{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:14:52Z","timestamp":1787170492702,"version":"build-2736575974"},"reference-count":26,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T00:00:00Z","timestamp":1755475200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"\n Objective<\/jats:title>\n The objective of this scoping review is to describe and assess what cancer treatment interventions exist for forcibly displaced populations living with cancer in LMIC humanitarian settings in the Middle East and North African (MENA) region and what research has been done on these interventions.<\/jats:p>\n <\/jats:sec>\n \n Background<\/jats:title>\n Humanitarian aid usually provides short-term requirements for food, shelter, and trauma relief; long-term relief focuses mainly on communicable diseases and not non-communicable diseases (NCDs) like cancer. However, no systematic search and synthesis resource of existing cancer care interventions for forcibly displaced populations in LMICs of the MENA region exists.<\/jats:p>\n <\/jats:sec>\n \n Inclusion criteria<\/jats:title>\n Original studies will be included on interventions for all types of cancer which are available to support forcibly displaced populations in settings of humanitarian crisis in Djibouti, Egypt, Jordan, Lebanon, Mauritania, occupied Palestinian Territories, Somalia, Sudan, South Sudan, Syria, and Yemen.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A scoping review will be conducted in accordance with JBI methods and guidelines and PRISMA reporting guidelines (\n S3 Appendix<\/jats:bold>\n ). PubMed, Global Health, Embase, Scopus, The Lens, Global Index Medicus, and CINAHL Complete will be searched for peer-reviewed articles published from January to until present. IOM, ReliefWeb, OSCE, UNHCR, WHO, OCHA, and ACLED will be searched for grey literature. A dual review using three reviewers will independently identify all relevant articles and extract data from them. A narrative summary of findings will be reported,\n <\/jats:p>\n <\/jats:sec>\n \n Discussion<\/jats:title>\n This scoping review will provide an overview of the available cancer interventions for forcibly displaced populations and describe the research done regarding these interventions. Potential gaps in the field will be identified,<\/jats:p>\n <\/jats:sec>\n \n Systematic Review Registration<\/jats:title>\n \n Zenodo,\n https:\/\/doi.org\/10.5281\/zenodo.14633092<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1371\/journal.pone.0327946","type":"journal-article","created":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T17:30:37Z","timestamp":1755538237000},"page":"e0327946","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cancer care interventions for forcibly displaced populations in low- and middle-income countries of the Middle East and North African region affected by humanitarian crises: Protocol for a scoping review"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-6294-9591","authenticated-orcid":true,"given":"Anne Lyon","family":"Havlik","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zena","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippa Susan","family":"Chadwick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Nyhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaveh","family":"Khoshnood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,8,18]]},"reference":[{"key":"pone.0327946.ref001","unstructured":"Humanitarian Coalition. What is a humanitarian emergency?. https:\/\/www.humanitariancoalition.ca\/what-is-a-humanitarian-emergency. 2021. 2025 January 27."},{"key":"pone.0327946.ref002","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1007\/978-3-030-36811-1_215","article-title":"Cancer Care in Low- and Middle-Income Countries Affected by Humanitarian Crises","author":"J Alawa","year":"2021","journal-title":"Handbook of Healthcare in the Arab World. Springer International Publishing"},{"issue":"6","key":"pone.0327946.ref003","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2019-001870","article-title":"Health research in humanitarian crises: an urgent global imperative","volume":"4","author":"BA Kohrt","year":"2019","journal-title":"BMJ Glob Health"},{"key":"pone.0327946.ref004","unstructured":"World Bank. By the numbers: the cost of war & peace in the Middle East. https:\/\/www.worldbank.org\/en\/news\/feature\/2016\/02\/03\/by-the-numbers-the-cost-of-war-and-peace-in-mena. 2016. 2025 January 27."},{"key":"pone.0327946.ref005","unstructured":"UNHCR. UNHCR Global Trends: Forced Displacement in 2018. 2019. https:\/\/reliefweb.int\/report\/world\/unhcr-global-trends-forced-displacement-2018-0"},{"key":"pone.0327946.ref006","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1200\/EDBK_201365","article-title":"Cancer Care for Refugees and Displaced Populations: Middle East Conflicts and Global Natural Disasters","volume":"38","author":"NS El Saghir","year":"2018","journal-title":"Am Soc Clin Oncol Educ Book"},{"key":"pone.0327946.ref007","unstructured":"US Global Leadership Coalition. NCD care in a crisis. https:\/\/www.usglc.org\/global-impact-project\/stories\/ncd-care-in-a-crisis\/. 2018. 2025 January 27."},{"key":"pone.0327946.ref008","unstructured":"UNHCR, IRC, Informal Inter-Agency Group on NCDs in Humanitarian Settings. Integrating non-communicable disease care in humanitarian settings: an operational guide. 2020. https:\/\/reliefweb.int\/report\/world\/integrating-non-communicable-disease-care-humanitarian-settings-operational-guide"},{"key":"pone.0327946.ref009","unstructured":"OECD. Crises in middle income countries: World humanitarian summit. 2018. https:\/\/www.oecd.org\/development\/humanitarian-donors\/docs\/Crises_in_middle_Income_Countries_OECD_guideline.pdf"},{"issue":"9","key":"pone.0327946.ref010","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0222496","article-title":"\u201cIf I have a cancer, it is not my fault I am a refugee\u201d: A qualitative study with expert stakeholders on cancer care management for Syrian refugees in Jordan","volume":"14","author":"M Marzouk","year":"2019","journal-title":"PLoS One"},{"issue":"4","key":"pone.0327946.ref011","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1200\/JGO.2016.006189","article-title":"Cancer Care at Times of Crisis and War: The Syrian Example","volume":"3","author":"E Sahloul","year":"2016","journal-title":"J Glob Oncol"},{"key":"pone.0327946.ref012","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1200\/JGO.19.00281","article-title":"High-Cost Cancer Treatment Across Borders in Conflict Zones: Experience of Iraqi Patients in Lebanon","volume":"6","author":"M Skelton","year":"2020","journal-title":"JCO Glob Oncol"},{"key":"pone.0327946.ref013","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.3332\/ecancer.2020.1018","article-title":"Cancer care in times of conflict: cross border care in Pakistan of patients from Afghanistan","volume":"14","author":"MA Yusuf","year":"2020","journal-title":"Ecancermedicalscience"},{"issue":"4","key":"pone.0327946.ref014","first-page":"318","article-title":"Principles and practice of screening for disease","volume":"16","author":"JMG Wilson","year":"1968","journal-title":"J R Coll Gen Pract"},{"issue":"1","key":"pone.0327946.ref015","first-page":"653","article-title":"Health research priorities in the Middle East and North Africa region: a systematic review","volume":"20","author":"N El Achi","year":"2020","journal-title":"BMC Public Health"},{"key":"pone.0327946.ref016","unstructured":"World Bank Group. List of fragile and conflict-affected situations (FY20\u2013). https:\/\/thedocs.worldbank.org\/en\/doc\/9b8fbdb62f7183cef819729cc9073671-0090082022\/original\/FCSList-FY06toFY22.pdf. 2025 January 27."},{"key":"pone.0327946.ref017","unstructured":"UNICEF. The situation of children in the State of Palestine. 2022. https:\/\/www.unicef.org\/mena\/media\/19901\/file"},{"key":"pone.0327946.ref018","unstructured":"ReliefWeb. Informing humanitarians worldwide. https:\/\/reliefweb.int\/. 2023. 2025 June 4."},{"key":"pone.0327946.ref019","unstructured":"World Bank Group. Historical overview: the World Bank Group\u2019s classification of fragile and conflict affected situations. https:\/\/thedocs.worldbank.org\/en\/doc\/373511582764863285-0090022020\/original\/FCSHistorialnote.pdf. 2020. 2025 January 27."},{"key":"pone.0327946.ref020","unstructured":"Inform Severity Index. https:\/\/www.acaps.org\/en\/data#dataset-3. 2021. 2025 June 4."},{"key":"pone.0327946.ref021","year":"2024"},{"key":"pone.0327946.ref022","doi-asserted-by":"crossref","unstructured":"Aromataris E, Munn Z. JBI Manual for Evidence Synthesis. https:\/\/jbi-global-wiki.refined.site\/space\/MANUAL. 2025 January 27.","DOI":"10.46658\/JBIMES-24-01"},{"issue":"7","key":"pone.0327946.ref023","doi-asserted-by":"crossref","first-page":"467","DOI":"10.7326\/M18-0850","article-title":"PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation","volume":"169","author":"AC Tricco","year":"2018","journal-title":"Ann Intern Med"},{"key":"pone.0327946.ref024","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"MJ Page","year":"2021","journal-title":"BMJ"},{"issue":"3","key":"pone.0327946.ref025","doi-asserted-by":"crossref","first-page":"520","DOI":"10.11124\/JBIES-22-00123","article-title":"Recommendations for the extraction, analysis, and presentation of results in scoping reviews","volume":"21","author":"D Pollock","year":"2023","journal-title":"JBI Evid Synth"},{"key":"pone.0327946.ref026","unstructured":"Evidence Aid. About us. https:\/\/evidenceaid.org\/who-we-are. 2025 January 27."}],"container-title":["PLOS One"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0327946","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T17:30:41Z","timestamp":1755538241000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0327946"}},"subtitle":[],"editor":[{"given":"Che Matthew","family":"Harris","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,8,18]]},"references-count":26,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2025,8,18]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0327946","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,18]]}}}