{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T04:07:58Z","timestamp":1750910878829,"version":"3.41.0"},"reference-count":40,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T00:00:00Z","timestamp":1750809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Diputaci\u00f3 de Lleida","award":["4R23\/364"],"award-info":[{"award-number":["4R23\/364"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec014\">\n<jats:title>Objectives<\/jats:title>\n<jats:p>We analyzed the subtypes of arterial hypertension and their relationship with different comorbidities and ethnicity during pregnancy.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec015\">\n<jats:title>Study design<\/jats:title>\n<jats:p>This is a retrospective observational cohort study in 17,177 pregnant women during the years 2012\u20132018 in the health region of Lleida.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec016\">\n<jats:title>Main outcome measures<\/jats:title>\n<jats:p>We analyzed the relationship of chronic hypertension, gestational hypertension, and pre-eclampsia with different variables, including comorbidities, vascular risk factors, and ethnicity. We calculated the adjusted odds ratio (OR) and the 95% confidence interval (CI) with multivariate logistic regression models.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec017\">\n<jats:title>Results<\/jats:title>\n<jats:p>The total prevalence of arterial hypertension among pregnant women was 3.10%; of these, 1.53% had chronic hypertension, 0.65% had gestational hypertension, and 0.78% had pre-eclampsia. Superimposed pre-eclampsia on chronic hypertension occurred in 25 cases (0.14%). Chronic hypertension was associated with age (OR = 1.07), overweight (OR = 4.32), obesity (OR = 2.11), diabetes mellitus (OR = 2.38), hypothyroidism (OR = 2.23), and sub-Saharan origin (OR = 3.36). Gestational hypertension was correlated with age (OR = 1.06), overweight (OR = 5.84), obesity (OR = 1.89), and Asian\/Middle Eastern origin (OR = 3.71). Finally, pre-eclampsia was associated with overweight (OR = 2.37) and Sub-Saharan Africa origin (OR = 2.45).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec018\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Pregnant women with hypertension may benefit from the knowledge of the subtype and a consequent coordinated prenatal and pregnancy approach.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0326649","type":"journal-article","created":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T17:41:26Z","timestamp":1750873286000},"page":"e0326649","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Subtypes of hypertension and their association to comorbidities and ethnicity in pregnant women"],"prefix":"10.1371","volume":"20","author":[{"given":"Daniel","family":"Perej\u00f3n L\u00f3pez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0923-5943","authenticated-orcid":true,"given":"Nancy Melissa","family":"Medrano Duarte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Catalina","family":"Serna Arn\u00e1iz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam","family":"Or\u00f3s Ruiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00falia","family":"Siscart Viladegut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I\u00f1aki","family":"Gasc\u00f3 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