulties. Mindfulness interventions have been indicated to improve executive functions to varying degrees in individuals with IGD. The purpose of this study is to investigate whether the three subcomponents of executive function (i.e., inhibition, updating, and shifting) are impaired in individuals with internet gaming disorder, as well as to examine the effectiveness of a brief mindfulness intervention on executive function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 82 individuals diagnosed with IGD and 40 non-addicted gamers will be recruited for this study. These participants will be evenly divided into an intervention group and a control group at a ratio of 1:1. The intervention group will undergo a 7-day mindfulness training program focusing on breathing meditation, while the control group will receive progressive muscle relaxation training. Both groups\u2019 outcomes will be assessed at seven different time points. Primary outcome measures will include electroencephalography (EEG) data (band power, functional connectivity, source localization, and N2\/P3 amplitudes), behavioral metrics (response times and accuracy from psychological experimental paradigms), physiological indices (specifically heart rate variability), self-reported measures (game craving and mindfulness levels, executive function performance, and impulsivity emphasizing inhibitory control). Secondary outcome measures will encompass anxiety, stress, positive and negative affect, sleep quality, and other indicators such as demographic information, physical and mental health status, and the Big Five personality traits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This study aims to explore the efficacy of a brief mindfulness intervention on executive function impairments in IGD individuals and to elucidate its underlying neural mechanisms. It is anticipated that the findings will contribute to more targeted intervention strategies for executive function research, offering novel insights into the treatment of IGD and related cognitive dysfunctions. This study is expected to explore the effectiveness of brief mindfulness intervention on IGD and its underlying brain functional mechanisms, particularly providing more targeted intervention strategies for improving executive functions in this population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration<\/jats:title>\n                    <jats:p>Trial registration number: ChiCTR2400081509, registered on March 4th 2024. Protocol Version1.0.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0320305","type":"journal-article","created":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T17:58:21Z","timestamp":1743530301000},"page":"e0320305","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Protocol for a Randomized Controlled Trial to Enhance Executive Function via Brief Mindfulness Training in Individuals with Internet Gaming 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ed","year":"2013"},{"key":"pone.0320305.ref002","first-page":"104","article-title":"International Classification of Diseases - 11th revision: from design to implementation","volume":"54","author":"MSC Almeida","year":"2020","journal-title":"Rev Saude Publica"},{"key":"pone.0320305.ref003","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jpsychires.2022.06.049","article-title":"The prevalence and possible risk factors of internet gaming disorder among adolescents and young adults: Systematic reviews and meta-analyses","volume":"154","author":"Y-X Gao","year":"2022","journal-title":"J Psychiatr Res"},{"issue":"1","key":"pone.0320305.ref004","doi-asserted-by":"crossref","first-page":"e0191713","DOI":"10.1371\/journal.pone.0191713","article-title":"Lack of sleep is associated with internet use for leisure","volume":"13","author":"SY Kim","year":"2018","journal-title":"PLoS 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disorder","volume":"53","author":"M Wang","year":"2023","journal-title":"Psychol Med"},{"key":"pone.0320305.ref008","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1146\/annurev-psych-122414-033457","article-title":"Drug Addiction: Updating Actions to Habits to Compulsions Ten Years On","volume":"67","author":"BJ Everitt","year":"2016","journal-title":"Annu Rev Psychol"},{"issue":"11","key":"pone.0320305.ref009","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1038\/nn1584","article-title":"Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective","volume":"8","author":"A Bechara","year":"2005","journal-title":"Nat Neurosci"},{"key":"pone.0320305.ref010","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.jpsychires.2014.07.005","article-title":"A cognitive-behavioral model of Internet gaming disorder: theoretical underpinnings and clinical implications","volume":"58","author":"G Dong","year":"2014","journal-title":"J Psychiatr Res"},{"key":"pone.0320305.ref011","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neubiorev.2019.06.032","article-title":"The Interaction of Person-Affect-Cognition-Execution (I-PACE) model for addictive behaviors: Update, generalization to addictive behaviors beyond internet-use disorders, and specification of the process character of addictive behaviors","volume":"104","author":"M Brand","year":"2019","journal-title":"Neurosci Biobehav Rev"},{"key":"pone.0320305.ref012","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.neubiorev.2016.08.033","article-title":"Integrating psychological and neurobiological considerations regarding the development and maintenance of specific Internet-use disorders: An Interaction of Person-Affect-Cognition-Execution (I-PACE) model","volume":"71","author":"M Brand","year":"2016","journal-title":"Neurosci Biobehav 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Proposing Mechanisms of Action From a Conceptual and Neural Perspective","volume":"6","author":"BK H\u00f6lzel","year":"2011","journal-title":"Perspect Psychol Sci"},{"issue":"4","key":"pone.0320305.ref025","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.tics.2008.01.005","article-title":"Attention regulation and monitoring in meditation","volume":"12","author":"A Lutz","year":"2008","journal-title":"Trends Cogn Sci"},{"key":"pone.0320305.ref026","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.concog.2016.01.005","article-title":"Mindfulness meditation practice and executive functioning: Breaking down the benefit","volume":"40","author":"SN Gallant","year":"2016","journal-title":"Conscious Cogn"},{"key":"pone.0320305.ref027","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.copsyc.2019.02.012","article-title":"Does mindfulness training help working memory \u201cwork\u201d better?","volume":"28","author":"AP 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Kakko","year":"2019","journal-title":"Front Psychiatry"},{"issue":"50","key":"pone.0320305.ref037","doi-asserted-by":"crossref","first-page":"20254","DOI":"10.1073\/pnas.1112029108","article-title":"Meditation experience is associated with differences in default mode network activity and connectivity","volume":"108","author":"JA Brewer","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"5","key":"pone.0320305.ref038","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1001\/jamapsychiatry.2013.4546","article-title":"Relative efficacy of mindfulness-based relapse prevention, standard relapse prevention, and treatment as usual for substance use disorders: a randomized clinical trial","volume":"71","author":"S Bowen","year":"2014","journal-title":"JAMA Psychiatry"},{"issue":"4","key":"pone.0320305.ref039","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1037\/adb0000269","article-title":"Mindfulness-oriented recovery enhancement for internet gaming disorder 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Meditation Training Is Associated with Enhanced Subjective Attention and Stronger Posterior Cingulate-Rostrolateral Prefrontal Cortex Resting Connectivity","volume":"34","author":"TRA Kral","year":"2022","journal-title":"J Cogn Neurosci"},{"issue":"1","key":"pone.0320305.ref043","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1038\/s41386-021-01132-0","article-title":"The role of prefrontal cortex in cognitive control and executive function","volume":"47","author":"NP Friedman","year":"2022","journal-title":"Neuropsychopharmacology"},{"issue":"6","key":"pone.0320305.ref044","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.jphysparis.2013.05.001","article-title":"Prefrontal cortex and neural mechanisms of executive function","volume":"107","author":"S Funahashi","year":"2013","journal-title":"J Physiol Paris"},{"issue":"8","key":"pone.0320305.ref045","first-page":"827","article-title":"Mindfulness Meditation Training Reduces Gaming Cravings by Reshaping the Functional Connectivity Between the Default Mode Network and Executive Control-Related Brain Regions","volume":"9","author":"X Xu","year":"2024","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"key":"pone.0320305.ref046","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.chb.2013.11.004","article-title":"Family factors in Internet addiction among Chinese youth: A review of English- and Chinese-language studies","volume":"31","author":"W Li","year":"2014","journal-title":"Computers in Human Behavior"},{"issue":"1","key":"pone.0320305.ref047","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1556\/JBA.3.2014.004","article-title":"A preliminary investigation into the prevalence and prediction of problematic cell phone use","volume":"3","author":"P Smetaniuk","year":"2014","journal-title":"J Behav Addict"},{"issue":"1","key":"pone.0320305.ref048","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1186\/s12888-016-1083-3","article-title":"Prevalence and correlates of problematic smartphone use in a large random sample of Chinese undergraduates","volume":"16","author":"J Long","year":"2016","journal-title":"BMC Psychiatry"},{"issue":"2","key":"pone.0320305.ref049","doi-asserted-by":"crossref","first-page":"e1030","DOI":"10.1038\/tp.2017.1","article-title":"To use or not to use? Compulsive behavior and its role in smartphone addiction","volume":"7","author":"Y-H Lin","year":"2017","journal-title":"Transl Psychiatry"},{"issue":"7","key":"pone.0320305.ref050","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1037\/ccp0000324","article-title":"Brief mindfulness training for negative affectivity: A systematic review and meta-analysis","volume":"86","author":"MC Schumer","year":"2018","journal-title":"J Consult Clin Psychol"},{"issue":"12","key":"pone.0320305.ref051","doi-asserted-by":"crossref","first-page":"e0279621","DOI":"10.1371\/journal.pone.0279621","article-title":"Effectiveness of brief mindfulness intervention for college students\u2019 problematic smartphone use: The mediating role of self-control","volume":"17","author":"F Liu","year":"2022","journal-title":"PLoS One"},{"issue":"5","key":"pone.0320305.ref052","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1002\/cpp.2453","article-title":"Effects of short-term mindfulness-based training on executive function: Divergent but promising","volume":"27","author":"H Zhou","year":"2020","journal-title":"Clin Psychol Psychother"},{"issue":"10","key":"pone.0320305.ref053","first-page":"1188","article-title":"A proposed criterion for clinical diagnosis of internet addiction","volume":"33","author":"R Tao","year":"2008","journal-title":"Medical Journal of Chinese People\u2019s Liberation Army"},{"issue":"1","key":"pone.0320305.ref054","first-page":"3","article-title":"Internet gaming disorder in adolescents: Review and prospect","volume":"28","author":"W Xi","year":"2022","journal-title":"Chinese Journal of Applied Psychology"},{"key":"pone.0320305.ref055","doi-asserted-by":"crossref","first-page":"152319","DOI":"10.1016\/j.comppsych.2022.152319","article-title":"Exploring Internet gaming disorder: an updated perspective of empirical evidence (from 2016 to 2021)","volume":"116","author":"G Mestre-Bach","year":"2022","journal-title":"Compr Psychiatry"},{"issue":"10","key":"pone.0320305.ref056","first-page":"CD011723","article-title":"Mindfulness-based interventions for substance use disorders","volume":"10","author":"SB Goldberg","year":"2021","journal-title":"Cochrane Database Syst Rev"},{"key":"pone.0320305.ref057","unstructured":"Wang M. Sex differences in internet gaming disorder in neural responses to gaming cues [Master\u2019s Dissertation]: Zhejiang Normal University; 2019."},{"issue":"3","key":"pone.0320305.ref058","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1089\/cpb.1998.1.237","article-title":"Internet Addiction: The Emergence of a New Clinical Disorder","volume":"1","author":"KS Young","year":"1998","journal-title":"CyberPsychology & Behavior"},{"issue":"9","key":"pone.0320305.ref059","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1111\/add.12457","article-title":"An international consensus for assessing internet gaming disorder using the new DSM-5 approach","volume":"109","author":"NM Petry","year":"2014","journal-title":"Addiction"},{"issue":"5","key":"pone.0320305.ref060","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/S0924-9338(97)83296-8","article-title":"The Mini International Neuropsychiatric Interview (MINI). A short diagnostic structured interview: reliability and validity according to the CIDI","volume":"12","author":"Y Lecrubier","year":"1997","journal-title":"Eur psychiatr"},{"issue":"7","key":"pone.0320305.ref061","first-page":"493","article-title":"Evaluation of the reliability and validity of Chinese version of the Mini International Neuropsychiatric Interview in patients with mental disorders","volume":"23","author":"T Si","year":"2009","journal-title":"Chinese Mental Health Journal"},{"key":"pone.0320305.ref062","unstructured":"Zhang Y. Study on the differences of executive function of college students in different levels of electronic games and Internet Game Addicts-Taking \u201cLeague of Legends\u201d game as an example [Master\u2019s Dissertation]: Wuhan Sports University; 2019."},{"key":"pone.0320305.ref063","unstructured":"Liu B. A Study on the Attention Bias towards Game-Related Information in Adolescents with Internet Gaming Disorder [Master\u2019s Dissertation]: Tianjin Normal University; 2020."},{"key":"pone.0320305.ref064","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.jpsychires.2021.01.032","article-title":"Mindfulness intervention for mild cognitive impairment led to attention-related improvements and neuroplastic changes: Results from a 9-month randomized control trial","volume":"135","author":"J Yu","year":"2021","journal-title":"J Psychiatr Res"},{"issue":"6","key":"pone.0320305.ref065","doi-asserted-by":"crossref","first-page":"e782","DOI":"10.1093\/geront\/gnz022","article-title":"Effects of Meditation and Mind-Body Exercises on Older Adults\u2019 Cognitive Performance: A Meta-analysis","volume":"59","author":"JSY Chan","year":"2019","journal-title":"Gerontologist"},{"issue":"6","key":"pone.0320305.ref066","doi-asserted-by":"crossref","first-page":"e2416684","DOI":"10.1001\/jamanetworkopen.2024.16684","article-title":"Efficacy and Neural Mechanisms of Mindfulness Meditation Among Adults With Internet Gaming Disorder: A Randomized Clinical Trial","volume":"7","author":"H Ni","year":"2024","journal-title":"JAMA Netw Open"},{"key":"pone.0320305.ref067","doi-asserted-by":"crossref","first-page":"714","DOI":"10.3389\/fpsyg.2016.00714","article-title":"Brain Activity toward Gaming-Related Cues in Internet Gaming Disorder during an Addiction Stroop Task","volume":"7","author":"Y Zhang","year":"2016","journal-title":"Front Psychol"},{"issue":"2","key":"pone.0320305.ref068","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1556\/2006.2020.00020","article-title":"Altered brain network topology related to working memory in internet addiction","volume":"9","author":"H Wang","year":"2020","journal-title":"J Behav Addict"},{"issue":"8","key":"pone.0320305.ref069","doi-asserted-by":"crossref","first-page":"e0290171","DOI":"10.1371\/journal.pone.0290171","article-title":"Immediate and short-term effects of single-task and motor-cognitive dual-task on executive function","volume":"18","author":"W Zhang","year":"2023","journal-title":"PLoS One"},{"issue":"2","key":"pone.0320305.ref070","doi-asserted-by":"crossref","first-page":"e13469","DOI":"10.1111\/psyp.13469","article-title":"Dysfunctional cognitive control and reward processing in adolescents with Internet gaming disorder","volume":"57","author":"Q Li","year":"2020","journal-title":"Psychophysiology"},{"issue":"4","key":"pone.0320305.ref071","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1089\/cyber.2017.0486","article-title":"Altered Heart Rate Variability During Gaming in Internet Gaming Disorder","volume":"21","author":"D Lee","year":"2018","journal-title":"Cyberpsychol Behav Soc Netw"},{"issue":"2","key":"pone.0320305.ref072","first-page":"144","article-title":"Mindfulness-based interventions in context: Past, present, and future.","volume":"10","author":"J Kabat-Zinn","year":"2003","journal-title":"Clinical Psychology: Science and Practice"},{"issue":"3","key":"pone.0320305.ref073","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1300\/J137v13n03_04","article-title":"Progressive Muscle Relaxation","volume":"13","author":"MS McCallie","year":"2006","journal-title":"Journal of Human Behavior in the Social Environment"},{"issue":"1","key":"pone.0320305.ref074","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1177\/1073191105283504","article-title":"Using self-report assessment methods to explore facets of mindfulness","volume":"13","author":"RA Baer","year":"2006","journal-title":"Assessment"},{"issue":"1","key":"pone.0320305.ref075","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s12955-021-01692-1","article-title":"Psychometric properties of the Chinese version of Five Facet Mindfulness Questionnaire-short form in cancer patients: a Bayesian structural equation modeling approach","volume":"19","author":"TCT Fong","year":"2021","journal-title":"Health Qual Life Outcomes"},{"issue":"8","key":"pone.0320305.ref076","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1007\/s12671-021-01655-z","article-title":"The Toronto Mindfulness Scale: Psychometric Properties of the Chinese Version","volume":"12","author":"S Yu","year":"2021","journal-title":"Mindfulness"},{"issue":"3","key":"pone.0320305.ref077","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1111\/j.1369-1600.2011.00405.x","article-title":"Brain correlates of craving for online gaming under cue exposure in subjects with Internet gaming addiction and in remitted subjects","volume":"18","author":"C-H Ko","year":"2013","journal-title":"Addict Biol"},{"issue":"1","key":"pone.0320305.ref078","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1080\/14622200020032051","article-title":"Evaluation of the brief questionnaire of smoking urges (QSU-brief) in laboratory and clinical settings","volume":"3","author":"LS Cox","year":"2001","journal-title":"Nicotine Tob Res"},{"issue":"6","key":"pone.0320305.ref079","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1093\/ntr\/ntq063","article-title":"Evaluation of the Chinese versions of the Minnesota nicotine withdrawal scale and the questionnaire on smoking urges-brief","volume":"12","author":"X Yu","year":"2010","journal-title":"Nicotine Tob Res"},{"issue":"6","key":"pone.0320305.ref080","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1002\/1097-4679(199511)51:6<768::AID-JCLP2270510607>3.0.CO;2-1","article-title":"Factor structure of the Barratt impulsiveness scale","volume":"51","author":"JH Patton","year":"1995","journal-title":"J Clin Psychol"},{"issue":"6","key":"pone.0320305.ref081","first-page":"1199","article-title":"Reliability and validity of Chinese version of Brief Barratt Impulsiveness Scale","volume":"28","author":"MC LUO","year":"2020","journal-title":"Chinese Journal of Clinical Psychology"},{"issue":"5","key":"pone.0320305.ref082","first-page":"463","article-title":"Development of adolescent executive function scale","volume":"23","author":"C Huang","year":"2014","journal-title":"Chinese Journal of Behavioral Medicine and Brain Science"},{"issue":"12","key":"pone.0320305.ref083","first-page":"1851","article-title":"Self-Rating Scale of Sleep (SRSS)","volume":"20","author":"J Li","year":"2012","journal-title":"China Journal of Health Psychology"},{"issue":"4","key":"pone.0320305.ref084","first-page":"443","article-title":"Psychometric properties of the Chinese versions of DASS-21 in Chinese college students","volume":"18","author":"X Gong","year":"2010","journal-title":"Chinese Journal of Clinical Psychology"},{"issue":"6","key":"pone.0320305.ref085","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1037\/0022-3514.54.6.1063","article-title":"Development and validation of brief measures of positive and negative affect: the PANAS scales","volume":"54","author":"D Watson","year":"1988","journal-title":"J Pers Soc Psychol"},{"issue":"1","key":"pone.0320305.ref086","first-page":"54","article-title":"Applicability of the Positive and Negative Affect Scale in Chinese","volume":"17","author":"L Huang","year":"2003","journal-title":"Chinese Mental Health Journal"},{"key":"pone.0320305.ref087","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.bandc.2015.01.003","article-title":"On the use (and misuse?) of the Edinburgh Handedness Inventory","volume":"94","author":"JM Edlin","year":"2015","journal-title":"Brain Cogn"},{"key":"pone.0320305.ref088","doi-asserted-by":"crossref","DOI":"10.1037\/t68472-000","article-title":"Edinburgh Handedness Inventory--Chinese Version","author":"N Yang","year":"2018","journal-title":"PsycTESTS Dataset"},{"issue":"9","key":"pone.0320305.ref089","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1046\/j.1525-1497.2001.016009606.x","article-title":"The PHQ-9: validity of a brief depression severity measure","volume":"16","author":"K Kroenke","year":"2001","journal-title":"J Gen Intern Med"},{"issue":"4","key":"pone.0320305.ref090","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/appy.12103","article-title":"Validity and reliability of Patient Health Questionnaire-9 and Patient Health Questionnaire-2 to screen for depression among college students in China","volume":"5","author":"Y-L Zhang","year":"2013","journal-title":"Asia Pac Psychiatry"},{"issue":"10","key":"pone.0320305.ref091","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","article-title":"A brief measure for assessing generalized anxiety disorder: the GAD-7","volume":"166","author":"RL Spitzer","year":"2006","journal-title":"Arch Intern Med"},{"issue":"12","key":"pone.0320305.ref092","first-page":"939","article-title":"Diagnostic test of screening generalized anxiety disorders in general hospital psychological department with GAD-7","volume":"29","author":"Q Shan","year":"2015","journal-title":"Chinese Mental Health Journal"},{"issue":"4","key":"pone.0320305.ref093","first-page":"454","article-title":"Development of the Chinese Big Five Personality Inventory (CBF-PI) III: Psychometric properties of CBF-PI brief version","volume":"19","author":"M Wang","year":"2011","journal-title":"Chinese Journal of Clinical Psychology"},{"issue":"03","key":"pone.0320305.ref094","first-page":"399","article-title":"Measuring adult attachment: Chinese adaptation of the ECR scale","volume":"38","author":"K-K Li-Tonggui","year":"2006","journal-title":"Acta Psychologica Sinica"},{"issue":"5","key":"pone.0320305.ref095","first-page":"1115","article-title":"The influence of adult attachment style on attitude toward professional psychological seeking help: The mediating effect of the expected results of self disclosure","volume":"29","author":"X Kong","year":"2021","journal-title":"Chinese Journal of Clinical Psychology"},{"key":"pone.0320305.ref096","doi-asserted-by":"crossref","first-page":"103888","DOI":"10.1016\/j.actpsy.2023.103888","article-title":"The effect of mindfulness training on executive function in youth with depression","volume":"235","author":"M Dong","year":"2023","journal-title":"Acta Psychol (Amst)"},{"key":"pone.0320305.ref097","unstructured":"Yao Y. Effect of Negative Emotion on Executive Women Function Physiological Cycle and Mindfulness Intervention [Master\u2019s Dissertation]: Yunnan Normal University; 2023."},{"issue":"5","key":"pone.0320305.ref098","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1111\/acps.13225","article-title":"Adverse events in meditation practices and meditation-based therapies: a systematic review","volume":"142","author":"M Farias","year":"2020","journal-title":"Acta Psychiatr Scand"},{"issue":"3","key":"pone.0320305.ref099","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1016\/j.ijcard.2013.06.086","article-title":"Meditation: should a cardiologist care?","volume":"168","author":"S Olex","year":"2013","journal-title":"Int J Cardiol"},{"issue":"3","key":"pone.0320305.ref100","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1007\/s12671-019-01296-3","article-title":"The Utility of Heart Rate Variability in Mindfulness Research","volume":"11","author":"G Christodoulou","year":"2020","journal-title":"Mindfulness"},{"issue":"2","key":"pone.0320305.ref101","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.ijpsycho.2013.07.006","article-title":"Mindfulness (Vipassana) meditation: effects on P3b event-related potential and heart rate variability","volume":"90","author":"LC Delgado-Pastor","year":"2013","journal-title":"Int J Psychophysiol"},{"issue":"3","key":"pone.0320305.ref102","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.ijpsycho.2013.06.017","article-title":"Mindfulness meditation, well-being, and heart rate variability: a preliminary investigation into the impact of intensive Vipassana meditation","volume":"89","author":"JR Krygier","year":"2013","journal-title":"Int J Psychophysiol"},{"issue":"9","key":"pone.0320305.ref103","doi-asserted-by":"crossref","first-page":"e36662","DOI":"10.2196\/36662","article-title":"Content and Effectiveness of Web-Based Treatments for Online Behavioral Addictions: Systematic Review","volume":"9","author":"JJ Park","year":"2022","journal-title":"JMIR Ment Health"},{"key":"pone.0320305.ref104","doi-asserted-by":"crossref","first-page":"100027","DOI":"10.1016\/j.chbr.2020.100027","article-title":"A brief internet-delivered intervention for the reduction of gaming-related harm: A feasibility study","volume":"2","author":"JJ Park","year":"2020","journal-title":"Computers in Human Behavior Reports"},{"key":"pone.0320305.ref105","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.ypmed.2016.07.014","article-title":"Intervention to reduce recreational screen-time in adolescents: Outcomes and mediators from the \u201cSwitch-Off 4 Healthy Minds\u201d (S4HM) cluster randomized controlled trial","volume":"91","author":"MJ Babic","year":"2016","journal-title":"Prev Med"},{"issue":"10","key":"pone.0320305.ref106","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1089\/cyber.2018.0070","article-title":"A Week Without Using Social Media: Results from an Ecological Momentary Intervention Study Using Smartphones","volume":"21","author":"S Stieger","year":"2018","journal-title":"Cyberpsychol Behav Soc Netw"},{"key":"pone.0320305.ref107","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/0-387-27652-1_4","article-title":"Design and evaluation of consumer health information web sites.","volume-title":"Consumer Health Informatics: Informing Consumers and Improving Health Care","author":"G. Eysenbach","year":"2005"},{"issue":"1","key":"pone.0320305.ref108","doi-asserted-by":"crossref","first-page":"e30","DOI":"10.2196\/jmir.1602","article-title":"Supportive accountability: a model for providing human support to enhance adherence to eHealth interventions","volume":"13","author":"DC Mohr","year":"2011","journal-title":"J Med Internet Res"},{"issue":"1","key":"pone.0320305.ref109","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1186\/s12889-021-10749-1","article-title":"Person-centred interventions for problem gaming: a stepped care approach","volume":"21","author":"JJ Park","year":"2021","journal-title":"BMC Public Health"},{"issue":"3","key":"pone.0320305.ref110","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1556\/2006.4.2015.026","article-title":"Commentary on: Are we overpathologizing everyday life? A tenable blueprint for behavioral addiction research. The diagnostic pitfalls of surveys: If you score positive on a test of addiction, you still have a good chance not to be addicted","volume":"4","author":"A Maraz","year":"2015","journal-title":"J Behav Addict"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0320305","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T18:02:57Z","timestamp":1743530577000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0320305"}},"subtitle":[],"editor":[{"given":"Metin","family":"\u00c7\u0131naro\u011flu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,4,1]]},"references-count":110,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,4,1]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0320305","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,1]]}}}