{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T06:35:40Z","timestamp":1790922940426,"version":"4.1.0"},"reference-count":74,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:00:00Z","timestamp":1758758400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00c3\u00b6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","award":["IICT_33IC30_173552"],"award-info":[{"award-number":["IICT_33IC30_173552"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Swiss Tobacco Prevention Fund","award":["19.017477"],"award-info":[{"award-number":["19.017477"]}]},{"DOI":"10.13039\/501100013362","name":"Swiss Cancer Research","doi-asserted-by":"crossref","award":["KFS4744-02-2019"],"award-info":[{"award-number":["KFS4744-02-2019"]}],"id":[{"id":"10.13039\/501100013362","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Introduction<\/jats:title>\n<jats:p>Tobacco smoking is associated with adverse health outcomes for both pregnant women and their offspring. Smoking cessation counseling is an effective method to help women quit smoking. Developing a targeted smoking cessation intervention could benefit those who struggle to quit tobacco and potentially reduce the harm due to any co-occurring tobacco use. Assessing the prevalence of tobacco, electronic nicotine delivery systems (ENDS), nicotine replacement therapy (NRT), and cannabinoid use in pregnancy is key to developing such interventions. Thus, we aimed to assess the prevalence and patterns of tobacco, ENDS, NRT, and cannabinoid use in pregnancy. We further aimed to assess the prevalence of smoking cessation counseling intervention.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Materials and methods<\/jats:title>\n<jats:p>We conducted a cross-sectional survey among pregnant women attending regular clinical visits at Spitalzentrum Biel between February and May 2023 (n\u2009=\u2009262). Frequency and proportion along with 95% confidence intervals (CI) were reported for tobacco, ENDS, NRT, and cannabinoid use in pregnancy.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Tobacco use was reported among 7.6% (20\/262, 95% CI: 4.2%\u221211.1%) of the included pregnant women. Tobacco cigarettes (conventional or roll-on) were used by 7.3% (19\/262, 95% CI: 3.8%\u221210.7%) of the surveyed pregnant women, with 0.8% (2\/262, 95% CI: 0.0%\u22123.4%) of them reporting use of cigarettes along with ENDS and 0.4% (1\/262, 95% CI: 0.0%\u22123.8%) reporting use of the cigarettes with NRT. Cannabinoid use was reported by 3.8% (10\/262, 95% CI: 1.1%\u22127.0%) of pregnant women\u00a0and all of them used products with Cannabidiol (CBD) only. Additionally, only 25% (5\/20, 95% CI: 10.0%\u221248.3%) of tobacco users had received smoking cessation counseling intervention.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>The estimated prevalence of tobacco, ENDS, NRT, and cannabinoid use among the pregnant women in this survey was 7.6%, 0.8%, 0.4%, and 3.8% respectively. However, among tobacco users, only one-fourth received smoking cessation counseling intervention.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0332961","type":"journal-article","created":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T17:24:09Z","timestamp":1758821049000},"page":"e0332961","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Tobacco, electronic nicotine delivery system, nicotine replacement therapy, and cannabinoid use during pregnancy: A descriptive cross-sectional survey"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-0087-9657","authenticated-orcid":true,"given":"Sreemanjari","family":"Kandhasamy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phanie","family":"Baggio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Mathis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yolanda","family":"Mattmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emeline","family":"Maisonneuve","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reto","family":"Auer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Panchaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8276-7082","authenticated-orcid":true,"given":"Stephen P.","family":"Jenkinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2421-5925","authenticated-orcid":true,"given":"Anna","family":"Schoeni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,9,25]]},"reference":[{"issue":"6","key":"pone.0332961.ref001","first-page":"545","article-title":"Health effects of tobacco use and exposure","volume":"56","author":"M Bartal","year":"2001","journal-title":"Monaldi Arch Chest Dis"},{"issue":"1","key":"pone.0332961.ref002","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/GRF.0000000000000413","article-title":"Tobacco Use During Pregnancy","volume":"62","author":"T Crume","year":"2019","journal-title":"Clin Obstet Gynecol"},{"issue":"7","key":"pone.0332961.ref003","doi-asserted-by":"crossref","DOI":"10.1016\/S2214-109X(18)30223-7","article-title":"National, regional, and global prevalence of smoking during pregnancy in the general population: a systematic review and meta-analysis","volume":"6","author":"S Lange","year":"2018","journal-title":"Lancet Glob Health"},{"issue":"17","key":"pone.0332961.ref004","doi-asserted-by":"crossref","first-page":"393","DOI":"10.15585\/mmwr.mm7317a2","article-title":"Cigarette Smoking Among Pregnant Women During the Perinatal Period: Prevalence and Health Care Provider Inquiries - Pregnancy Risk Assessment Monitoring System, United States, 2021","volume":"73","author":"L Kipling","year":"2024","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"pone.0332961.ref005","unstructured":"Australian Institute of Health and Welfare. National Core Maternity Indicators: Smoking during pregnancy [Internet]. Canberra: AIHW; 2024 [cited 2024 Oct 22]. Available from: https:\/\/www.aihw.gov.au\/reports\/mothers-babies\/national-core-maternity-indicators\/contents\/antenatal-period-indicators\/smoking-during-pregnancy"},{"issue":"8","key":"pone.0332961.ref006","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1003182","article-title":"Changes in parental smoking during pregnancy and risks of adverse birth outcomes and childhood overweight in Europe and North America: An individual participant data meta-analysis of 229,000 singleton births","volume":"17","author":"EM Philips","year":"2020","journal-title":"PLoS Med"},{"key":"pone.0332961.ref007","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1186\/s12889-015-1552-5","article-title":"Maternal smoking and the risk of still birth: systematic review and meta-analysis","volume":"15","author":"TC Marufu","year":"2015","journal-title":"BMC Public Health"},{"issue":"3","key":"pone.0332961.ref008","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/S0749-3797(98)00089-0","article-title":"Effects of smoking during pregnancy. 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Tobacco monitoring Switzerland] [Internet]. 2009 Nov.[Cited 2024 May 21]. Available from: http:\/\/www.stoptabac.ch\/fr\/images\/stories\/documents_stop_tabac\/tabagisme%20et%20grossesse%20ofsp.pdf"},{"key":"pone.0332961.ref050","unstructured":"Enqu\u00eate nationale p\u00e9rinatale 2016. Les naissances et les \u00e9tablissements, situation et \u00e9volution depuis 2010 | Direction de la recherche, des \u00e9tudes, de l\u2019\u00e9valuation et des statistiques [Internet]. [cited 2024 Oct 22]. 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Available from: https:\/\/www.santepubliquefrance.fr\/import\/enquete-nationale-perinatale.-rapport-2021.-les-naissances-le-suivi-a-deux-mois-et-les-etablissements"},{"key":"pone.0332961.ref053","doi-asserted-by":"crossref","first-page":"602873","DOI":"10.3389\/ijph.2021.602873","article-title":"Trends in Tobacco Smoking in Pregnant Women: Data From French National Perinatal Surveys","volume":"66","author":"V Demiguel","year":"2021","journal-title":"Int J Public Health"},{"issue":"1","key":"pone.0332961.ref054","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.wombi.2018.11.012","article-title":"Smoking during pregnancy, stigma and secrets: Visual methods exploration in the UK","volume":"33","author":"A Grant","year":"2020","journal-title":"Women Birth"},{"issue":"1","key":"pone.0332961.ref055","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/aogs.12532","article-title":"Accuracy of self-reported smoking cessation during pregnancy","volume":"94","author":"VT Tong","year":"2015","journal-title":"Acta Obstet Gynecol Scand"},{"key":"pone.0332961.ref056","doi-asserted-by":"crossref","first-page":"1139325","DOI":"10.3389\/fpsyt.2023.1139325","article-title":"Effects of cannabis regulation in Switzerland: Study protocol of a randomized controlled trial","volume":"14","author":"L Baltes-Flueckiger","year":"2023","journal-title":"Front Psychiatry"},{"issue":"8","key":"pone.0332961.ref057","doi-asserted-by":"crossref","first-page":"3397","DOI":"10.1038\/s41380-023-02130-y","article-title":"Fetal cannabidiol (CBD) exposure alters thermal pain sensitivity, problem-solving, and prefrontal cortex excitability","volume":"28","author":"KS Swenson","year":"2023","journal-title":"Mol Psychiatry"},{"issue":"1","key":"pone.0332961.ref058","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1038\/s41398-022-02271-8","article-title":"In utero exposure to cannabidiol disrupts select early-life behaviors in a sex-specific manner","volume":"12","author":"D Iezzi","year":"2022","journal-title":"Transl Psychiatry"},{"key":"pone.0332961.ref059","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.forsciint.2018.08.009","article-title":"Cannabinoid concentrations in blood and urine after smoking cannabidiol joints","volume":"291","author":"U Meier","year":"2018","journal-title":"Forensic Sci Int"},{"key":"pone.0332961.ref060","unstructured":"Bundesamt f\u00fcr Gesundheit BAG, Heilmittelinstitut S Schweizerisches, Bundesamt f\u00fcr Lebensmittelsicherheit und Veterin\u00e4rwesen BLV, Kantonsapothekervereinigung KAV. Produkte mit Cannabidiol (CBD) und anderen Cannabinoiden, die nicht dem Bet\u00e4ubungsmittelrecht unterliegen: \u00dcberblick und Vollzugshilfe [Internet]. 2024 Apr. [Cited 2024 Jul 23]. Available from: https:\/\/www.swissmedic.ch\/swissmedic\/de\/home\/news\/mitteilungen\/produkte-mit-cannabidiol--cbd----ueberblick.html"},{"key":"pone.0332961.ref061","unstructured":"Zobel F, Notari L, Schneider E, Rudmann O. Cannabidiol (CBD): analyse de situation [Internet]. 2018.[Cited 2024 Aug 2]. 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