{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T06:31:42Z","timestamp":1770445902518,"version":"3.49.0"},"reference-count":14,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T00:00:00Z","timestamp":1751932800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>Peritoneal dialysis (PD) is an effective renal replacement strategy for patients with end-stage renal disease utilizing the peritoneum as the filter and PD catheter as access. A survey of PD patients showed that some felt uncomfortable with the length of current catheters and would be interested to explore newer, shorter designs. We redesigned the transfer set and external portion of the catheter, addressing this barrier as a part of our multi-institutional design project led by a nephrologist from the University of Arkansas for Medical Sciences (UAMS) and an engineering design team from the biomedical engineering department at the University of Arkansas. Multiple designs were considered, including spiral, retractable, and collapsible bulbs, with an accordion-style mechanism being selected for prototyping. We created several prototypes, first by 3D printing as well as by silicone casting. Computational fluid analysis showed the design to be fully capable of delivering clinically relevant flows. The final design of our PD transfer set has a flexible accordion section that is 7\u2009cm when extended and collapses to substantially shorten this length. We propose that the design can also be extended to the extra-abdominal section of the PD catheter.<\/jats:p>","DOI":"10.1371\/journal.pone.0326921","type":"journal-article","created":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T13:34:46Z","timestamp":1751981686000},"page":"e0326921","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Addressing the barriers to peritoneal dialysis\u2014Visual appeal matters"],"prefix":"10.1371","volume":"20","author":[{"given":"Sam","family":"Stephens","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larissa","family":"Whale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makenzie","family":"Kapales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatima","family":"Ayub","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morten O.","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6014-1337","authenticated-orcid":true,"given":"Manisha","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2025,7,8]]},"reference":[{"issue":"9155","key":"pone.0326921.ref001","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/S0140-6736(98)09410-0","article-title":"Peritoneal dialysis","volume":"353","author":"R Gokal","year":"1999","journal-title":"Lancet"},{"issue":"4","key":"pone.0326921.ref002","doi-asserted-by":"crossref","first-page":"343","DOI":"10.37526\/1526-744X.2020.47.4.343","article-title":"The peritoneal dialysis transfer set replacement procedure","volume":"47","author":"I Funes","year":"2020","journal-title":"Nephrol Nurs J"},{"issue":"1","key":"pone.0326921.ref003","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5414\/CN108382","article-title":"Peritoneal dialysis: update on patient survival","volume":"83","author":"JP Teixeira","year":"2014","journal-title":"Clin Nephrol"},{"key":"pone.0326921.ref004","first-page":"447","article-title":"Evaluating the benefits of home-based peritoneal dialysis","volume":"7","author":"K Fran\u00e7ois","year":"2014","journal-title":"Int J Nephrol Renovasc Dis"},{"key":"pone.0326921.ref005","doi-asserted-by":"crossref","DOI":"10.1177\/089686080902902S11","article-title":"Clinical advantages of peritoneal dialysis","volume":"29","author":"B Tokgoz","year":"2009","journal-title":"Perit Dial Int"},{"issue":"10","key":"pone.0326921.ref006","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.2215\/CJN.11241012","article-title":"Neighborhood socioeconomic status and barriers to peritoneal dialysis: a mixed methods study","volume":"8","author":"S Prakash","year":"2023","journal-title":"Clin J Am Soc Nephrol"},{"key":"pone.0326921.ref007","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/B978-1-4557-4096-3.00003-9","article-title":"Chapter 3 - Chronic Kidney Failure: Renal Replacement Therapy.","volume-title":"Kidney Transplantation\u2013Principles and Practice","author":"A. Davenport","year":"2014"},{"issue":"3","key":"pone.0326921.ref008","doi-asserted-by":"crossref","first-page":"698","DOI":"10.3934\/publichealth.2023048","article-title":"Body image, emotional intelligence and quality of life in peritoneal dialysis patients","volume":"10","author":"E Marki","year":"2023","journal-title":"AIMS Public Health"},{"issue":"42","key":"pone.0326921.ref009","doi-asserted-by":"crossref","first-page":"8636","DOI":"10.1039\/C8SM01355A","article-title":"Overcurvature induced multistability of linked conical frusta: how a \u201cbendy straw\u201d holds its shape","volume":"14","author":"NP Bende","year":"2018","journal-title":"Soft Matter"},{"issue":"8","key":"pone.0326921.ref010","doi-asserted-by":"crossref","first-page":"515","DOI":"10.3390\/coatings9080515","article-title":"Fused deposition modelling as a potential tool for antimicrobial dialysis catheters manufacturing: new trends vs. conventional approaches","volume":"9","author":"E Mathew","year":"2019","journal-title":"Coatings"},{"issue":"2","key":"pone.0326921.ref011","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1021\/acsmacrolett.2c00701","article-title":"Biomedical Silicones: Leveraging Additive Strategies to Propel Modern Utility","volume":"12","author":"AC Marmo","year":"2023","journal-title":"ACS Macro Lett"},{"issue":"1","key":"pone.0326921.ref012","article-title":"Measurement of hydrostatic intraperitoneal pressure: a necessary routine test in peritoneal dialysis","volume":"16","author":"PY Durand","year":"1996","journal-title":"Perit Dial Int"},{"issue":"6","key":"pone.0326921.ref013","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.nefro.2017.05.014","article-title":"Intraperitoneal pressure in peritoneal dialysis","volume":"37","author":"V P\u00e9rez D\u00edaz","year":"2017","journal-title":"Nefrologia"},{"key":"pone.0326921.ref014","unstructured":"Insights FB. Peritoneal dialysis market size, share and industry growth by product type (CAPD, APD), product (cyclers, fluids), end user (home health care and hospitals) and regional forecast, 2018 - 2032. 2024."}],"container-title":["PLOS One"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0326921","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T13:34:52Z","timestamp":1751981692000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0326921"}},"subtitle":[],"editor":[{"given":"Ankur","family":"Shah","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,7,8]]},"references-count":14,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2025,7,8]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0326921","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,8]]}}}