{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T14:39:06Z","timestamp":1780583946312,"version":"3.54.1"},"reference-count":16,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the efficacy of the smart eye camera (SEC), a portable smartphone-attachable camera, in assessing eyes following lamellar corneal transplantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This retrospective study included consecutive patients who underwent lamellar corneal transplantation between December 1\n                      <jats:sup>st<\/jats:sup>\n                      2023 and August 31\n                      <jats:sup>st<\/jats:sup>\n                      2024. Postoperative evaluations were performed using the SEC and a slit-lamp microscope. All images from the two devices were evaluated by two corneal specialists in a blinded fashion to determine the amount of air or gas in the anterior chamber, and the presence of pupillary block and graft detachment. Sensitivity, specificity, and interrater agreement were calculated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 26 eyes from 23 patients (12 males and 11 females, mean age: 68.7\u2009\u00b1\u200915.2 years) were included in this study. Indications for lamellar keratoplasty included endothelial dysfunction (11 eyes were treated with Descemet membrane endothelial keratoplasty and 9 with Descemet stripping automated endothelial keratoplasty), as well as corneal opacity (3 eyes were treated with deep anterior lamellar keratoplasty). Regarding the amount of air or gas in the anterior chamber, the two raters had consistent judgments using the SEC (intraclass correlation coefficient\u2009=\u20090.817 [95% confidence interval: 0.616, 0.918]). A difference in pupillary block identification was found between the two examiners using the SEC, with a Kappa coefficient of 0.646. Neither examiner was able to identify the presence of graft detachment using the SEC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The smartphone-attachable SEC was useful in the evaluation of air\/gas volume and pupillary block but not for detecting graft detachment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0335450","type":"journal-article","created":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T18:27:21Z","timestamp":1762367241000},"page":"e0335450","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of post-keratoplasty status with a portable and smartphone-attachable smart eye camera"],"prefix":"10.1371","volume":"20","author":[{"given":"Yuto","family":"Yukari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Senoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8704-680X","authenticated-orcid":true,"given":"Takahiko","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4578-0384","authenticated-orcid":true,"given":"Toshiki","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Hara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Nishimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shintaro","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eisuke","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoru","family":"Yamagami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,11,5]]},"reference":[{"key":"pone.0335450.ref001","doi-asserted-by":"crossref","first-page":"100768","DOI":"10.1016\/j.preteyeres.2019.07.001","article-title":"Immune reactions after modern lamellar (DALK, DSAEK, DMEK) versus conventional penetrating corneal transplantation","volume":"73","author":"D Hos","year":"2019","journal-title":"Prog Retin Eye Res"},{"issue":"3","key":"pone.0335450.ref002","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.ajo.2007.05.015","article-title":"Endothelial cell density after posterior lamellar keratoplasty: five- to seven-year follow-up","volume":"144","author":"BTH van Dooren","year":"2007","journal-title":"Am J Ophthalmol"},{"issue":"3","key":"pone.0335450.ref003","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1136\/bjo.81.3.184","article-title":"Deep lamellar keratoplasty with complete removal of pathological stroma for vision improvement","volume":"81","author":"J Sugita","year":"1997","journal-title":"Br J Ophthalmol"},{"issue":"4","key":"pone.0335450.ref004","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1097\/00003226-200205000-00009","article-title":"Deep lamellar keratoplasty: surgical techniques for anterior lamellar keratoplasty with and without baring of Descemet\u2019s membrane","volume":"21","author":"M Anwar","year":"2002","journal-title":"Cornea"},{"issue":"12","key":"pone.0335450.ref005","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1097\/ICO.0b013e31820d86bd","article-title":"Optical coherence tomography, Scheimpflug imaging, and slit-lamp biomicroscopy in the early detection of graft detachment after Descemet membrane endothelial keratoplasty","volume":"30","author":"K Moutsouris","year":"2011","journal-title":"Cornea"},{"issue":"12","key":"pone.0335450.ref006","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1007\/s00417-016-3484-x","article-title":"Detection of graft detachments immediately following Descemet membrane endothelial keratoplasty (DMEK) comparing time domain and spectral domain OCT","volume":"254","author":"S Siebelmann","year":"2016","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"3","key":"pone.0335450.ref007","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.jcjo.2021.04.012","article-title":"Postoperative supine position after primary Descemet-stripping automated endothelial keratoplasty reduces graft detachment rate","volume":"57","author":"M Safir","year":"2022","journal-title":"Can J Ophthalmol"},{"issue":"1","key":"pone.0335450.ref008","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/j.1755-3768.2012.02560.x","article-title":"The role of postoperative positioning after DSAEK in preventing graft dislocation","volume":"92","author":"M Saethre","year":"2014","journal-title":"Acta Ophthalmol"},{"issue":"1","key":"pone.0335450.ref009","doi-asserted-by":"crossref","first-page":"3099","DOI":"10.1038\/s41598-025-87820-z","article-title":"Clinical evaluation of corneal ulcer with a portable and smartphone-attachable slit lamp device: Smart Eye Camera","volume":"15","author":"S Ghafarian","year":"2025","journal-title":"Sci Rep"},{"issue":"8","key":"pone.0335450.ref010","doi-asserted-by":"crossref","first-page":"576","DOI":"10.3390\/diagnostics10080576","article-title":"Evaluation of Nuclear Cataract with Smartphone-Attachable Slit-Lamp Device","volume":"10","author":"H Yazu","year":"2020","journal-title":"Diagnostics (Basel)"},{"issue":"3","key":"pone.0335450.ref011","doi-asserted-by":"crossref","first-page":"535","DOI":"10.3390\/diagnostics11030535","article-title":"Clinical Observation of Allergic Conjunctival Diseases with Portable and Recordable Slit-Lamp Device","volume":"11","author":"H Yazu","year":"2021","journal-title":"Diagnostics (Basel)"},{"issue":"4","key":"pone.0335450.ref012","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1080\/09286586.2019.1600199","article-title":"Repeatability and Reproducibility of Slit Lamp, Optical Coherence Tomography, and Scheimpflug Measurements of Corneal Scars","volume":"26","author":"M Das","year":"2019","journal-title":"Ophthalmic Epidemiol"},{"issue":"4","key":"pone.0335450.ref013","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.3390\/s21041436","article-title":"A Study Validating the Estimation of Anterior Chamber Depth and Iridocorneal Angle with Portable and Non-Portable Slit-Lamp Microscopy","volume":"21","author":"E Shimizu","year":"2021","journal-title":"Sensors (Basel)"},{"key":"pone.0335450.ref014","author":"R Core Team."},{"issue":"6","key":"pone.0335450.ref015","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.ajo.2009.06.034","article-title":"Visually significant and nonsignificant complications arising from Descemet stripping automated endothelial keratoplasty","volume":"148","author":"CY Shih","year":"2009","journal-title":"Am J Ophthalmol"},{"issue":"8","key":"pone.0335450.ref016","doi-asserted-by":"crossref","first-page":"576","DOI":"10.3390\/diagnostics10080576","article-title":"Evaluation of Nuclear Cataract with Smartphone-Attachable Slit-Lamp Device","volume":"10","author":"H Yazu","year":"2020","journal-title":"Diagnostics (Basel)"}],"container-title":["PLOS One"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0335450","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T18:27:23Z","timestamp":1762367243000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0335450"}},"subtitle":[],"editor":[{"given":"Hidenaga","family":"Kobashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,11,5]]},"references-count":16,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2025,11,5]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0335450","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,5]]}}}