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The methodology encompasses six key steps: collecting raw data from Electronic Medical Records (EMRs), revising feature attributes with expert input, data preprocessing, model adaptation, training machine learning models (CART, Random Forest, and XGBOOST), and evaluating the results. Furthermore, based on analysis of experimental measurement parameter values, 21 feature attributes which relate to support early diagnose the Colorectal cancer disease are extracted. Among different models implemented in our case, XGBOOST is the most suitable model to solve this problem. The system assists clinicians to select clinical tests and medical procedures for a colorectal cancer patient. Therefore, patients can save the waiting time and medical examination costs. 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