{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T02:46:00Z","timestamp":1785465960122,"version":"3.56.0"},"reference-count":56,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T00:00:00Z","timestamp":1746144000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec>\n<jats:title>Background<\/jats:title>\n<jats:p>Identifying underlying subgroups might be a way to examine the development of co-occurrent substance use and delinquency. The aim of this study was to identify latent classes of substance misuse and delinquency in adolescence and which general risk factors are associated with these classes.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>Data of two waves from a national representative Swedish birth cohort was used that consisted of 4,013 randomly selected adolescents (Male\u2009=\u20091,798, Female\u2009=\u20092,201, Missing\u2009=\u200914) Latent class analysis was used to identify classes of substance misuse and delinquency at age 17\/18 and. logistic regression analysis was used to assess risk factors at age 15\/16.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>Identified classes were: \u201cLow\/abstainers\u201d (74.80%, n\u2009=\u20092858, Male\u2009=\u20091191 Female\u2009=\u20091656, Missing\u2009=\u200911) which acted as reference, \u201cAlcohol only\u201d (22.21%, n\u2009=\u2009849, Male\u2009=\u2009420, Female\u2009=\u2009426, Missing\u2009=\u20093), \u201cPolydrug use and crime\u201d (2.15%, n\u2009=\u200982, Male\u2009=\u200952, Female\u2009=\u200930) and \u201cHigh crime\u201d (0.84%, n\u2009=\u200932, Male\u2009=\u200930, Females\u2009=\u20092). Factors associated with belonging to any classes engaging in substance use and delinquency were lower parental support, supervision, peer problems, and higher conduct problems, sensation-seeking behavior, distrust in society, and truancy.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Most people did not engage in substance use or delinquency. When accounting for less frequent behaviors such as normative adolescent drinking and one-time events of crime and drug use, about 3% of the population engaged in co-occurring substance use and delinquency. Several different factors from several domains where related to belonging to a class that used substances and\/or engaged in delinquency. There were indications that the most extensive users and offender displayed a wide variety of severe level risk factors, which could have implications for targeted interventions. Though, statistical power was a problem and future research should use larger samples or alternative methods.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0322515","type":"journal-article","created":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T17:25:26Z","timestamp":1746206726000},"page":"e0322515","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Latent classes of substance use and delinquency in a Swedish national sample of adolescents and associated risk 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global burden of disease attributable to alcohol and drug use in 195 countries and territories: A systematic analysis for the Global Burden of Disease 2016","volume":"5","author":"GBD 2016 Alcohol and Drug Use Collaborators","year":"2018","journal-title":"Lancet Psychiatry"},{"key":"pone.0322515.ref002","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.eclinm.2019.09.014","article-title":"Mental health outcomes associated with the use of amphetamines: A systematic review and meta-analysis","volume":"16","author":"R McKetin","year":"2019","journal-title":"EClinicalMedicine"},{"issue":"9","key":"pone.0322515.ref003","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1016\/j.socscimed.2009.12.015","article-title":"Violence victimization among Finnish university studies: Prevalence, symptoms and healthcare usage","volume":"70","author":"K Bj\u00f6rklund","year":"2010","journal-title":"Soc Sci 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Collaborators","year":"2020","journal-title":"Lancet"},{"key":"pone.0322515.ref007","volume-title":"Brottsf\u00f6rebyggande r\u00e5det: Nationella trygghetsunders\u00f6kningen: Om utsatthet, trygghet och f\u00f6rtroende","year":"2024"},{"issue":"10","key":"pone.0322515.ref008","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1111\/add.13877","article-title":"Substance use disorders in prisoners: an updated systematic review and meta-regression analysis in recently incarcerated men and women","volume":"112","author":"S Fazel","year":"2017","journal-title":"Addiction"},{"key":"pone.0322515.ref009","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.drugalcdep.2016.08.003","article-title":"Trends and correlates of substance use disorders among probationers and parolees in the United States 2002\u20132014","volume":"167","author":"NE Fearn","year":"2016","journal-title":"Drug Alcohol 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Examining the relationship between drug onset and duration with criminal outcomes in an African American cohort","volume":"110","author":"KM Green","year":"2020","journal-title":"Addict Behav"},{"issue":"3","key":"pone.0322515.ref014","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1037\/0033-2909.107.3.341","article-title":"Effects of alcohol on human aggression: an integrative research review","volume":"107","author":"BJ Bushman","year":"1990","journal-title":"Psychol Bull"},{"issue":"4","key":"pone.0322515.ref015","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1177\/002204268501500406","article-title":"The drugs\/violence nexus: A tripartite conceptual framework","volume":"15","author":"PJ Goldstein","year":"1985","journal-title":"J Drug Issues"},{"key":"pone.0322515.ref016","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.drugpo.2019.02.006","article-title":"Prevalence and correlates of selling illicit cannabis among people who use drugs in Vancouver. 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States","volume":"45","author":"M DeLisi","year":"2015","journal-title":"J Drug Issues"},{"issue":"10","key":"pone.0322515.ref036","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1017\/S0033291713000081","article-title":"A latent class analysis of drug abuse in a national Swedish sample","volume":"43","author":"KS Kendler","year":"2013","journal-title":"Psychol Med"},{"issue":"1","key":"pone.0322515.ref037","doi-asserted-by":"crossref","first-page":"114","DOI":"10.3109\/10826084.2014.961611","article-title":"Patterns of substance use, delinquency, and risk factors among adolescent inhalant users","volume":"50","author":"B Nakawaki","year":"2015","journal-title":"Subst Use Misuse"},{"issue":"1","key":"pone.0322515.ref038","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/ab.20365","article-title":"The three latent classes of adolescent delinquency and the risk factors for membership in each class","volume":"37","author":"PA Hasking","year":"2011","journal-title":"Aggress Behav"},{"issue":"2","key":"pone.0322515.ref039","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1093\/eurpub\/ckad022","article-title":"Children with problem-drinking parents in a Swedish national sample: is the risk of harm related to the severity of parental drinking?","volume":"33","author":"M Ramstedt","year":"2023","journal-title":"Eur J Public Health"},{"key":"pone.0322515.ref040","volume-title":"The Swedish Act concerning the ethical review of research involving humans (SFS 2003:460)"},{"key":"pone.0322515.ref041","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1016\/j.jadohealth.2024.02.014","article-title":"Early drinking onset and subsequent alcohol use in late adolescence: A longitudinal study of drinking patterns","volume":"74","author":"L Sj\u00f6din","year":"2024","journal-title":"J Adolesc 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(BIS-Brief)","volume":"25","author":"L Steinberg","year":"2013","journal-title":"Psychol Assess"},{"key":"pone.0322515.ref046","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0191-8869(01)00032-0","article-title":"Reliability and validity of a brief measure of sensation seeking","volume":"32","author":"RH Hoyle","year":"2002","journal-title":"Pers Individ Differ"},{"issue":"3","key":"pone.0322515.ref047","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.ijlp.2008.04.002","article-title":"Assessing callous-unemotional traits in adolescent offenders: validation of the Inventory of Callous-Unemotional Traits","volume":"31","author":"ER Kimonis","year":"2008","journal-title":"Int J Law Psychiatry"},{"issue":"3","key":"pone.0322515.ref048","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1037\/1040-3590.7.3.309","article-title":"Constructing validity: Basic issues in objective scale development","volume":"7","author":"LA Clark","year":"1995","journal-title":"Psychol Assess"},{"key":"pone.0322515.ref049","volume-title":"Stata Statistical Software","author":"StataCorp","year":"2023"},{"issue":"1","key":"pone.0322515.ref050","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1097\/CCM.0000000000004710","article-title":"Practitioner\u2019s guide to latent class analysis: Methodological considerations and common pitfalls","volume":"49","author":"P Sinha","year":"2021","journal-title":"Crit Care Med"},{"key":"pone.0322515.ref051","volume-title":"IBM SPSS Statistics for Windows","author":"IBM Corp","year":"2023"},{"issue":"11","key":"pone.0322515.ref052","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.addbeh.2011.05.006","article-title":"Alcohol, violence, and the Alcohol Myopia Model: preliminary findings and implications for prevention","volume":"36","author":"PR Giancola","year":"2011","journal-title":"Addict 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