{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:24:06Z","timestamp":1788481446916,"version":"build-2803163510"},"reference-count":15,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T00:00:00Z","timestamp":1753747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"cureblindness.org"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Purpose<\/jats:title>\n<jats:p>To evaluate the average motility of the implant and custom-made prosthesis (CMP) in various gazes following Myoconjunctival enucleation, the surgical duration, and the complications encountered at a tertiary eye hospital.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>This was a prospective, non-randomized interventional study. Recti muscles were sutured to the fornices before enucleation of the eyeball to minimize surgical time and the need for additional sutures. Thirty-five consecutive patients meeting the inclusion criteria were enrolled. Data on surgery time, complications, and implant\/prosthesis motility were recorded and analyzed.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>The mean surgical duration was 39.43\u2009\u00b1\u20094.97 minutes. Mean PMMA implant movement was 2.34 mm in elevation, 2.26 mm in depression, 2.74 mm in abduction, and 2.71 mm in adduction. Custom-made prosthesis (CMP) movement was 2.40 mm in elevation, 2.51 mm in depression, 2.74 mm in abduction, and 2.66 mm in adduction. Complications were minimal: one intraoperative superior rectus slippage, a few cases with early postoperative nausea, vomiting, and headache, all resolved within a week. At six weeks, one suture granuloma and one shallow inferior fornix were noted and managed. Patient satisfaction was high (88.57%), with a mean Likert score of 4.25\u2009\u00b1\u20090.65 (1\u2009=\u2009Very unsatisfied to 5\u2009=\u2009Very satisfied). No patient reported dissatisfaction.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Myoconjunctival enucleation offers favorable implant and prosthesis motility, a relatively short surgical duration, and minimal complications. High patient satisfaction supports the myoconjunctival enucleation technique as a reliable and well-tolerated surgical option.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0321703","type":"journal-article","created":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T17:26:01Z","timestamp":1753809961000},"page":"e0321703","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Myoconjunctival Enucleation Study (MES): Outcome of Myoconjunctival Enucleation Technique with Polymethyl Methacrylate (PMMA) implant and Custom-made prosthesis (CMP) in a tertiary eye care center in Nepal"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5948-5266","authenticated-orcid":true,"given":"Hom Bahadur","family":"Gurung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Purnima 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Nunery","year":"1983","journal-title":"Ophthalmology"},{"key":"pone.0321703.ref005","author":"K Koushan","year":"2021"},{"issue":"3","key":"pone.0321703.ref006","article-title":"Myoconjunctival enucleation for enhanced implant motility: Results of a randomised prospective study","volume":"52","author":"U Yadava","year":"2004","journal-title":"Indian J Ophthalmol"},{"key":"pone.0321703.ref007","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1159\/000531871","article-title":"Orbital Complications and Cost Analysis of Enucleation by Myoconjunctival versus Conventional Techniques for Retinoblastoma","volume":"9","author":"L Lando","year":"2023","journal-title":"Ocul Oncol Pathol"},{"issue":"5","key":"pone.0321703.ref008","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1097\/00002341-200209000-00004","article-title":"A simple algorithm for selection of implant size for enucleation and evisceration: a prospective study","volume":"18","author":"SA 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