{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T04:42:13Z","timestamp":1785386533224,"version":"3.55.0"},"reference-count":37,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T00:00:00Z","timestamp":1751241600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"The Construction of Key Public Health Disciplines and Laboratories in Jiulongpo District, Chongqing, China","award":["JLPWBF2023063"],"award-info":[{"award-number":["JLPWBF2023063"]}]},{"name":"The 2024 Science and Technology Plan Projects of Jiulongpo District, Chongqing Municipality (Jointly Implemented by the Science and Health Sectors).","award":["2024-04-009-Z"],"award-info":[{"award-number":["2024-04-009-Z"]}]},{"name":"The 2024 Science and Technology Plan Projects of Jiulongpo District, Chongqing Municipality (Jointly Implemented by the Science and Health Sectors).","award":["2024-04-009-Z"],"award-info":[{"award-number":["2024-04-009-Z"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec017\">\n<jats:title>Background<\/jats:title>\n<jats:p>The prevalence of Alzheimer\u2019s disease (AD) continues to rise as the aging population increases, and the resulting cognitive decline severely affects patients\u2019 quality of life. However, the public\u2019s understanding of AD is markedly insufficient, which limits the effectiveness of early prevention and treatment. This study conducted a cross-sectional survey to assess the level of knowledge about AD among adult residents in Jiulongpo District, Chongqing, as well as their attitudes towards people with dementia, providing a basis for formulating targeted intervention strategies.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec018\">\n<jats:title>Methods<\/jats:title>\n<jats:p>A cross-sectional survey was conducted in Jiulongpo, Chongqing, China, from September to October 2024. The self-reported questionnaire for participants included three parts: demographic information, the Alzheimer\u2019s Disease Knowledge Scale (ADKS), and the Dementia Attitude Scale (DAS). Multiple linear regression analysis was used to identify the main factors influencing AD knowledge and attitudes.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec019\">\n<jats:title>Results<\/jats:title>\n<jats:p>1,362 respondents were surveyed, with 64.24% female. The age group of 40\u201364 has the largest number of people, accounting for 38.03%. The average ADKS score was 17.67 (standard deviation\u2009=\u20092.47), with individual item score rates ranging from 16.01% to 89.72% across the 30 items. The domains with the lowest ADKS score rates were \u201cCaregiving\u201d (43.40%) and \u201cSymptoms\u201d (52.25%). The average score on the DAS was 81.72 (standard deviation\u2009=\u200911.19). The score rates for the \u201cDementia knowledge,\u201d \u201cPositive social comfort,\u201d and \u201cNegative social comfort\u201d dimensions of the DAS were 61.56%, 55.02%, and 56.38%, respectively. Residents aged 18\u201339, living in urban areas, with higher education or above, working in healthcare, having a higher income level, being unmarried, and having experience in Alzheimer\u2019s Disease and Related Dementias (ADRD) knowledge training have a higher level of knowledge about AD and a more positive attitude towards it. Residents with family members suffering from ADRD have lower DAS scores than those without such family members.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec020\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>People\u2019s understanding of AD is limited, especially in the areas of \u201cCaregiving\u201d and \u201cSymptoms\u201d, and they hold a neutral attitude toward dementia. We recommend intensifying health education efforts on AD knowledge across different populations, particularly emphasizing the promotion of knowledge in weak areas, while also cultivating their friendly attitudes towards dementia patients.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0327346","type":"journal-article","created":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T17:32:37Z","timestamp":1751304757000},"page":"e0327346","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Knowledge and attitudes towards Alzheimer\u2019s disease among adult residents in Jiulongpo, Chongqing, China: A cross-sectional survey"],"prefix":"10.1371","volume":"20","author":[{"given":"Jinhua","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4669-2171","authenticated-orcid":true,"given":"Tong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,6,30]]},"reference":[{"issue":"11","key":"pone.0327346.ref001","doi-asserted-by":"crossref","first-page":"3777","DOI":"10.3390\/ijerph17113777","article-title":"Relationship between Knowledge and Types of Attitudes towards People Living with Dementia","volume":"17","author":"C-Y Chang","year":"2020","journal-title":"Int J Environ Res Public Health"},{"key":"pone.0327346.ref002","author":"ADI"},{"issue":"1","key":"pone.0327346.ref003","doi-asserted-by":"crossref","first-page":"010317","DOI":"10.7189\/jogh.09.010317","article-title":"Neuropsychological assessment in preclinical and prodromal Alzheimer disease: a global perspective","volume":"9","author":"T Watermeyer","year":"2019","journal-title":"J Glob Health"},{"issue":"12","key":"pone.0327346.ref004","article-title":"Prevalence, risk factors, and management of dementia and mild cognitive impairment in adults aged 60 years or older in China: a cross-sectional study","volume":"5","author":"L Jia","year":"2020","journal-title":"Lancet Public Health"},{"key":"pone.0327346.ref005","unstructured":"Alzheimer\u2019s Disease International. World alzheimer report 2021: journey through the diagnosis of dementia. 2021."},{"issue":"1","key":"pone.0327346.ref006","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1186\/s12877-018-0821-4","article-title":"Community health professionals\u2019 dementia knowledge, attitudes and care approach: a cross-sectional survey in Changsha, China","volume":"18","author":"Y Wang","year":"2018","journal-title":"BMC Geriatr"},{"key":"pone.0327346.ref007","doi-asserted-by":"crossref","first-page":"4161","DOI":"10.7189\/jogh.14.04161","article-title":"Heterogeneity in the level of dementia literacy among community doctors in China: a latent profile analysis","volume":"14","author":"S Qiu","year":"2023","journal-title":"J Glob Health"},{"issue":"1","key":"pone.0327346.ref008","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1186\/s12909-020-02365-1","article-title":"A comparative study of dementia knowledge, attitudes and care approach among Chinese nursing and medical students","volume":"20","author":"Y Wang","year":"2020","journal-title":"BMC Med Educ"},{"issue":"9","key":"pone.0327346.ref009","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1111\/jpm.12259","article-title":"A study on knowledge, attitudes and health behaviours regarding Alzheimer\u2019s disease among community residents in Tianjin, China","volume":"22","author":"H-F Yang","year":"2015","journal-title":"J Psychiatr Ment Health Nurs"},{"issue":"10","key":"pone.0327346.ref010","doi-asserted-by":"crossref","first-page":"6972","DOI":"10.1002\/nop2.1952","article-title":"Alzheimer\u2019s disease knowledge of nursing staff in East China: A latent profile analysis","volume":"10","author":"S Zuo","year":"2023","journal-title":"Nurs Open"},{"key":"pone.0327346.ref011","first-page":"273","article-title":"Investigation on the social awareness of Alzheimer\u2019s disease-based on the social survey in Zhenjiang city","volume":"32","author":"S Liang","year":"2024","journal-title":"Chin 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Hakami","year":"2023","journal-title":"Cureus"},{"issue":"2","key":"pone.0327346.ref015","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1093\/geront\/gnp023","article-title":"The Alzheimer\u2019s Disease Knowledge Scale: development and psychometric properties","volume":"49","author":"BD Carpenter","year":"2009","journal-title":"Gerontologist"},{"key":"pone.0327346.ref016","article-title":"Reliability and validity of the chinese version of the alzheimer\u2019s disease knowledge scale","author":"R He","year":"2013","journal-title":"Chin J Nurs"},{"key":"pone.0327346.ref017","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4061\/2010\/454218","article-title":"Development and psychometric validation of the dementia attitudes scale","volume":"2010","author":"ML O\u2019Connor","year":"2010","journal-title":"Int J Alzheimers Dis"},{"key":"pone.0327346.ref018","first-page":"1791","article-title":"Adaptation and validation of Dementia Attitudes Scale to Chinese community 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Dr"},{"key":"pone.0327346.ref022","doi-asserted-by":"crossref","first-page":"23779608231201052","DOI":"10.1177\/23779608231201052","article-title":"Jordanian Community People\u2019s Knowledge of and Attitudes Toward Dementia","volume":"9","author":"A Abdalrahim","year":"2023","journal-title":"SAGE Open Nurs"},{"issue":"1","key":"pone.0327346.ref023","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1186\/s12877-022-03389-6","article-title":"Undergraduate nursing students\u2019 knowledge of and attitudes toward people with alzheimer\u2019s disease","volume":"22","author":"M Aljezawi","year":"2022","journal-title":"BMC Geriatr"},{"key":"pone.0327346.ref024","doi-asserted-by":"crossref","first-page":"4213","DOI":"10.2147\/JMDH.S443189","article-title":"The Mediating Role of Attitudes Towards Dementia on the Relationship Between Dementia Knowledge and Behaviors Towards Persons with Dementia: A Cross-Sectional Study","volume":"16","author":"Y-T Li","year":"2023","journal-title":"J Multidiscip Healthc"},{"issue":"5","key":"pone.0327346.ref025","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1080\/10401334.2021.1971988","article-title":"Knowledge and Attitudes toward Dementia among Undergraduate Health Professional Students in China: A Cross-Sectional Survey","volume":"34","author":"A Dong","year":"2022","journal-title":"Teach Learn Med"},{"issue":"1","key":"pone.0327346.ref026","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1186\/s12877-023-03914-1","article-title":"Experiences of caregiving with Alzheimer\u2019s disease in the LGBT community","volume":"23","author":"C Candrian","year":"2023","journal-title":"BMC Geriatr"},{"issue":"3","key":"pone.0327346.ref027","doi-asserted-by":"crossref","first-page":"136","DOI":"10.34172\/jcs.2023.33098","article-title":"Experiences of Family Caregivers Caring for Patient with Alzheimer\u2019s Disease: A Hermeneutic Phenomenological Study","volume":"12","author":"EH Tambunan","year":"2023","journal-title":"J Caring Sci"},{"issue":"1","key":"pone.0327346.ref028","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s12877-023-03735-2","article-title":"Examining the association between neuropsychiatric symptoms among people with dementia and caregiver mental health: are caregiver burden and affiliate stigma mediators?","volume":"23","author":"Y-J Chen","year":"2023","journal-title":"BMC Geriatr"},{"key":"pone.0327346.ref029","unstructured":"Yu X. Health education of patients with alzheimer disease in different periods. 2006."},{"issue":"1","key":"pone.0327346.ref030","doi-asserted-by":"crossref","first-page":"189","DOI":"10.3233\/ADR-230108","article-title":"Understanding the Perspectives and Needs of Latinx Caregivers of Persons with Alzheimer\u2019s Disease in the Appalachians: An Interpretive Phenomenological Approach","volume":"8","author":"A Moore","year":"2024","journal-title":"J Alzheimers Dis Rep"},{"key":"pone.0327346.ref031","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1111\/jocn.15451","article-title":"Healthcare professionals\u2019 dementia knowledge and attitudes towards dementia care and family carers\u2019 perceptions of dementia care in China: An integrative review","volume":"31","author":"W Zhao","year":"2022","journal-title":"J Clin Nurs"},{"key":"pone.0327346.ref032","article-title":"Investigation of the Current Status of Clinical Nurses\u2019 Knowledge and Attitudes towards Senile Dementia","author":"W Feilong","year":"2017","journal-title":"Nurs J Chin Peoples Lib Army"},{"key":"pone.0327346.ref033","doi-asserted-by":"crossref","unstructured":"Shi L, Qiu H, Zhou M, Wang W. The prevalence of mild cognitive impairment among the elderly population based on spatio-temporal data in the Yangtze River delta region of China. 2021.","DOI":"10.21203\/rs.3.rs-579285\/v1"},{"issue":"1","key":"pone.0327346.ref034","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1186\/s12889-020-08953-6","article-title":"Attitude, practice and its associated factors towards Diabetes complications among type 2 diabetic patients at Addis Zemen District hospital, Northwest Ethiopia","volume":"20","author":"Y Belsti","year":"2020","journal-title":"BMC Public Health"},{"key":"pone.0327346.ref035","article-title":"Knowledge and attitude towards Alzheimer\u2019s disease and related dementias in a low- to middle-income country: a cross-sectional survey among Lebanese middle-aged and older adults","volume":"21","author":"M Elbejjani","year":"2021","journal-title":"Psychogeriatr Off Jpn Psychogeriatr Soc"},{"key":"pone.0327346.ref036","article-title":"Public awareness of Alzheimer\u2019s disease: A cross-sectional study from Saudi Arabia","volume":"15","author":"A Nm","year":"2022","journal-title":"Int J Gen Med"},{"issue":"6","key":"pone.0327346.ref037","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1177\/1471301218805923","article-title":"Public knowledge of late-life cognitive decline and dementia in an international sample","volume":"19","author":"R Van Patten","year":"2020","journal-title":"Dementia (London)"}],"container-title":["PLOS One"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0327346","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T17:32:45Z","timestamp":1751304765000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0327346"}},"subtitle":[],"editor":[{"given":"Modupe","family":"Akintomide","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,6,30]]},"references-count":37,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,6,30]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0327346","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,30]]}}}