{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:28:26Z","timestamp":1755217706848,"version":"3.43.0"},"reference-count":32,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T00:00:00Z","timestamp":1754352000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>The parosmia, phantosmia, and anosmia test (PARPHAIT) has previously been developed as a tool for capturing quantitative and qualitative symptoms of olfactory dysfunction. Its content validity was evaluated in a patient sample, from a statistical point of view through an exploratory factor analysis, and now in a panel of experts. Based on these evaluations, we present the most recent version. The aim of this study was to evaluate the content of the novel PARPHAIT in an expert panel.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>This was a qualitative interview study with experts in the field of olfaction. The study was done in an international research community on olfactory dysfunction. Thirteen participants (mean age 49.7, 53.8% men) with expertise in the field of smell were interviewed about PARPHAIT\u2019s content, format, and applicability. Participants were selected based on their experience in the field of smell and invited to a digital interview.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Suggested improvements of PARPHAIT were provided and evaluated. Alterations were done to the formulation of items and introductory text (i.e., instructions and definitions), as well as aspects covered, and the structure and design of the questionnaire.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>PARPHAIT was considered a clear, user-friendly tool suitable for a clinical assessment context. Improvements were made based on experts\u2019 feedback, leading to a final version of the tool. However, some aspects of PARPHAIT remain open for consideration (e.g., response and scoring design) and more work remains to reach consensus on how the PARPHAIT best can capture symptoms of olfactory dysfunction.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0329108","type":"journal-article","created":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T17:27:19Z","timestamp":1754414839000},"page":"e0329108","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Experts\u2019 content validation of the parosmia, phantosmia, and anosmia test (PARPHAIT): A qualitative study"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-2222-9979","authenticated-orcid":true,"given":"Annelin","family":"Espetvedt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siri","family":"Wiig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai Victor","family":"Myrnes-Hansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8612-8384","authenticated-orcid":true,"given":"Daniel Adrian","family":"Lungu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2025,8,5]]},"reference":[{"issue":"1","key":"pone.0329108.ref001","first-page":"1","article-title":"Position paper on olfactory dysfunction","volume":"56","author":"T Hummel","year":"2016","journal-title":"Rhinology"},{"key":"pone.0329108.ref002","doi-asserted-by":"crossref","first-page":"1190994","DOI":"10.3389\/fpsyg.2023.1190994","article-title":"The assessment of qualitative olfactory dysfunction in COVID-19 patients: a systematic review of tools and their content validity","volume":"14","author":"A Espetvedt","year":"2023","journal-title":"Front Psychol"},{"key":"pone.0329108.ref003","first-page":"9","article-title":"Implementing a COVID-19 specialist smell clinic: experience at the Wrightington, Wigan and Leigh Teaching Hospitals (WWL), NHS Foundation Trust, United Kingdom","volume":"76","author":"M Chu","year":"2021","journal-title":"Med J Malaysia"},{"key":"pone.0329108.ref004","doi-asserted-by":"crossref","DOI":"10.1093\/chemse\/bjab038","article-title":"Chemosensory Dysfunctions Induced by COVID-19 Can Persist up to 7 Months: A Study of Over 700 Healthcare Workers","volume":"46","author":"N 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Dis"},{"issue":"12","key":"pone.0329108.ref010","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1001\/jamaoto.2022.3299","article-title":"Development and Psychometric Validation of the Olfactory Dysfunction Outcomes Rating","volume":"148","author":"JJ Lee","year":"2022","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"issue":"12","key":"pone.0329108.ref011","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1001\/jamaoto.2022.3392","article-title":"Development and Psychometric Validation of the Taste And Smell Tool for Evaluation (TASTE) Questionnaire","volume":"148","author":"AS Niklassen","year":"2022","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"issue":"3","key":"pone.0329108.ref012","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1002\/lary.29982","article-title":"Clinical Features of Parosmia Associated With COVID-19 Infection","volume":"132","author":"DK 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Oslo","key":"pone.0329108.ref017"},{"issue":"9","key":"pone.0329108.ref018","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1177\/1049732305276687","article-title":"Three Approaches to Qualitative Content Analysis","volume":"15","author":"HF Hsieh","year":"2005","journal-title":"Qual Health Res"},{"volume-title":"NVivo (Version 14)","year":"2024","author":"Lumivero","key":"pone.0329108.ref019"},{"key":"pone.0329108.ref020","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/0191-8869(94)90212-7","article-title":"Individual differences in sensitivity to disgust: A scale sampling seven domains of disgust elicitors","volume":"16","author":"J Haidt","year":"1994","journal-title":"Pers Individ Dif"},{"issue":"5","key":"pone.0329108.ref021","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1111\/j.1749-4486.2009.01995.x","article-title":"Psychometric validity of the 22-item Sinonasal Outcome Test","volume":"34","author":"C Hopkins","year":"2009","journal-title":"Clin Otolaryngol"},{"issue":"1","key":"pone.0329108.ref022","article-title":"A catalog of biases in questionnaires","volume":"2","author":"BCK Choi","year":"2005","journal-title":"Prev Chronic Dis"},{"key":"pone.0329108.ref023","unstructured":"Friedman HH, Herksovitz PJ, Pollack S. Biasing effects of scale-checking styles on responses to a Likert scale. In: Proceedings of the American Statistical Association Annual Conference: Survey Research Methods, 1993."},{"issue":"6","key":"pone.0329108.ref024","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1177\/00131640021970989","article-title":"Effects of Response Order on Likert-Type Scales","volume":"60","author":"L-J Weng","year":"2000","journal-title":"Educational and Psychological Measurement"},{"issue":"4","key":"pone.0329108.ref025","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1037\/pas0000648","article-title":"Does the number of response options matter? Psychometric perspectives using personality questionnaire data","volume":"31","author":"LJ Simms","year":"2019","journal-title":"Psychol Assess"},{"issue":"3","key":"pone.0329108.ref026","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s00405-004-0796-y","article-title":"Olfactory dysfunction and daily life","volume":"262","author":"J Frasnelli","year":"2005","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"12","key":"pone.0329108.ref027","article-title":"Self-reported mini olfactory questionnaire (Self-MOQ): A simple and useful measurement for the screening of olfactory dysfunction","volume":"130","author":"L-Q Zou","year":"2020","journal-title":"Laryngoscope"},{"issue":"4","key":"pone.0329108.ref028","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1080\/00016480310001411","article-title":"A Scandinavian adaptation of the Multi-Clinic Smell and Taste Questionnaire: evaluation of questions about olfaction","volume":"123","author":"S Nordin","year":"2003","journal-title":"Acta Otolaryngol"},{"issue":"8","key":"pone.0329108.ref029","doi-asserted-by":"crossref","first-page":"3695","DOI":"10.1007\/s00405-023-07893-2","article-title":"A parosmia severity index based on word-classification predicts olfactory abilities and impairment","volume":"280","author":"T H\u00f6rberg","year":"2023","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"pone.0329108.ref030","article-title":"Reliability and validity of a brief version of the Questionnaire of Olfactory Disorders (brief QOD) in patients with olfactory dysfunction","volume":"60","author":"L Zou","year":"2021","journal-title":"Rhinology"},{"issue":"4","key":"pone.0329108.ref031","first-page":"312","article-title":"Developing a core outcome set for clinical trials in olfactory disorders: a COMET initiative","volume":"61","author":"C Philpott","year":"2023","journal-title":"Rhinology"},{"issue":"3","key":"pone.0329108.ref032","doi-asserted-by":"crossref","first-page":"149","DOI":"10.32725\/jab.2024.020","article-title":"Olfactory event-related potentials (OERPs) and trigeminal event-related potentials (TERPs) in subjects after Covid-19 infection: single-center prospective study","volume":"22","author":"R Holy","year":"2024","journal-title":"J Appl Biomed"}],"container-title":["PLOS One"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0329108","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T17:27:25Z","timestamp":1754414845000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0329108"}},"subtitle":[],"editor":[{"given":"Homa","family":"Seyedmirzaei,","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,8,5]]},"references-count":32,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2025,8,5]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0329108","relation":{},"ISSN":["1932-6203"],"issn-type":[{"type":"electronic","value":"1932-6203"}],"subject":[],"published":{"date-parts":[[2025,8,5]]}}}