{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T15:20:29Z","timestamp":1791645629654,"version":"4.3.4"},"reference-count":30,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T00:00:00Z","timestamp":1759708800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Xiangya Joint Fund for Early-Career Nursing Faculty from Xiangya School of Nursing, Central South University","award":["2024XYHLQNLHJJ01"],"award-info":[{"award-number":["2024XYHLQNLHJJ01"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Peripherally inserted central venous catheters (PICC) associated bloodstream infections is a type of central line-associated bloodstream infection (CLABSI), the purpose of this scoping review was to analyse and summarize the risk prediction models for PICC-CLABSI to provide insights for clinical nursing practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A scoping review was conducted from six bibliographic databases including CNKI, Wanfang Database, VIP Chinese Journal Database, PubMed, Embase, and Web of Science, from inception to November 5, 2024. Screening was performed and relevant data was extracted independently by two researchers, the risk of bias was assessed using the Prediction model Risk Of Bias Assessment Tool (PROBAST).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eight studies met the inclusion criteria, which included two score models, six nomograms, and one ELM model. The included studies exhibited a high risk of bias, mainly due to methodological heterogeneity. Four models underwent external validation, two were assessed for goodness of fit. The most frequently identified predictors including catheter indwelling time, maintenance cycle\/frequency, multilumen catheters, PICC parenteral nutrition, diabetes, and malignant tumors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The risk prediction models for PICC-CLABSI demonstrated strong predictive performance. Future research should carefully address all elements of PROBAST framework during study design phase. This will facilitate both internal and external validation, as well as differentiation, calibration, and evaluation of clinical practicality. The ultimate objective is to develop a PICC-CLABSI risk prediction model that exhibits low bias risk, robust predictive performance, and high clinical applicability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0333466","type":"journal-article","created":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T17:23:49Z","timestamp":1759771429000},"page":"e0333466","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Models for predicting the risk of bloodstream infections associated with peripherally inserted central venous catheters: A scoping review"],"prefix":"10.1371","volume":"20","author":[{"given":"Langping","family":"Cao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingxiang","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiqiang","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shihua","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxuan","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sailin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoran","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0548-5417","authenticated-orcid":true,"given":"Yanhui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,10,6]]},"reference":[{"key":"pone.0333466.ref001","article-title":"Central line\u2013associated blood stream infections","volume-title":"StatPearls","author":"Y Haddadin","year":"2024"},{"issue":"1","key":"pone.0333466.ref002","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1136\/bmjqs-2021-013015","article-title":"Improving peripherally inserted central catheter appropriateness and reducing device-related complications: a quasiexperimental study in 52 Michigan hospitals","volume":"31","author":"V Chopra","year":"2022","journal-title":"BMJ Qual Saf"},{"issue":"1","key":"pone.0333466.ref003","doi-asserted-by":"crossref","first-page":"15074","DOI":"10.1038\/s41598-017-10037-2","article-title":"The microbiological characteristics and risk factors for PICC-related bloodstream infections in intensive care unit","volume":"7","author":"S Zhang","year":"2017","journal-title":"Sci Rep"},{"issue":"10","key":"pone.0333466.ref004","first-page":"1413","article-title":"Pathogen analysis and predictive model design of catheter-related bloodstream infection in patients undergoing PICC catheterization for intravenous therapy","volume":"20","author":"Y Jiang","year":"2022","journal-title":"Chinese General Nursing"},{"issue":"1","key":"pone.0333466.ref005","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000018494","article-title":"Early mortality attributable to PICC-lines in 4 public hospitals of Marseille from 2010 to 2016 (Revised V3)","volume":"99","author":"S Bessis","year":"2020","journal-title":"Medicine (Baltimore)"},{"issue":"7","key":"pone.0333466.ref006","doi-asserted-by":"crossref","first-page":"989","DOI":"10.2169\/internalmedicine.8184-21","article-title":"Risk Factors for Complications Associated with Peripherally Inserted Central Catheters During Induction Chemotherapy for Acute Myeloid Leukemia","volume":"61","author":"T Ban","year":"2022","journal-title":"Intern Med"},{"issue":"1","key":"pone.0333466.ref007","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1186\/s40001-021-00546-2","article-title":"Analysis of risk factors of PICC-related bloodstream infection in newborns: implications for nursing care","volume":"26","author":"Y Hu","year":"2021","journal-title":"Eur J Med Res"},{"key":"pone.0333466.ref008","unstructured":"National Health Commission of the People's Republic of China. 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