{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T16:49:38Z","timestamp":1774889378852,"version":"3.50.1"},"reference-count":58,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T00:00:00Z","timestamp":1749686400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>The relationship between postoperative physical changes and the development of homolateral neuropathic pain (HLNP) following mastectomy and lymph node resection remains poorly understood. In this study, we aimed to investigate whether early postoperative physical and symptom-based assessments could predict HLNP occurrence at 4 months post-surgery. Fifty-seven breast cancer survivors were included, with HLNP defined as a painDETECT Questionnaire score\u2009\u2265\u200913 at 4 months. Independent variables included patient demographics, physical function metrics including pectoralis minor length index (PMI), and questionnaire-based evaluations at 1 month postoperatively. Multivariate logistic regression identified systemic therapy side effects (ST) (odds ratio [OR]: 1.056; 95% confidence interval [CI]: 1.015\u20131.098) and PMI (OR: 0.204; 95% CI: 0.043\u20130.977) as significant predictors of HLNP. Receiver operating characteristic curve analysis identified cutoff values of 23.81 for ST and 9.82 for PMI. Reconstruction type and adjuvant therapy influenced the correlation between PMI and the number of resected lymph nodes, unlike external rotation metrics. Early assessment of ST and PMI facilitates HLNP risk prediction following breast cancer surgery. Multimodal interventions, including targeted physical therapy, may mitigate HLNP risk, highlighting the importance of early postoperative care.<\/jats:p>","DOI":"10.1371\/journal.pone.0326119","type":"journal-article","created":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T17:40:53Z","timestamp":1749750053000},"page":"e0326119","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pectoralis minor length index at 1 month postoperative can predict homolateral neuropathic pain 4 months after mastectomy with lymph node resection"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1160-8252","authenticated-orcid":true,"given":"Asall","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2554-8083","authenticated-orcid":true,"given":"Chunghwi","family":"Yi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myungki","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2050-5503","authenticated-orcid":true,"given":"Ui-Jae","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae-Young","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujin","family":"Myung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun Joo","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hee-Chul","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7984-9661","authenticated-orcid":true,"given":"Jaewon","family":"Beom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2025,6,12]]},"reference":[{"issue":"3","key":"pone.0326119.ref001","doi-asserted-by":"crossref","first-page":"207","DOI":"10.4048\/jbc.2023.26.e27","article-title":"Breast cancer statistics in Korea, 2019","volume":"26","author":"JE Choi","year":"2023","journal-title":"J Breast Cancer"},{"issue":"10125","key":"pone.0326119.ref002","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S0140-6736(17)33326-3","article-title":"Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37\u2008513\u2008025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries","volume":"391","author":"C Allemani","year":"2018","journal-title":"Lancet"},{"issue":"4","key":"pone.0326119.ref003","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1007\/s00520-020-05668-7","article-title":"Factors associated with upper limb dysfunction in breast cancer survivors","volume":"29","author":"TC Siqueira","year":"2021","journal-title":"Support Care Cancer"},{"key":"pone.0326119.ref004","first-page":"217","article-title":"Pain terms: a current list with definitions and notes on usage","volume":"3","author":"H Merskey","year":"1986","journal-title":"Pain"},{"key":"pone.0326119.ref005","doi-asserted-by":"crossref","first-page":"17002","DOI":"10.1038\/nrdp.2017.2","article-title":"Neuropathic pain","volume":"3","author":"L Colloca","year":"2017","journal-title":"Nat Rev Dis Primers"},{"issue":"11","key":"pone.0326119.ref006","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1097\/j.pain.0000000000001004","article-title":"The prevalence of neuropathic pain is high after treatment for breast cancer: a systematic review","volume":"158","author":"E Ilhan","year":"2017","journal-title":"Pain"},{"issue":"8","key":"pone.0326119.ref007","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/j.jclinepi.2015.03.010","article-title":"Neuropathic pain screening questionnaires have limited measurement properties. 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