{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:37:39Z","timestamp":1792802259198,"version":"4.5.0"},"reference-count":36,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T00:00:00Z","timestamp":1746662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"New Faculty Research Grant of Yeungnam University","award":["224A580066"],"award-info":[{"award-number":["224A580066"]}],"id":[{"id":"https:\/\/ror.org\/05yc6p159","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec013\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Obstructive sleep apnea (OSA) increases the risk of all-cause and cardiovascular mortality. This study aimed to investigate the association between OSA and atherogenic risk in the Koreans.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec014\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from 8,158 participants (mean age, 57.9\u2009\u00b1\u200911.7; male\/female, 1:1.4) obtained from the Korea National Health and Nutrition Examination Survey between 2019 and 2021. OSA risk was screened using the STOP-BANG score, and atherogenic risk was measured using the atherogenic index of plasma (AIP). Logistic regression was used to evaluate the association between the STOP-BANG scores and high AIP and subgroups according to the presence of diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec015\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The proportions of individuals with atherogenic risk (AIP\u2009&gt;\u20090.24) were 13.7%, 27.6%, and 34.7% in the low-, intermediate-, and high-OSA risk groups (p\u2009&lt;\u20090.001). After adjustment, individuals with intermediate and high OSA risk had 1.35 (95% confidence interval [CI], 1.16\u20131.58; p\u2009&lt;\u20090.001) and 1.32 (95% CI, 1.08\u20131.61; p\u2009=\u20090.006) times higher odds of having atherogenic risk than those with low OSA risk. Among patients without diabetes, high OSA risk was not an independent factor affecting atherogenic risk (hazard ratio [HR], 1.17; 95% CI, 0.93\u20131.47). However, among patients with diabetes, compared with those with low OSA risk, those with intermediate (HR, 1.51; 95% CI, 1.05\u20132.19) and high OSA risk (HR, 1.58; 95% CI, 1.02\u20132.46) had significantly increased atherogenic risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec016\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>OSA is linked to increased atherogenic risk in the Koreans, especially in individuals with diabetes, thus highlighting the importance of routine OSA screening to manage and reduce cardiovascular risks.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0322897","type":"journal-article","created":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T16:07:38Z","timestamp":1746720458000},"page":"e0322897","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Association between obstructive sleep apnea risk and atherosclerosis: A nationwide cross-sectional study in the Korean population"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4436-0158","authenticated-orcid":true,"given":"Il Rae","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Geun","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3336-7557","authenticated-orcid":true,"given":"Seung Min","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Sung","family":"Moon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Sung","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5945-3395","authenticated-orcid":true,"given":"Kyu Chang","family":"Won","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,5,8]]},"reference":[{"issue":"8","key":"pone.0322897.ref001","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S2213-2600(19)30198-5","article-title":"Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis","volume":"7","author":"AV Benjafield","year":"2019","journal-title":"Lancet Respir Med"},{"issue":"4","key":"pone.0322897.ref002","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1002\/oby.20288","article-title":"Consequences of obstructive sleep apnea on metabolic profile: a Population-Based Survey","volume":"21","author":"SM 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