{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T18:27:30Z","timestamp":1762280850334,"version":"build-2065373602"},"reference-count":25,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T00:00:00Z","timestamp":1762214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00c3\u00a7\u00c3\u00a3o de Aperfei\u00c3\u00a7oamento de Pessoal de N\u00c3vel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Engevet","award":["NA"],"award-info":[{"award-number":["NA"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>The present study aims to describe and evaluate the effectiveness and potential applicability of a new implant designed to transpose the tibial tuberosity. The implant consists of a customized plate for fixation on the tibia, containing a hole for the insertion of a transposition screw in the tibial tuberosity. Computed tomography was performed on 21 cadaveric canine tibias to plan the surgical technique and calculate the desired transposition. Subsequently, an osteotomy of the tibial tuberosity was performed, extending 60% of the lateral cortex and 80% of the medial cortex to maintain a bone bridge between the tibial shaft and the osteotomized segment. After the osteotomy, the implant was fixed to the tibia, and the tibial tuberosity was transposed slowly and gradually using the transposition screw. The samples underwent radiographic evaluation and manual palpation following the application to detect tibial crest fractures. The plate\u2019s shape adequately fit the medial surface of the tibia, and the implant was effective in promoting a slow and gradual transposition in canine cadavers without the need for an additional surgical device to perform the maneuver. The implant proved to be effective in achieving the desired transposition in a progressive, gradual, and slow manner.<\/jats:p>","DOI":"10.1371\/journal.pone.0335274","type":"journal-article","created":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T18:22:37Z","timestamp":1762280557000},"page":"e0335274","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of a new implant for Tibial Tuberosity Transposition in dogs: An ex vivo study"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-8282-114X","authenticated-orcid":true,"given":"Gabriel","family":"Rampanelli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olicies","family":"da Cunha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anderson Luiz","family":"de Carvalho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9805-989X","authenticated-orcid":true,"given":"C\u00e1ssio Ricardo Auada","family":"Ferrigno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila Aparecida","family":"Luiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura Ayala","family":"Lazarotto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas Dill","family":"Mocellin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5122-5563","authenticated-orcid":true,"given":"Jo\u00e3o Pedro Cosmo","family":"Machado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Lunardelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2025,11,4]]},"reference":[{"issue":"1","key":"pone.0335274.ref001","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1748-5827.2006.00004.x","article-title":"Patellar luxation in 70 large breed dogs","volume":"47","author":"SE Gibbons","year":"2006","journal-title":"J Small Anim Pract"},{"issue":"5","key":"pone.0335274.ref002","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/jsap.13311","article-title":"Canine medial patellar luxation","volume":"62","author":"KL Perry","year":"2021","journal-title":"J Small Anim Pract"},{"issue":"3","key":"pone.0335274.ref003","article-title":"Preoperative and postoperative stance analysis in dogs with patellar luxation confirms lameness improvement after surgery","volume":"84","author":"LC DiGiovanni","year":"2023","journal-title":"Am J Vet Res"},{"key":"pone.0335274.ref004","first-page":"23","article-title":"Patellar luxation in dogs","volume":"9","author":"F Di Dona","year":"2018","journal-title":"Vet Med (Auckl)"},{"issue":"5","key":"pone.0335274.ref005","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1111\/vsu.13661","article-title":"Proximodistal and caudocranial position of the insertion of the patellar ligament on the tibial tuberosity and patellar ligament length of normal stifles and stifles with grade II medial patellar luxation in small-breed dogs","volume":"50","author":"L Feldmane","year":"2021","journal-title":"Vet Surg"},{"issue":"3","key":"pone.0335274.ref006","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1532-950x.2005.00040.x","article-title":"Pre- and postoperative radiographic and computed tomographic evaluation of dogs with medial patellar luxation","volume":"34","author":"HA Towle","year":"2005","journal-title":"Vet Surg"},{"issue":"4","key":"pone.0335274.ref007","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/jsap.13093","article-title":"The natural history of canine occult Grade II medial patellar luxation: an observational study","volume":"61","author":"L Hamilton","year":"2020","journal-title":"J Small Anim Pract"},{"issue":"5","key":"pone.0335274.ref008","doi-asserted-by":"crossref","first-page":"364","DOI":"10.3415\/VCOT-16-05-0073","article-title":"Prevalence, treatment and outcome of patellar luxation in dogs in Italy. 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