{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:03:01Z","timestamp":1787022181096,"version":"build-2736575974"},"reference-count":41,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:00:00Z","timestamp":1756339200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Suicide remains an ongoing public health concern, especially among adolescents. While many studies investigated the transition from ideations to attempts, they did not specifically look at the factors underlying the transition from a suicide plan to a suicide attempt, creating a vast knowledge gap. In the following study, we aim to investigate predictors of suicide attempts among adolescents with a suicide plan using data from NSDUH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We used de-identified data from consecutive cross-sectional NSDUH surveys conducted between 2015 and 2018, including respondents aged 12\u201317 who reported suicidal ideations and a plan. We performed bivariate analyses and multivariate logistic regression analyses to identify significant predictors of suicide attempts in our population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Our total sample included 3003 respondents (Population Size Estimate: 1,284,704.48). Among them, 1,780 reported suicide attempts (A) and 1,223 reported no suicide attempts (NA). The majority of adolescents in both groups were aged 15\u201317 years. More females were present in the (A) group compared to the (NA) group (p\u2009=\u20090.013). We found a positive association between antisocial behaviors and suicide attempts. Specifically, engaging in three or more antisocial behaviors significantly increased the odds of suicide attempts [adjusted odds ratio (OR) = 1.81; 95% CI = (1.11\u20132.96). Substance use and violent behaviors were also significantly associated with an increased suicide risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We found significant correlations between suicide attempts and gender, substance use disorders and engaging in antisocial behaviors. These findings underscore the importance of addressing mental health issues, substance use, and antisocial behaviors in suicide prevention efforts for at-risk adolescents.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0331261","type":"journal-article","created":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T17:31:07Z","timestamp":1756402267000},"page":"e0331261","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":4,"title":["Predictors of suicide attempts among adolescents with suicidal ideations and a plan: Results from the National Survey on Drug use and Health (NSDUH)"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4526-2595","authenticated-orcid":true,"given":"Michele","family":"Cherro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hala","family":"Itani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0160-5434","authenticated-orcid":true,"given":"Elias","family":"Ghossoub","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fadi","family":"Maalouf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,8,28]]},"reference":[{"issue":"8","key":"pone.0331261.ref001","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.5498\/wjp.v12.i8.1044","article-title":"Worldwide suicide mortality trends (2000-2019): a joinpoint regression analysis","volume":"12","author":"M Ilic","year":"2022","journal-title":"World J Psychiatry"},{"issue":"309","key":"pone.0331261.ref002","first-page":"1","article-title":"Suicide rates in the United States continue to increase","author":"H Hedegaard","year":"2018","journal-title":"NCHS Data Brief"},{"issue":"4","key":"pone.0331261.ref003","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S2215-0366(19)30030-6","article-title":"Predictors of future suicide attempt among adolescents with suicidal thoughts or non-suicidal self-harm: a population-based birth cohort study","volume":"6","author":"B Mars","year":"2019","journal-title":"Lancet Psychiatry"},{"key":"pone.0331261.ref004","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.adolescence.2019.05.008","article-title":"School environment, physical activity, and sleep as predictors of suicidal ideation in adolescents: evidence from a national survey","volume":"74","author":"CD Pfledderer","year":"2019","journal-title":"J Adolesc"},{"issue":"7","key":"pone.0331261.ref005","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1176\/ajp.2007.164.7.1035","article-title":"Columbia classification algorithm of suicide assessment (C-CASA): classification of suicidal events in the FDA\u2019s pediatric suicidal risk analysis of antidepressants","volume":"164","author":"K Posner","year":"2007","journal-title":"Am J Psychiatry"},{"key":"pone.0331261.ref006","article-title":"Suicidal ideation.","volume-title":"StatPearls","author":"B Harmer","year":"2021"},{"issue":"3","key":"pone.0331261.ref007","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1001\/2013.jamapsychiatry.55","article-title":"Prevalence, correlates, and treatment of lifetime suicidal behavior among adolescents: results from the National Comorbidity Survey Replication Adolescent Supplement","volume":"70","author":"MK Nock","year":"2013","journal-title":"JAMA Psychiatry"},{"issue":"9","key":"pone.0331261.ref008","doi-asserted-by":"crossref","first-page":"4152","DOI":"10.1017\/S0033291722000836","article-title":"Association of childhood bullying victimisation with suicide deaths: findings from a 50-year nationwide cohort study","volume":"53","author":"MC Geoffroy","year":"2023","journal-title":"Psychol Med"},{"issue":"7","key":"pone.0331261.ref009","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1007\/s00787-017-1060-5","article-title":"Mental disorders and the risk for the subsequent first suicide attempt: results of a community study on adolescents and young adults","volume":"27","author":"M Mich\u00e9","year":"2018","journal-title":"Eur Child Adolesc Psychiatry"},{"key":"pone.0331261.ref010","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s12904-016-0088-5","article-title":"Physical compared to mental diseases as reasons for committing suicide: a retrospective study","volume":"15","author":"M Fegg","year":"2016","journal-title":"BMC Palliat Care"},{"issue":"1","key":"pone.0331261.ref011","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/jcpp.12878","article-title":"What distinguishes adolescents with suicidal thoughts from those who have attempted suicide? 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