{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T22:21:29Z","timestamp":1775082089613,"version":"3.50.1"},"reference-count":29,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T00:00:00Z","timestamp":1764028800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008126","name":"Jeju National University Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008126","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the prognostic significance of venographic findings and procedural factors for long-term venous patency after thrombectomy in patients with May-Thurner syndrome (MTS)-associated deep vein thrombosis (DVT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study included 75 patients with iliofemoral DVT secondary to MTS, who underwent thrombectomy between January 2011 and April 2023. Key venographic findings\u2014venous stenosis (\u226550%), venous spur, and persistent collaterals\u2014along with stent placement and diameter were analyzed. The primary outcome was 24-month venous patency, assessed using univariate tests, Kaplan\u2013Meier survival analysis, and multivariate Cox proportional hazards modeling.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At 24 months, 58 patients (77.3%) maintained venous patency, whereas 17 (22.7%) experienced reocclusion. Univariate and Kaplan\u2013Meier analyses showed that stenosis \u226550%, venous spur, persistent collaterals, and absence of stent placement were significantly associated with reduced patency (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). However, in the multivariate Cox model, only venous stenosis \u226550% remained a statistically significant independent predictor of reocclusion (hazard ratio [HR]=5.04; 95% Confidence Interval: 1.28\u201319.82;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.021). Stent placement (HR\u2009=\u20091.78;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.337) and diameter (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.349) were not independently associated with patency.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Residual venous stenosis \u226550% following thrombectomy is an independent predictor of reduced long-term patency in patients with MTS. While stent placement was associated with better outcomes in the univariate analysis, it did not independently predict patency after adjustment, likely due to treatment-related confounding factors. Effective anatomical resolution of stenosis may be more critical than stent deployment. Prospective studies are warranted to clarify the prognostic impact of venographic findings and interventional strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0336037","type":"journal-article","created":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T18:32:57Z","timestamp":1764095577000},"page":"e0336037","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prognostic factors influencing venous patency after thrombectomy in patients with May-Thurner syndrome"],"prefix":"10.1371","volume":"20","author":[{"given":"Chang Hoon","family":"Oh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8406-6645","authenticated-orcid":true,"given":"In 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Nam","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung-Joon","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youngjong","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2025,11,25]]},"reference":[{"issue":"5","key":"pone.0336037.ref001","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1177\/000331975700800505","article-title":"The cause of the predominantly sinistral occurrence of thrombosis of the pelvic veins","volume":"8","author":"R May","year":"1957","journal-title":"Angiology"},{"issue":"5543","key":"pone.0336037.ref002","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1136\/bmj.2.5543.14","article-title":"Iliac vein compression.--Its relation to iliofemoral thrombosis and the post-thrombotic 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