{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:21:18Z","timestamp":1791814878572,"version":"4.3.4"},"reference-count":49,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:00:00Z","timestamp":1775088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>\n                    Hepatitis B virus (HBV) infection remains major public health concern in Ghana, where prevalence is high despite the availability of an effective vaccine. Informal sector workers represent a large proportion of the national workforce but have limited access to preventive health services. This study assessed hepatitis B vaccination coverage and its predictors among informal sector workers in Kejetia market, Kumasi, Ghana. A cross-sectional analytical study was conducted among 809 market workers selected using stratified random sampling across different occupational groups. Data were collected using structured interviewer-administered questionnaires covering sociodemographic characteristics, HBV awareness and knowledge, and vaccination history. Vaccination uptake was categorized as at least one dose (\u22651) and full coverage (\u22653 doses). Logistic regression analyses were used to identify predictors of vaccination uptake. Overall, only 137 (16.9%) had completed the three-dose schedule, though 256 (31.6%) of participants reported having received at least one dose of HBV vaccine. While 718 (88.8%) of respondents had heard of HBV infection, 619 (76.5%) reported very little or no knowledge about the disease, and 402 (49.7%) did not know its routes of transmission. Vaccination uptake was significantly higher among those who had received HBV-related health education, 175 (62.7%) compared to those who had not 18 (15.3%, p\u2009&lt;\u20090.001). In the multivariate logistic regression model,\u2009\u2264\u200930 years (aOR = 2.209, 95% CI [1.140\u20134.282],\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.019), secondary education (aOR = 2.426, 95% CI [1.220\u20134.824],\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.012), and tertiary education (aOR = 4.796, 95% CI [2.121\u201310.845],\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001) were the independent predictors of vaccination status. HBV vaccination coverage among informal sector workers in Kejetia Market is alarmingly low despite high general awareness of the infection. Sociodemographic factors and receipt of HBV-related health education strongly influenced uptake. These findings underscore the urgent need for targeted health education and subsidized vaccination programs tailored to informal sector workers in Ghana to achieve national HBV elimination goals.\n                  <\/jats:p>","DOI":"10.1371\/journal.pone.0334205","type":"journal-article","created":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T17:39:37Z","timestamp":1775151577000},"page":"e0334205","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Towards hepatitis B elimination in Ghana: vaccination coverage and its predictors among informal sector workers in Kejetia, Kumasi, Ghana"],"prefix":"10.1371","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0265-1822","authenticated-orcid":true,"given":"Michael Agyemang","family":"Obeng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel Kobina","family":"Okwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0898-6548","authenticated-orcid":true,"given":"Clinton Owusu","family":"Boateng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7531-4213","authenticated-orcid":true,"given":"Godfred Yawson","family":"Scott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua Kofi","family":"Attah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Senam Yawa Nunamey","family":"Ahadzie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathaniel Darko","family":"Antwi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6657-6721","authenticated-orcid":true,"given":"Pius","family":"Takyi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6891-2116","authenticated-orcid":true,"given":"De-Graft Kwaku Ofosu","family":"Boateng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6271-352X","authenticated-orcid":true,"given":"Augustine","family":"Yeboah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derrick","family":"Wedam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuella Asaamah","family":"Ofori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richwonder Abla","family":"Ahiable","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebenezer Oppong","family":"Gyamfi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5698-4461","authenticated-orcid":true,"given":"Akwasi Amponsah","family":"Abrampah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abu Abudu","family":"Rahamani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,4,2]]},"reference":[{"key":"pone.0334205.ref001","doi-asserted-by":"crossref","DOI":"10.1016\/S2468-1253(19)30349-8","article-title":"The global, regional, and national burden of cirrhosis by 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protection scheme among informal sector workers in Kumasi Metropolis of Ghana","volume":"12","author":"D Adei","year":"2019","journal-title":"BMC Res Notes"},{"key":"pone.0334205.ref015","article-title":"The Ghana National Health Insurance Scheme: Barriers to Access for Informal Workers","author":"L Alfers","year":"2023","journal-title":"WIEGO"},{"issue":"1","key":"pone.0334205.ref016","doi-asserted-by":"crossref","DOI":"10.1080\/2331205X.2021.1911441","article-title":"Improving upon the working environment of informal sector workers in Ghana: The role of planning","volume":"8","author":"D Adei","year":"2021","journal-title":"Cogent Medicine"},{"issue":"1","key":"pone.0334205.ref017","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s12914-018-0159-1","article-title":"Informal workers\u2019 access to health care services: findings from a qualitative study in the Kassena-Nankana districts of Northern Ghana","volume":"18","author":"J 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Chingle","year":"2017","journal-title":"Ann Afr Med"},{"issue":"4","key":"pone.0334205.ref046","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1007\/s10900-014-9975-y","article-title":"HBV Outreach Programs Significantly Increase Knowledge and Vaccination Rates Among Asian Pacific Islanders","volume":"40","author":"T Zacharias","year":"2015","journal-title":"J Community Health"},{"issue":"4","key":"pone.0334205.ref047","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0231930","article-title":"Knowledge, risk of infection, and vaccination status of hepatitis B virus among rural high school students in Nanumba North and South Districts of Ghana","volume":"15","author":"A Adam","year":"2020","journal-title":"PLoS One"},{"issue":"1","key":"pone.0334205.ref048","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0306961","article-title":"Knowledge and occupational practices of beauticians and barbers in the transmission of viral hepatitis: A mixed-methods study in Volta Region of Ghana","volume":"20","author":"S Adjei-Gyamfi","year":"2025","journal-title":"PLoS One"},{"issue":"6","key":"pone.0334205.ref049","doi-asserted-by":"crossref","DOI":"10.1111\/hsc.13860","article-title":"Correlates of hepatitis B testing in Ghana: The role of knowledge, stigma endorsement and knowing someone with hepatitis B","volume":"30","author":"CA Adjei","year":"2022","journal-title":"Health Soc Care Community"}],"container-title":["PLOS One"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0334205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T17:39:46Z","timestamp":1775151586000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0334205"}},"subtitle":[],"editor":[{"given":"Jason 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