{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T23:46:44Z","timestamp":1782517604385,"version":"3.54.5"},"reference-count":29,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:00:00Z","timestamp":1751414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>This work aims to promote early and accurate diagnosis of Temporal Lobe Epilepsy (TLE) by developing state-of-the-art deep learning techniques, with the goal of minimizing the consequences of epilepsy on individuals and society. Current approaches for TLE detection have drawbacks, including applicability to particular MRI sequences, moderate ability to determine the side of the onset zones, and weak cross-validation with different patient groups, which hampers their practical use. To overcome these difficulties, a new Hybrid Attention-Enhanced Transformer Network (HAETN) is introduced for early TLE diagnosis. This approach uses newly developed Fuzzy-AAL Segmentation Framework (FASF) which is a combination of Fuzzy Possibilistic C-Means (FPCM) algorithm for segmentation of tissue and AAL labelling for labelling of tissues. Furthermore, an effective feature selection method is proposed using the Dipper- grey wolf optimization (DGWO) algorithm to improve the performance of the proposed model. The performance of the proposed method is thoroughly assessed by accuracy, sensitivity, and F1-score. The performance of the suggested approach is evaluated on the Temporal Lobe Epilepsy-UNAM MRI Dataset, where it attains an accuracy of 98.61%, a sensitivity of 99.83%, and F1-score of 99.82%, indicating its efficiency and applicability in clinical practice.<\/jats:p>","DOI":"10.1371\/journal.pone.0325126","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T17:37:26Z","timestamp":1751477846000},"page":"e0325126","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":4,"title":["MRI based early Temporal Lobe Epilepsy detection using DGWO based optimized HAETN and Fuzzy-AAL Segmentation Framework (FASF)"],"prefix":"10.1371","volume":"20","author":[{"given":"Hasim","family":"Khan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed 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