{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T20:51:48Z","timestamp":1790023908782,"version":"4.0.1"},"reference-count":65,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T00:00:00Z","timestamp":1754524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004318","name":"Microsoft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004318","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000121","name":"Division of Mathematical Sciences","doi-asserted-by":"publisher","award":["1815764"],"award-info":[{"award-number":["1815764"]}],"id":[{"id":"10.13039\/100000121","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004883","name":"Illinois Department of Agriculture","doi-asserted-by":"publisher","award":["SC-20-10"],"award-info":[{"award-number":["SC-20-10"]}],"id":[{"id":"10.13039\/100004883","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013078","name":"St. Olaf College","doi-asserted-by":"publisher","award":["CURI"],"award-info":[{"award-number":["CURI"]}],"id":[{"id":"10.13039\/100013078","id-type":"DOI","asserted-by":"publisher"}]},{"name":"c3.ai"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>\n                    Honey bees contribute substantially to the world economy through pollination services and honey production. In the U.S. alone, honey bee pollination is estimated to contribute at least $11 billion annually, primarily through the pollination of specialty crops. However, beekeepers lose about half of their hives every season due to disease, insecticides, and other environmental factors. Here, we explore and validate a spatiotemporal statistical model of\n                    <jats:italic>Varroa destructor<\/jats:italic>\n                    mite burden (in mites\/300 bees) in managed honey bee colonies, exploring the impact of both environmental factors and beekeeper behaviors. We examine risk factors for\n                    <jats:italic>Varroa<\/jats:italic>\n                    infestation using apiary inspection data collected across the state of Illinois over 2018\u20132019, and we test the models using inspection data from 2020\u20132021. After accounting for spatial and temporal trends, we find that most environmental factors (e.g., floral quality, insecticide load) are not predictive of\n                    <jats:italic>Varroa<\/jats:italic>\n                    intensity, while lower numbers of nearby apiaries and several beekeeper behaviors (e.g., supplemental feeding and mite monitoring\/treatment) are protective against\n                    <jats:italic>Varroa<\/jats:italic>\n                    . Interestingly, while monitoring\n                    <jats:italic>and<\/jats:italic>\n                    treating for\n                    <jats:italic>Varroa<\/jats:italic>\n                    is protective, treating\n                    <jats:italic>without<\/jats:italic>\n                    monitoring is no more effective than not treating at all. This is an important result supporting Integrated Pest Management (IPM) approaches.\n                  <\/jats:p>","DOI":"10.1371\/journal.pone.0325801","type":"journal-article","created":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T17:43:18Z","timestamp":1754588598000},"page":"e0325801","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Spatiotemporal, environmental, and behavioral predictors of Varroa mite intensity in managed honey bee apiaries"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2687-3817","authenticated-orcid":true,"given":"Laura","family":"Boehm Vock","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren M.","family":"Mossman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoi","family":"Rapti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6164-1344","authenticated-orcid":true,"given":"Adam G.","family":"Dolezal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara M.","family":"Clifton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,8,7]]},"reference":[{"key":"pone.0325801.ref001","unstructured":"Spivak M, Browning Z, Goblirsch M, Lee K, Otto C, Smart M. Why does bee health matter? The science surrounding honey bee health concerns and what we can do about it. 2017."},{"issue":"6229","key":"pone.0325801.ref002","doi-asserted-by":"crossref","DOI":"10.1126\/science.1255957","article-title":"Bee declines driven by combined stress from parasites, pesticides, and lack of flowers","volume":"347","author":"D Goulson","year":"2015","journal-title":"Science."},{"issue":"5","key":"pone.0325801.ref003","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1890\/120126","article-title":"Threats to an ecosystem service: pressures on pollinators","volume":"11","author":"AJ Vanbergen","year":"2013","journal-title":"Front Ecol Environ."},{"issue":"4","key":"pone.0325801.ref004","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0153531","article-title":"Intensively cultivated landscape and varroa mite infestation are associated with reduced honey bee nutritional state","volume":"11","author":"AG Dolezal","year":"2016","journal-title":"PLoS One."},{"issue":"3","key":"pone.0325801.ref005","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1600-0706.2010.18644.x","article-title":"How many flowering plants are pollinated by animals?","volume":"120","author":"J Ollerton","year":"2011","journal-title":"Oikos."},{"issue":"7632","key":"pone.0325801.ref006","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1038\/nature20588","article-title":"Safeguarding pollinators and their values to human well-being","volume":"540","author":"SG Potts","year":"2016","journal-title":"Nature."},{"issue":"3","key":"pone.0325801.ref007","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.ecolecon.2008.06.014","article-title":"Economic valuation of the vulnerability of world agriculture confronted with pollinator decline","volume":"68","author":"N Gallai","year":"2009","journal-title":"Ecol Econ."},{"issue":"5","key":"pone.0325801.ref008","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0037235","article-title":"Insect pollinated crops, insect pollinators and US agriculture: trend analysis of aggregate data for the period 1992 -2009","volume":"7","author":"NW Calderone","year":"2012","journal-title":"PLoS One."},{"issue":"11","key":"pone.0325801.ref009","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.cub.2009.03.071","article-title":"The global stock of domesticated honey bees is growing slower than agricultural demand for pollination","volume":"19","author":"MA Aizen","year":"2009","journal-title":"Curr Biol."},{"key":"pone.0325801.ref010","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.mbs.2016.02.012","article-title":"Disease dynamics of honeybees with Varroa destructor as parasite and virus vector","volume":"275","author":"Y Kang","year":"2016","journal-title":"Math Biosci."},{"issue":"88","key":"pone.0325801.ref011","doi-asserted-by":"crossref","first-page":"20130650","DOI":"10.1098\/rsif.2013.0650","article-title":"Modelling the spread of American foulbrood in honeybees","volume":"10","author":"S Datta","year":"2013","journal-title":"J R Soc Interface."},{"key":"pone.0325801.ref012","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.1365-2656.2004.00776.x","article-title":"The dynamics of virus epidemics in Varroa-infested honey bee colonies","volume":"73","author":"DJT Sumpter","year":"2004","journal-title":"J Animal Ecol."},{"issue":"12","key":"pone.0325801.ref013","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1111\/ele.12188","article-title":"Chronic sublethal stress causes bee colony failure","volume":"16","author":"J Bryden","year":"2013","journal-title":"Ecol Lett."},{"key":"pone.0325801.ref014","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.ecolmodel.2013.06.005","article-title":"Dynamic modelling of honey bee (Apis mellifera) colony growth and failure","volume":"265","author":"S Russell","year":"2013","journal-title":"Ecol Model."},{"issue":"4","key":"pone.0325801.ref015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0018491","article-title":"A quantitative model of honey bee colony population dynamics","volume":"6","author":"DS Khoury","year":"2011","journal-title":"PLoS One."},{"issue":"5","key":"pone.0325801.ref016","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0059084","article-title":"Modelling food and population dynamics in honey bee colonies","volume":"8","author":"DS Khoury","year":"2013","journal-title":"PLoS One."},{"issue":"11","key":"pone.0325801.ref017","doi-asserted-by":"crossref","first-page":"160444","DOI":"10.1098\/rsos.160444","article-title":"Age structure is critical to the population dynamics and survival of honeybee colonies","volume":"3","author":"MI Betti","year":"2016","journal-title":"R Soc Open Sci."},{"issue":"10","key":"pone.0325801.ref018","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0110237","article-title":"Effects of infection on honey bee population dynamics: a model","volume":"9","author":"MI Betti","year":"2014","journal-title":"PLoS One."},{"issue":"6","key":"pone.0325801.ref019","doi-asserted-by":"crossref","first-page":"9606","DOI":"10.3934\/mbe.2021471","article-title":"Review on mathematical modeling of honeybee population dynamics","volume":"18","author":"J Chen","year":"2021","journal-title":"Math Biosci Eng."},{"issue":"4","key":"pone.0325801.ref020","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1080\/00218839.2017.1344496","article-title":"A national survey of managed honey bee 2015 \u20132016 annual colony losses in the USA","volume":"56","author":"K Kulhanek","year":"2017","journal-title":"J Apicult Res."},{"issue":"4","key":"pone.0325801.ref021","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1080\/00218839.2016.1153294","article-title":"A national survey of managed honey bee 2014 \u20132015 annual colony losses in the USA","volume":"54","author":"N Seitz","year":"2022","journal-title":"J Apicult Res."},{"key":"pone.0325801.ref022","doi-asserted-by":"crossref","unstructured":"Muhammad N, Eberl HJ. A simple model of between-hive transmission of nosemosis. In: International Conference on Applied Mathematics, Modeling and Computational Science. 2017. p. 385\u201395.","DOI":"10.1007\/978-3-319-99719-3_35"},{"issue":"9","key":"pone.0325801.ref023","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1111\/1365-2664.13461","article-title":"Industrial bees: the impact of apicultural intensification on local disease prevalence","volume":"56","author":"LJ Bartlett","year":"2019","journal-title":"J Appl Ecol."},{"key":"pone.0325801.ref024","doi-asserted-by":"crossref","first-page":"1102457","DOI":"10.3389\/fevo.2023.1102457","article-title":"Seasonal differences in Varroa destructor population growth in western honey bee (Apis mellifera) colonies","volume":"11","author":"CJ Jack","year":"2023","journal-title":"Front Ecol Evol."},{"key":"pone.0325801.ref025","unstructured":"Dolezal A. Illinois apiary inspection dataset. 2025. https:\/\/doi.org\/10.7910\/DVN\/LSK1N5"},{"key":"pone.0325801.ref026","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.3389\/fmicb.2019.01331","article-title":"High load of deformed wing virus and Varroa destructor infestation are related to weakness of honey bee colonies in southern Spain","volume":"10","author":"S Barroso-Ar\u00e9valo","year":"2019","journal-title":"Front Microbiol."},{"issue":"1","key":"pone.0325801.ref027","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1186\/s12915-022-01463-4","article-title":"Vector-virus interaction affects viral loads and co-occurrence","volume":"20","author":"N Eliash","year":"2022","journal-title":"BMC Biol."},{"issue":"3","key":"pone.0325801.ref028","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0057540","article-title":"Varroa-virus interaction in collapsing honey bee colonies","volume":"8","author":"RM Francis","year":"2013","journal-title":"PLoS One."},{"key":"pone.0325801.ref029","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1099\/vir.0.005579-0","article-title":"Deformed wing virus: replication and viral load in mites (Varroa destructor)","volume":"90","author":"S Gisder","year":"2009","journal-title":"J Gen Virol."},{"issue":"4","key":"pone.0325801.ref030","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1603\/EC10037","article-title":"Practical sampling plans for Varroa destructor (Acari: Varroidae) in Apis mellifera (Hymenoptera: Apidae) colonies and apiaries","volume":"103","author":"KV Lee","year":"2010","journal-title":"J Econ Entomol."},{"key":"pone.0325801.ref031","unstructured":"Beescape Development Team. https:\/\/beescape.psu.edu\/."},{"key":"pone.0325801.ref032","doi-asserted-by":"crossref","first-page":"101366","DOI":"10.1016\/j.ecoinf.2021.101366","article-title":"Beescape: characterizing user needs for environmental decision support in beekeeping","author":"AC Robinson","year":"2021","journal-title":"Ecol Inform."},{"issue":"5","key":"pone.0325801.ref033","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1111\/ele.12082","article-title":"A global quantitative synthesis of local and landscape effects on wild bee pollinators in agroecosystems","volume":"16","author":"CM Kennedy","year":"2013","journal-title":"Ecol Lett."},{"issue":"1","key":"pone.0325801.ref034","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1073\/pnas.1517685113","article-title":"Modeling the status, trends, and impacts of wild bee abundance in the United States","volume":"113","author":"I Koh","year":"2016","journal-title":"Proc Natl Acad Sci U S A."},{"key":"pone.0325801.ref035","doi-asserted-by":"crossref","unstructured":"Cressie N. Statistics for spatial data. Wiley; 1993.","DOI":"10.1002\/9781119115151"},{"key":"pone.0325801.ref036","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.prevetmed.2016.07.013","article-title":"Key management practices to prevent high infestation levels of Varroa destructor in honey bee colonies at the beginning of the honey yield season","volume":"131","author":"A Giacobino","year":"2016","journal-title":"Prev Vet Med."},{"issue":"8","key":"pone.0325801.ref037","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0182814","article-title":"Honey bee (Apis mellifera) colony health and pathogen composition in migratory beekeeping operations involved in California almond pollination","volume":"12","author":"W Glenny","year":"2017","journal-title":"PLoS One."},{"issue":"1","key":"pone.0325801.ref038","doi-asserted-by":"crossref","first-page":"42","DOI":"10.13102\/sociobiology.v64i1.1183","article-title":"Honey bee (Apis mellifera) health in stationary and migratory apiaries","volume":"64","author":"LG Cestaro","year":"2017","journal-title":"Sociobiology."},{"issue":"1","key":"pone.0325801.ref039","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.sste.2010.10.001","article-title":"Spatio-temporal epidemiology: principles and opportunities","volume":"2","author":"JR Meliker","year":"2011","journal-title":"Spat Spatiotemporal Epidemiol."},{"key":"pone.0325801.ref040","unstructured":"Wood SN. Generalized additive models: an introduction with R. Boca Raton, FL: Chapman and Hall\/CRC; 2006."},{"key":"pone.0325801.ref041","doi-asserted-by":"crossref","unstructured":"Agresti A. Categorical data analysis (2nd Edn). Hoboken, New Jersey: Wiley; 2002.","DOI":"10.1002\/0471249688"},{"issue":"1","key":"pone.0325801.ref042","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/1467-9868.00374","article-title":"Thin-plate regression splines","volume":"65","author":"SN Wood","year":"2003","journal-title":"J Roy Statist Soc B."},{"issue":"467","key":"pone.0325801.ref043","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1198\/016214504000000980","article-title":"Stable and efficient multiple smoothing parameter estimation for generalized additive models","volume":"99","author":"SN Wood","year":"2004","journal-title":"J Am Statist Assoc."},{"key":"pone.0325801.ref044","unstructured":"Wood SN. Mixed GAM computation vehicle with GCV\/AIC\/REML smoothness estimation. 2015."},{"issue":"6","key":"pone.0325801.ref045","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1109\/TAC.1974.1100705","article-title":"A new look at the statistical model identification","volume":"19","author":"H Akaike","year":"1974","journal-title":"IEEE Trans Automat Contr."},{"key":"pone.0325801.ref046","unstructured":"Standifer LN, Moeller FE, Kauffeld NM, Herbert EW, Shimanuki H. Supplemental feeding of honey bee colonies. Department of Agriculture, Science and Education Administration; 1978."},{"key":"pone.0325801.ref047","unstructured":"Standifer L. Honey bee nutrition and supplemental feeding. Beekeeping in the United States. 1980;(335):39."},{"issue":"2","key":"pone.0325801.ref048","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1080\/0005772X.1997.11099335","article-title":"Feeding sugar syrup to honey bee colonies to improve pollination: a review","volume":"78","author":"RM Goodwin","year":"1997","journal-title":"Bee World."},{"key":"pone.0325801.ref049","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1007\/s13593-015-0327-9","article-title":"Eight principles of integrated pest management","volume":"35","author":"M Barzman","year":"2015","journal-title":"Agronom Sustain Develop."},{"key":"pone.0325801.ref050","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.cois.2018.02.006","article-title":"Feedbacks between nutrition and disease in honey bee health","volume":"26","author":"AG Dolezal","year":"2018","journal-title":"Curr Opin Insect Sci."},{"issue":"1","key":"pone.0325801.ref051","doi-asserted-by":"crossref","first-page":"10156","DOI":"10.1038\/s41598-019-46453-9","article-title":"Impact of nutritional stress on the honeybee colony health","volume":"9","author":"B Branchiccela","year":"2019","journal-title":"Sci Rep."},{"issue":"4","key":"pone.0325801.ref052","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1051\/apido:2003032","article-title":"Swarming in honey bees (Apis mellifera) and Varroa destructor population development in Sweden","volume":"34","author":"I Fries","year":"2003","journal-title":"Apidologie."},{"issue":"4","key":"pone.0325801.ref053","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1111\/1365-2664.12836","article-title":"The carry-over effects of pollen shortage decrease the survival of honeybee colonies in farmlands","volume":"54","author":"F Requier","year":"2017","journal-title":"J Appl Ecol."},{"issue":"3","key":"pone.0325801.ref054","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1093\/jisesa\/ieae056","article-title":"Neonicotinoid exposure increases Varroa destructor (Mesostigmata: Varroidae) mite parasitism severity in honey bee colonies and is not mitigated by increased colony genetic diversity","volume":"24","author":"LJ Bartlett","year":"2024","journal-title":"J Insect Sci."},{"key":"pone.0325801.ref055","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.cois.2021.02.005","article-title":"Honey robbing: could human changes to the environment transform a rare foraging tactic into a maladaptive behavior?","volume":"45","author":"CC Rittschof","year":"2021","journal-title":"Curr Opin Insect Sci."},{"issue":"6","key":"pone.0325801.ref056","article-title":"Mite bombs or robber lures? The roles of drifting and robbing in Varroa destructor transmission from collapsing honey bee colonies to their neighbors","volume":"14","author":"DT Peck","year":"2019","journal-title":"PLoS One."},{"issue":"5","key":"pone.0325801.ref057","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1051\/apido:2008032","article-title":"Horizontal transmission of Paenibacillus larvae spores between honey bee (Apis mellifera) colonies through robbing","volume":"39","author":"A Lindstr\u00f6m","year":"2008","journal-title":"Apidologie."},{"key":"pone.0325801.ref058","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1007\/s13592-014-0267-4","article-title":"Risky robbing is a job for short-lived and infected worker honeybees","volume":"45","author":"K Kuszewska","year":"2014","journal-title":"Apidologie."},{"issue":"4","key":"pone.0325801.ref059","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/s10493-020-00562-7","article-title":"Can supplementary pollen feeding reduce Varroa mite and virus levels and improve honey bee colony survival?","volume":"82","author":"G DeGrandi-Hoffman","year":"2020","journal-title":"Exp Appl Acarol."},{"issue":"1","key":"pone.0325801.ref060","doi-asserted-by":"crossref","first-page":"7092","DOI":"10.1038\/s41598-021-86558-8","article-title":"Accelerated Varroa destructor population growth in honey bee (Apis mellifera) colonies is associated with visitation from non-natal bees","volume":"11","author":"K Kulhanek","year":"2021","journal-title":"Sci Rep."},{"key":"pone.0325801.ref061","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.prevetmed.2014.04.002","article-title":"Risk factors associated with the presence of Varroa destructor in honey bee colonies from east-central Argentina","volume":"115","author":"A Giacobino","year":"2014","journal-title":"Prev Vet Med."},{"key":"pone.0325801.ref062","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.ijppaw.2022.05.004","article-title":"Migratory beekeeping and its influence on the prevalence and dispersal of pathogens to managed and wild bees","volume":"18","author":"V Mart\u00ednez-L\u00f3pez","year":"2022","journal-title":"Int J Parasitol Parasites Wildl."},{"key":"pone.0325801.ref063","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.prevetmed.2012.08.004","article-title":"Idiopathic brood disease syndrome and queen events as precursors of colony mortality in migratory beekeeping operations in the eastern United States","volume":"108","author":"DR Tarpy","year":"2013","journal-title":"Prev Vet Med."},{"issue":"1","key":"pone.0325801.ref064","doi-asserted-by":"crossref","first-page":"22","DOI":"10.3390\/microorganisms9010022","article-title":"The effect of migratory beekeeping on the infestation rate of parasites in honey bee (Apis mellifera) colonies and on their genetic variability","volume":"9","author":"L Jara","year":"2020","journal-title":"Microorganisms."},{"key":"pone.0325801.ref065","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.5812","article-title":"Home sick: impacts of migratory beekeeping on honey bee (Apis mellifera) pests, pathogens, and colony size","volume":"6","author":"SA Alger","year":"2018","journal-title":"PeerJ."}],"container-title":["PLOS One"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0325801","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T17:43:28Z","timestamp":1754588608000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0325801"}},"subtitle":[],"editor":[{"given":"Olav","family":"Rueppell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,8,7]]},"references-count":65,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2025,8,7]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0325801","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,7]]}}}