{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T22:21:05Z","timestamp":1788301265580,"version":"build-2803163510"},"reference-count":27,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T00:00:00Z","timestamp":1754438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"crossref","award":["2021R1A6A3A13040170"],"award-info":[{"award-number":["2021R1A6A3A13040170"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to identify caregiver-selected goal characteristics that predict functional improvements following constraint-induced movement therapy (CIMT), offering novel insights into personalized rehabilitation for younger children with unilateral cerebral palsy (UCP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study included 19 children with UCP aged 4\u20136 years who participated in a three-week CIMT program comprising 15 sessions (30 hours total), during which the unaffected hand was constrained to encourage intensive use of the affected limb. Caregivers identified five meaningful rehabilitation goals per child using the Canadian Occupational Performance Measure, categorizing them into self-care, productivity, or leisure domains and ranking them by importance. Upper-limb function was objectively evaluated using the Assisting Hand Assessment before and immediately after CIMT. Linear regression analyses identified the factors influencing goal selection, and least absolute shrinkage and selection operator regression determined whether prioritized goal types predicted improvements in upper limb function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Self-care goals were most frequently selected (72.6%), followed by leisure (26.3%) and rarely productivity (1.1%). Leisure goal selection was significantly associated with greater baseline upper limb range of motion and lower baseline occupational performance scores. The higher prioritization of goals involving quiet leisure activities (e.g., arts, crafts, computer play) and dressing tasks (e.g., buttoning, zipping) significantly predicted greater functional improvements post-intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study provides important new evidence indicating that caregiver-selected rehabilitation goals that are closely aligned with a child\u2019s latent motor capacities positively affect functional outcomes. These findings underscore the clinical importance of individualized, family-driven goal setting for optimizing therapeutic effectiveness in preschool-aged children with UCP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0329002","type":"journal-article","created":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T17:26:25Z","timestamp":1754501185000},"page":"e0329002","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Personalized goal setting and predictors of functional gains following constraint-induced movement therapy in preschool-aged children with unilateral cerebral palsy"],"prefix":"10.1371","volume":"20","author":[{"given":"Youngsub","family":"Hwang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2011-8834","authenticated-orcid":true,"given":"Jeong-Yi","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,8,6]]},"reference":[{"issue":"10","key":"pone.0329002.ref001","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1111\/dmcn.13413","article-title":"The efficacy of interventions to increase physical activity participation of children with cerebral palsy: a systematic review and meta-analysis","volume":"59","author":"S Reedman","year":"2017","journal-title":"Dev Med Child Neurol"},{"issue":"5","key":"pone.0329002.ref002","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1111\/j.1469-8749.2008.02047.x","article-title":"Prevalence, type, distribution, and severity of cerebral palsy in relation to gestational age: a meta-analytic review","volume":"50","author":"E Himpens","year":"2008","journal-title":"Dev Med Child Neurol"},{"issue":"7","key":"pone.0329002.ref003","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1038\/nrneurol.2015.97","article-title":"Rehabilitation and neuroplasticity in children with unilateral cerebral palsy","volume":"11","author":"LB Reid","year":"2015","journal-title":"Nat Rev Neurol"},{"issue":"1","key":"pone.0329002.ref004","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1177\/1545968312446950","article-title":"Neuroradiology can predict the development of hand function in children with unilateral cerebral palsy","volume":"27","author":"M Holmefur","year":"2013","journal-title":"Neurorehabil Neural Repair"},{"issue":"8","key":"pone.0329002.ref005","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1016\/j.jhsa.2008.02.032","article-title":"Hand function in cerebral palsy. 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