{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T04:42:15Z","timestamp":1777178535841,"version":"3.51.4"},"reference-count":35,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T00:00:00Z","timestamp":1750032000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Public Welfare Applied Research Project of Huzhou Science and Technology Bureau","award":["2022GYB58"],"award-info":[{"award-number":["2022GYB58"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>Sodium pentachlorophenate (PCP-Na) is a toxic preservative used in wood products, posing potential health risks through food contact materials. A rapid analytical method combining ultrasonic-assisted liquid-liquid extraction with ultra-performance liquid chromatography-high resolution mass spectrometry (UA-LLE-UPLC-HRMS) was developed for the determination of PCP-Na residues in bamboo and wooden cutting boards. Sample pretreatment involved ultrasonic extraction using methanol\/water (50:50 v\/v, 2.0% ammonia), followed by liquid-liquid purification with n-hexane\/ethyl acetate (60:40 v\/v). After solvent evaporation under nitrogen, the residue was reconstituted in the initial mobile phase. Chromatographic separation was achieved on an Acquity UPLC BEH C18 column (2.1 mm\u2009\u00d7\u2009100\u2009mm, 1.7 \u00b5m) using a gradient elution of methanol and 0.01% ammoniated aqueous solution. Detection was performed in negative electrospray ionization (ESI<jats:sup>-<\/jats:sup>) mode with targeted single ion monitoring (Targeted-SIM) scanning, utilizing pentachlorophenol-<jats:sup>13<\/jats:sup>C<jats:sub>6<\/jats:sub> (PCP-<jats:sup>13<\/jats:sup>C<jats:sub>6<\/jats:sub>) as an isotopically labeled internal standard. The method exhibited excellent linearity across a concentration range of 1.0\u2013500.0 \u03bcg\/L (R<jats:sup>2<\/jats:sup>\u2009\u2265\u20090.999), with a limit of detection (LOD) of 0.5 \u03bcg\/kg and a limit of quantification (LOQ) of 1.5 \u03bcg\/kg. Validation studies at three spiking levels (20.0, 200.0, and 400.0 \u03bcg\/kg) demonstrated satisfactory recoveries of 97.2%\u201399.7% and precision with relative standard deviations (RSDs) of 0.8%\u20131.7% (n\u2009=\u20096). The total chromatographic runtime was optimized to 6 minutes. Application of this method to Seventy-five commercial cutting boards revealed PCP-Na residues in five samples, with concentrations ranging from 1.3 to 416\u2009mg\/kg. This approach features streamlined sample preparation, high sensitivity, robust accuracy, and rapid analysis, making it particularly suitable for routine monitoring of PCP-Na residues in bamboo and wooden food contact materials.<\/jats:p>","DOI":"10.1371\/journal.pone.0326129","type":"journal-article","created":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T17:33:33Z","timestamp":1750095213000},"page":"e0326129","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Rapid determination of sodium pentachlorophenate in bamboo and wooden cutting boards via ultrasonic-assisted liquid-liquid extraction coupled with ultra-performance liquid chromatography-high resolution mass spectrometry"],"prefix":"10.1371","volume":"20","author":[{"given":"Ye","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingyou","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5767-2027","authenticated-orcid":true,"given":"Guojian","family":"Shao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2025,6,16]]},"reference":[{"issue":"4","key":"pone.0326129.ref001","doi-asserted-by":"crossref","first-page":"368504241300638","DOI":"10.1177\/00368504241300638","article-title":"Development 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