{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T22:50:53Z","timestamp":1788648653291,"version":"build-2803163510"},"reference-count":21,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Guangzhou Health Science and Technology Project","award":["20241A011025"],"award-info":[{"award-number":["20241A011025"]}]},{"name":"Guangdong Medical Science and Technology Research Foundation","award":["A2023164"],"award-info":[{"award-number":["A2023164"]}]},{"name":"Liuzhou Science and Technology Planning Project","award":["2024SB0104A002"],"award-info":[{"award-number":["2024SB0104A002"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>\nObjective\n<\/jats:title>\n<jats:p>Hyperbilirubinemia is a common cause of hospital readmission among neonates, but the factors contributing to post-discharge readmission remain unclear. Our study aimed to identify predictive factors associated with readmission for neonatal hyperbilirubinemia.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>\nMethods\n<\/jats:title>\n<jats:p>This retrospective case-control study included 421 neonates born at \u2265\u200935 weeks of gestation with hyperbilirubinemia between January and December 2021. The neonates were divided into a readmission group and a control group, and logistic regression was used to identify predictive factors associated with readmission.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>\nResults\n<\/jats:title>\n<jats:p>Among the 421 neonates studied, 32 (7.6%) were readmitted. Logistic regression analysis identified preterm birth (&lt;37 weeks), ABO hemolysis, Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency, and Total Serum Bilirubin (TSB) level at discharge as significant predictive factors for readmission due to hyperbilirubinemia in newborns. Additionally, a decrease in birth weight was significantly linked to an increased risk of readmission (OR\u2009=\u20090.998, P\u2009=\u20090.013), although the effect size was relatively small.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>\nConclusions\n<\/jats:title>\n<jats:p>Prolonging hospitalization and implementing robust post-discharge monitoring may be essential for neonates with prematurity, ABO hemolysis, G6PD deficiency, or elevated TSB levels at discharge.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0320767","type":"journal-article","created":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T20:45:50Z","timestamp":1743540350000},"page":"e0320767","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Predictive factors for readmission due to neonatal hyperbilirubinemia: A retrospective case-control 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