{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T19:17:10Z","timestamp":1792264630856,"version":"4.4.0"},"reference-count":48,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T00:00:00Z","timestamp":1754265600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Introduction<\/jats:title>\n<jats:p>Palliative care is a crucial component of end-stage disease management, but its utilization remains low in low- and middle-income countries, such as Ethiopia. This is due to various systemic, social, and policy barriers. Understanding these contextual factors is crucial for developing effective interventions and policy frameworks. This study aimed to explore and synthesize the barriers and facilitators to palliative care service utilization in Ethiopia using a qualitative systematic review approach.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses of Qualitative Synthesis (PRISMA-Q) guidelines, employing a qualitative systematic design. A comprehensive search was conducted across various databases using tailored keywords and MeSH terms up. The database was searched for every article published on palliative care services up to March 10, 2025, and was updated continuously until it was sent for publication. The data was extracted from March 11\u201320 and later analyzed from March 21\u201330, and the report generation till April 10, 2025. Thematic synthesis was used to analyze findings and the Grading of Recommendations Assessment, Development, and Evaluation Confidence in the Evidence from Reviews of Qualitative research approach was employed to assess the confidence of evidence.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Six studies met the inclusion criteria, encompassing diverse Ethiopian healthcare settings and stakeholders. Five major barriers were identified: policy and governance gaps, health system challenges, knowledge and training deficits, sociocultural and economic constraints, and poor collaboration. In contrast, five facilitators emerged: strong community and family support, intrinsic healthcare provider motivation, integration of palliative care into education, holistic care models, and stakeholder engagement. High confidence was assigned to four themes, underscoring their significance and applicability.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>The underutilization of palliative care in Ethiopia stems from intertwined structural, educational, and sociocultural challenges. However, promising facilitators exist that can guide policy reform and intervention design. Addressing these barriers through improved policies, workforce development, and community engagement is imperative for ensuring equitable access to quality palliative care services.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0328222","type":"journal-article","created":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T17:24:06Z","timestamp":1754328246000},"page":"e0328222","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["Barriers and facilitators to palliative care service utilization in Ethiopia: A qualitative systematic review, 2025"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-0863-4288","authenticated-orcid":true,"given":"Sadik","family":"Abdulwehab","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frezer","family":"Kedir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,8,4]]},"reference":[{"key":"pone.0328222.ref001","unstructured":"IAHPC. Palliative Care Definition - IAHPC. 2025 [cited 2025 Jun 19]. https:\/\/iahpc.org\/what-we-do\/research\/consensus-based-definition-of-palliative-care\/definition\/"},{"issue":"4","key":"pone.0328222.ref002","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/j.jpainsymman.2020.04.027","article-title":"Redefining Palliative Care\u2014A New Consensus-Based Definition","volume":"60","author":"L Radbruch","year":"2020","journal-title":"Journal of Pain and Symptom Management"},{"key":"pone.0328222.ref003","unstructured":"WHO Fact Sheet on Palliative Care. WHO takes steps to address glaring shortage of quality palliative care services. 2022 [cited 2025 Apr 13]. https:\/\/www.who.int\/news\/item\/05-10-2021-who-takes-steps-to-address-glaring-shortage-of-quality-palliative-care-services"},{"issue":"7","key":"pone.0328222.ref004","doi-asserted-by":"crossref","DOI":"10.1016\/S2214-109X(19)30172-X","article-title":"The escalating global burden of serious health-related suffering: projections to 2060 by world regions, age groups, and health conditions","volume":"7","author":"KE Sleeman","year":"2019","journal-title":"The Lancet Global Health"},{"issue":"4","key":"pone.0328222.ref005","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.jpainsymman.2020.09.036","article-title":"Estimating the number of patients receiving specialized palliative care globally in 2017","volume":"61","author":"SR Connor","year":"2021","journal-title":"J Pain Symptom 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