{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T23:41:28Z","timestamp":1768347688526,"version":"3.49.0"},"reference-count":24,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T00:00:00Z","timestamp":1746748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>Research has focused on pain perception of individuals with Borderline Personality Disorder, but there is a lack of research regarding pain perception for other types of Personality Disorders. The present study explored associations between the perception of experimentally-induced acute pain of individuals without acute or chronic pain with Borderline, as well as Histrionic, and Schizotypal, Personality Disorders traits. The primary question of interest was whether any personality disorders were associated with altered pain perception. Fifty-two participants had pain induced by a cold-pressor task, and were evaluated for personality disorder traits. Psychophysiological perception of pain was measured using pain threshold and tolerance tests, subjective reports of pain were taken using the McGill Pain Questionnaire, and physiological aspects were measured using Galvanic Skin Response as an index of physiological arousal. The results showed significant associations between Histrionic Personality Disorder and subjective reports of the sensory aspects, and intensity, of pain, but not with psychophysiological or physiological responses (although caution is needed in interpreting the results of multiple tests). There were no significant associations regarding pain perception and Borderline, or Schizotypal, Personality Disorders. These results are preliminary, but provide novel suggestions regarding the impact of Personality Disorder on pain perception and guidance for future research has been provided.<\/jats:p>","DOI":"10.1371\/journal.pone.0323004","type":"journal-article","created":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T17:28:30Z","timestamp":1746811710000},"page":"e0323004","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pain perception in personality disorders"],"prefix":"10.1371","volume":"20","author":[{"given":"Spyridoula","family":"Bourtzoni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8157-0747","authenticated-orcid":true,"given":"Phil","family":"Reed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2025,5,9]]},"reference":[{"key":"pone.0323004.ref001","doi-asserted-by":"crossref","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"2013"},{"key":"pone.0323004.ref002","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1192\/bjp.188.5.423","article-title":"Prevalence and correlates of personality disorder in Great Britain","volume":"188","author":"J Coid","year":"2006","journal-title":"Br J Psychiatry"},{"issue":"6","key":"pone.0323004.ref003","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.biopsych.2006.09.019","article-title":"DSM-IV personality disorders in the National Comorbidity Survey Replication","volume":"62","author":"MF Lenzenweger","year":"2007","journal-title":"Biol Psychiatry"},{"key":"pone.0323004.ref004","first-page":"274","article-title":"Histrionic personality disorder and pain\u2013 a psychological case for the surgeon?","volume":"55","author":"M Brinkers","year":"2017","journal-title":"Manuelle Medizin"},{"issue":"5","key":"pone.0323004.ref005","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.genhosppsych.2015.05.004","article-title":"Associations of borderline personality with pain, problems with medications and suicidality in a community sample of chronic non-cancer pain patients prescribed opioids for pain","volume":"37","author":"G Campbell","year":"2015","journal-title":"Gen Hosp Psychiatry"},{"issue":"3","key":"pone.0323004.ref006","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1177\/17423953221110150","article-title":"Personality disorders and outcome after multidisciplinary pain therapy","volume":"19","author":"J Heyn","year":"2023","journal-title":"Chronic Illn"},{"issue":"7","key":"pone.0323004.ref007","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1046\/j.1526-4610.2002.02156.x","article-title":"Borderline personality disorder and the chronic headache patient: review and management recommendations","volume":"42","author":"JR Saper","year":"2002","journal-title":"Headache"},{"issue":"8","key":"pone.0323004.ref008","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1007\/s11916-013-0350-y","article-title":"Borderline personality disorder and chronic pain: a practical approach to evaluation and treatment","volume":"17","author":"V Kalira","year":"2013","journal-title":"Curr Pain Headache Rep"},{"key":"pone.0323004.ref009","first-page":"40","article-title":"Borerline personality and the pain paradox","volume":"4","author":"RA Sansone","year":"2007","journal-title":"Psychiatry"},{"key":"pone.0323004.ref010","author":"Office for National Statistics (2017).","year":"2016"},{"key":"pone.0323004.ref011","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.psychres.2010.07.050","article-title":"Exploring the affective component of pain perception during aversive stimulation in borderline personality disorder","volume":"186","author":"L C\u00e1rdenas-Morales","year":"2011","journal-title":"Psychiatry Res"},{"issue":"4","key":"pone.0323004.ref012","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1521\/pedi_2013_27_094","article-title":"Borderline personality disorder features and risk for prescription opioid use disorders","volume":"27","author":"SL Tragesser","year":"2013","journal-title":"J Pers Disord"},{"issue":"10","key":"pone.0323004.ref013","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1097\/j.pain.0000000000000275","article-title":"Deficits in pain perception in borderline personality disorder: results from the thermal grill illusion","volume":"156","author":"R Bekrater-Bodmann","year":"2015","journal-title":"Pain"},{"issue":"3","key":"pone.0323004.ref014","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1097\/AJP.0b013e318192be97","article-title":"Are patients with schizophrenia insensitive to pain? 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