{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T02:41:56Z","timestamp":1778294516523,"version":"3.51.4"},"reference-count":34,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009243","name":"Direction G\u00e9n\u00e9rale de l\u2019offre de Soins","doi-asserted-by":"publisher","award":["PHRC-2016"],"award-info":[{"award-number":["PHRC-2016"]}],"id":[{"id":"10.13039\/501100009243","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec024\">\n<jats:title>Background<\/jats:title>\n<jats:p>Short versions of health-related quality of life measures are essential for the development of preference-based measures used to obtain the quality-adjustment weights needed to calculate quality-adjusted life years (QALYs) in health economic evaluations. Using data from the randomized TRAIN study, which compared the efficacy of two cognitive training programs in patients with alcohol use disorder (AUD) recently detoxified at five centers in France from 2019 to 2023 (n=227), we report the development and psychometrics of the AQoLS-Brief, a short version of the initial 34-item Alcohol Quality of Life Scale (AQoLS).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec025\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Baseline data on, age, sex, AUD severity, drinking characteristics and consequences of alcohol including the AQoLS were collected. One item per dimension of the AQoLS was chosen following predefined rules. Construct validity of the AQoLS-brief was documented: internal consistency was assessed using Cronbach\u2019s alpha and external validity was assessed with external drinking and non-drinking variables via univariate analyses, a confirmatory factorial analysis (CFA) and a multivariate linear regression.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec026\">\n<jats:title>Results:<\/jats:title>\n<jats:p>The 7-item AQoLS-Brief demonstrated good internal consistency (Cronbach alpha= 0.80) and very high correlation with the long version AQoLS (rho=0.95). The CFA confirmed the unidimensionality of the AQoLS-Brief. Severity of AUD, as measured by the number of DSM-5 alcohol criteria and the number of heavy drinking days, and the dimension Sadness of the Affective Neuroscience Personality Scales were the heaviest contributors to the AQoLS-Brief score.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec027\">\n<jats:title>Conclusions:<\/jats:title>\n<jats:p>The AQoLS-Brief is a short version of the AQoLS with good psychometrics, enhancing its use in clinical practice and research, and representing a significant step toward establishing a relevant and specific preference-based measures for calculating QALYs in AUD populations.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0321365","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T17:25:49Z","timestamp":1745947549000},"page":"e0321365","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["AQoLS-Brief: Development and psychometric 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Conceptual framework and item selection","volume":"30","author":"Jr Ware JE","year":"1992","journal-title":"Med Care"},{"issue":"1","key":"pone.0321365.ref017","doi-asserted-by":"crossref","first-page":"e018996","DOI":"10.1136\/bmjopen-2017-018996","article-title":"Developing a dementia-specific preference--based quality of life measure (AD-5D) in Australia: a valuation study protocol","volume":"8","author":"TA Comans","year":"2018","journal-title":"BMJ Open"},{"issue":"7","key":"pone.0321365.ref018","doi-asserted-by":"crossref","first-page":"e0219905","DOI":"10.1371\/journal.pone.0219905","article-title":"What attributes should be included in a discrete choice experiment related to health technologies? 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Substance related and addictive disorders fact sheet. 2013."},{"issue":"7","key":"pone.0321365.ref021","first-page":"28","article-title":"The clinical global impressions scale: applying a research tool in clinical practice","volume":"4","author":"J Busner","year":"2007","journal-title":"Psychiatry (Edgmont)"},{"issue":"1","key":"pone.0321365.ref022","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0376-8716(96)01263-X","article-title":"The reliability of the Alcohol Timeline Followback when administered by telephone and by computer","volume":"42","author":"LC Sobell","year":"1996","journal-title":"Drug Alcohol Depend"},{"issue":"1","key":"pone.0321365.ref023","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1080\/15294145.2003.10773410","article-title":"The Affective Neuroscience Personality Scales: Normative Data and Implications","volume":"5","author":"KL Davis","year":"2003","journal-title":"Neuropsychoanalysis"},{"issue":"12","key":"pone.0321365.ref024","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/j.addbeh.2009.07.001","article-title":"The Substance Use Risk Profile Scale: a scale measuring traits linked to reinforcement-specific substance use profiles","volume":"34","author":"PA Woicik","year":"2009","journal-title":"Addict Behav"},{"key":"pone.0321365.ref025","doi-asserted-by":"crossref","first-page":"149","DOI":"10.3389\/fpubh.2018.00149","article-title":"Best Practices for Developing and Validating Scales for Health, Social, and Behavioral Research: A Primer","volume":"6","author":"GO Boateng","year":"2018","journal-title":"Front Public Health"},{"key":"pone.0321365.ref026","doi-asserted-by":"crossref","DOI":"10.1201\/9781003054313","article-title":"Computational aspects of psychometric methods: With R","author":"P Martinkov\u00e1","year":"2023"},{"issue":"2","key":"pone.0321365.ref027","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1177\/001316445401400215","article-title":"Procedures for the Analysis of Classroom Tests","volume":"14","author":"RL Ebel","year":"1954","journal-title":"Educ Psychol Measur"},{"issue":"2","key":"pone.0321365.ref028","doi-asserted-by":"crossref","DOI":"10.18637\/jss.v048.i02","article-title":"lavaan: AnRPackage for Structural Equation Modeling","volume":"48","author":"Y Rosseel","year":"2012","journal-title":"J Stat Soft"},{"key":"pone.0321365.ref029","doi-asserted-by":"crossref","DOI":"10.1002\/9781119579038","volume-title":"Structural Equation Modeling with lavaan","author":"K Gana","year":"2018"},{"key":"pone.0321365.ref030","volume-title":"LISREL 7: A Guide to the Program and Applications","author":"KG J\u00f6reskog","year":"1989"},{"key":"pone.0321365.ref031","first-page":"621","volume-title":"Construct validity","author":"K Grimm","year":"2012"},{"key":"pone.0321365.ref032","volume-title":"psych: Procedures for Psychological, Psychometric, and Personality Research","year":"2024"},{"issue":"2","key":"pone.0321365.ref033","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1093\/alcalc\/agy089","article-title":"Systematic Reviews of Mindfulness and Acceptance and Commitment Therapy for Alcohol Use Disorder: Should we be using Third Wave Therapies?","volume":"54","author":"SP Byrne","year":"2019","journal-title":"Alcohol Alcohol"},{"issue":"6","key":"pone.0321365.ref034","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1111\/acer.12734","article-title":"MoCA as a Screening Tool of Neuropsychological Deficits in Alcohol-Dependent Patients","volume":"39","author":"R Alarcon","year":"2015","journal-title":"Alcohol Clin Exp Res"}],"container-title":["PLOS One"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0321365","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T17:26:21Z","timestamp":1745947581000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0321365"}},"subtitle":[],"editor":[{"given":"Shivanand","family":"Kattimani","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,4,29]]},"references-count":34,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,4,29]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0321365","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,29]]}}}