{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T04:15:15Z","timestamp":1751516115888,"version":"3.41.0"},"reference-count":86,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:00:00Z","timestamp":1751414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"crossref","award":["192124"],"award-info":[{"award-number":["192124"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"name":"CAN-TAP-TALENT","award":["184898"],"award-info":[{"award-number":["184898"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>Understanding disparities in the prevalence of Post COVID-19 Condition (PCC) amongst vulnerable populations is crucial to improving care and addressing intersecting inequities. This study aims to develop a comprehensive framework for integrating social determinants of health (SDOH) into PCC research by leveraging natural language processing (NLP) techniques to analyze disparities and variations in SDOH representation within PCC case reports. Following construction of a PCC Case Report Corpus, comprising over 7,000 case reports from the LitCOVID repository, a subset of 709 reports were annotated with 26 core SDOH-related entity types using pre-trained named entity recognition (NER) models, human review, and data augmentation to improve quality, diversity and representation of entity types. An NLP pipeline integrating NER, natural language inference (NLI), trigram and frequency analyses was developed to extract and analyze these entities. Both encoder-only transformer models and RNN-based models were assessed for the NER objective.<\/jats:p>\n<jats:p>Fine-tuned encoder-only BERT models outperformed traditional RNN-based models in generalizability to distinct sentence structures and greater class sparsity, achieving a macro F1-score of 0.72 and macro AUC of 0.99 on a held-out generalization set. Exploratory analysis revealed variability in entity richness, with prevalent entities like condition, age, and access to care, and under-representation of sensitive categories like race and housing status. Trigram analysis highlighted frequent co-occurrences among entities, including age, gender, and condition. The NLI objective (entailment and contradiction analysis) showed attributes like \u201cExperienced violence or abuse\u201d and \u201cHas medical insurance\u201d had high entailment rates (82.4%\u201380.3%), while attributes such as \u201cIs female-identifying,\u201d \u201cIs married,\u201d and \u201cHas a terminal condition\u201d exhibited high contradiction rates (70.8%\u201398.5%).<\/jats:p>\n<jats:p>Our results highlight the effectiveness of transformer-based NER in extracting SDOH information from case reports. However, the findings also expose critical gaps in the representation of marginalized groups within PCC-related academic case reports, e.g., across gender, insurance status, and age. This work underscores the need for standardized SDOH documentation and inclusive reporting practices to enable more equitable research and inform future health policy and AI model development.<\/jats:p>","DOI":"10.1371\/journal.pone.0326668","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T17:48:03Z","timestamp":1751478483000},"page":"e0326668","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Academic case reports lack diversity: Assessing the presence and diversity of sociodemographic and behavioral factors related to Post COVID-19 Condition"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-6051-4026","authenticated-orcid":true,"given":"Juan Andres","family":"Medina Florez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaina","family":"Raza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3031-7695","authenticated-orcid":true,"given":"Rashida","family":"Lynn Ansell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahra","family":"Shakeri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brendan T.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2236-2611","authenticated-orcid":true,"given":"Elham","family":"Dolatabadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2025,7,2]]},"reference":[{"key":"pone.0326668.ref001","doi-asserted-by":"crossref","first-page":"101019","DOI":"10.1016\/j.eclinm.2021.101019","article-title":"Characterizing long COVID in an international cohort: 7 months of symptoms and their impact","volume":"38","author":"HE Davis","year":"2021","journal-title":"EClinicalMedicine"},{"issue":"3","key":"pone.0326668.ref002","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/s41579-022-00846-2","article-title":"Long COVID: major findings, mechanisms and recommendations","volume":"21","author":"HE Davis","year":"2023","journal-title":"Nat Rev Microbiol"},{"key":"pone.0326668.ref003","article-title":"Using social media to help understand patient-reported health outcomes of Post-COVID-19 condition: natural language processing approach","volume":"25","author":"E Dolatabadi","year":"2023","journal-title":"J Med Internet Res"},{"key":"pone.0326668.ref004","unstructured":"Post COVID-19 condition (Long COVID). https:\/\/www.who.int\/europe\/news-room\/fact-sheets\/item\/post-COVID-19-condition. 2023."},{"key":"pone.0326668.ref005","unstructured":"CDC. 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