{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T10:07:34Z","timestamp":1791540454142,"version":"4.3.4"},"reference-count":34,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T00:00:00Z","timestamp":1759708800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006483","name":"Abbvie","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Sandoz"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Objectives<\/jats:title>\n<jats:p>To evaluate if self-assessed rheumatic disease activity in patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA) or ankylosing spondyloarthritis (AS) is linked to local weather.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>In this prospective, multicentre study in Switzerland, adult patients were asked to report geographic location and rheumatic disease activity by means of Routine Assessment of Patient Index Data 3 (RAPID3)) via a webApp. The associations between RAPID3 scores and weather data on the day of the RAPID3 entry and the preceding week was investigated through regression analysis.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>238 patients were included (61.3% female). 100 patients had RA (baseline mean DAS28-CRP 2.8), 47 patients had PsA, and 91 patients had AS (mean BASDAI 3.8). 45.0% of all patients declared themselves as meteorosensitive. In the entire cohort, we found a weak negative correlation (r\u2009=\u2009\u22120.167) between RAPID3 and air pressure, the correlations between the remaining weather variables were weak (r\u2009&lt;\u20090.1). In the subgroups of meteorosensitive AS and PsA patients, we identified negative correlations between RAPID3 and air pressure (r\u2009=\u2009\u22120.321 and \u22120.232 respectively). In the AS meteorosensitive group, there was also weak correlation between wind and RAPID3 (r\u2009=\u20090.144). In RA patients, only negligible correlations (r\u2009&lt;\u20090.1) were observed, regardless of meteorosensitivity. In all analyses, also in the analyses of weather changes over the preceding week, we failed to identify effect sizes that exceed the minimal clinically important difference of the RAPID3.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>We did not find weather to be a major factor in disease activity of RA, AS and PsA patients receiving DMARD treatment.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0333022","type":"journal-article","created":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T17:26:22Z","timestamp":1759771582000},"page":"e0333022","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Meteorosensitivity of patients with rheumatic musculoskeletal diseases"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9183-550X","authenticated-orcid":true,"given":"Ulrich A.","family":"Walker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3095-8231","authenticated-orcid":true,"given":"Katja","family":"Nettermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-0019-8411","authenticated-orcid":true,"given":"Sebastian","family":"Walker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9921-2369","authenticated-orcid":true,"given":"Adam","family":"Streeter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronika 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Bruce","year":"2005","journal-title":"Clin Exp Rheumatol"},{"key":"pone.0333022.ref004","first-page":"1745","article-title":"Clinical utility and validity of self assessed joint involvement in rheumatoid arthritis (RA) patients with low active disease","volume":"62","author":"H Radner","year":"2010","journal-title":"Arthritis Rheum"},{"issue":"3","key":"pone.0333022.ref005","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1097\/BOR.0b013e328345743a","article-title":"Monitoring rheumatoid arthritis","volume":"23","author":"JS Smolen","year":"2011","journal-title":"Curr Opin Rheumatol"},{"issue":"4","key":"pone.0333022.ref006","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.rdc.2009.10.017","article-title":"A multi-dimensional health assessment questionnaire (MDHAQ) and routine assessment of patient index data (RAPID3) scores are informative in patients with all rheumatic diseases","volume":"35","author":"T Pincus","year":"2009","journal-title":"Rheum Dis Clin 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Disease Activity Index (BASDAI) Scores Yield Similar Information in 85 Korean Patients With Ankylosing Spondylitis Seen in Usual Clinical Care","volume":"21","author":"S-H Park","year":"2015","journal-title":"J Clin Rheumatol"},{"issue":"4","key":"pone.0333022.ref010","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0123582","article-title":"A comparison of disease burden in rheumatoid arthritis, psoriatic arthritis and axial spondyloarthritis","volume":"10","author":"B Michelsen","year":"2015","journal-title":"PLoS One"},{"issue":"10","key":"pone.0333022.ref011","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1093\/rheumatology\/kex229","article-title":"Disease activity dynamics in rheumatoid arthritis: patients\u2019 self-assessment of disease activity via WebApp","volume":"56","author":"UA Walker","year":"2017","journal-title":"Rheumatology 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