{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:56:18Z","timestamp":1783040178261,"version":"3.54.6"},"reference-count":44,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T00:00:00Z","timestamp":1759795200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007316","name":"Division of Cancer Prevention, National Cancer Institute","doi-asserted-by":"publisher","award":["#U54CA180905"],"award-info":[{"award-number":["#U54CA180905"]}],"id":[{"id":"10.13039\/100007316","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010628","name":"Center for Tobacco Products","doi-asserted-by":"publisher","award":["#U54CA180905"],"award-info":[{"award-number":["#U54CA180905"]}],"id":[{"id":"10.13039\/100010628","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>Adolescent e-cigarette and cannabis vaping have become significant public health concerns, with rates increasing in recent years. However, there is limited research on the impacts of COVID-related stress on adolescent vaping. This study examined the longitudinal impacts of COVID-related stress on adolescent e-cigarette and cannabis vaping, including the mediating role of vaping susceptibility (which measures a lack of a firm commitment not to use a substance). We examined the prospective associations of COVID-related stress during remote learning (2020\u20132021) with e-cigarette and cannabis vaping use two years later (2022\u20132023) through the mediation of vaping susceptibility (2021\u20132022) among a cohort of students recruited as ninth graders from nine public high schools across Los Angeles County and surveyed annually (N\u2009=\u20091,316). Higher levels of COVID-related stress were prospectively associated with increased susceptibility to vaping e-cigarettes (B\u2009=\u20090.04, p\u2009=\u2009.02) and cannabis (B\u2009=\u20090.04, p\u2009=\u2009.02) one year later, which in turn increased the odds of e-cigarette (B\u2009=\u20090.98, p\u2009=\u2009.003) and cannabis (B\u2009=\u20091.62, p\u2009&lt;\u2009.001) vaping two years later. This study highlights the critical need for effective, school-based prevention programs to reduce susceptibility to vaping, particularly during periods of heightened stress or future crises.<\/jats:p>","DOI":"10.1371\/journal.pone.0334159","type":"journal-article","created":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T17:32:43Z","timestamp":1759858363000},"page":"e0334159","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Prospective associations of COVID-related stress with vaping nicotine and cannabis among high school students: Mediated by vaping susceptibility"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6982-5807","authenticated-orcid":true,"given":"Ryan","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6617-1625","authenticated-orcid":true,"given":"Junhan","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dayoung","family":"Bae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larisa","family":"Albers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirin Emma","family":"Herzig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla Michelle","family":"Ramirez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Carvajal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Soto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9064-6603","authenticated-orcid":true,"given":"Jennifer B.","family":"Unger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,10,7]]},"reference":[{"key":"pone.0334159.ref001","volume-title":"Monitoring the Future national survey results on drug use, 1975\u20132023: Overview and detailed results for secondary school students. 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