{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T19:08:14Z","timestamp":1772132894074,"version":"3.50.1"},"reference-count":64,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Healthcare initiatives have a larger impact if effective initiatives are spread (brought from one site to the next) or scaled (infrastructure developed to underpin and support widespread implementation), while sustaining initial benefits. Unfortunately, many initiatives, including digital health initiatives, remain confined to the pilot stage. Of those initiatives that do progress, little is known about how to plan for the equitable spread and scale of effective initiatives. There are many structural \u201cmodels\u201d of spread and scale, defined here as conceptual representations of how initiatives are organised and delivered across multiple settings (i.e., hub-and-spoke model), yet little is known about these models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Primary Objective:<\/jats:italic>\n                      To identify and describe structural models for spreading and scaling digital health initiatives.\n                      <jats:italic>Secondary Objectives:<\/jats:italic>\n                      1. To describe the associated factors, strengths, limitations, and necessary preconditions associated with each model. 2. To describe the barriers and facilitators experienced when applying each model. 3. To explore whether and how each model prioritized equitable delivery of care. 4. To determine which pre-established types of scale (horizontal, vertical, diversification, and spontaneous) are associated with each model.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A scoping review will be conducted following Joanna Briggs Institute (JBI) methodology and reported in accordance with PRISMA-ScR guidelines. The search strategy includes peer-reviewed databases for health and business, alongside grey literature sources. Eligibility criteria follow the Population-Concept-Context framework, focusing on digital health initiatives delivered in healthcare settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The review will produce a comprehensive overview of structural models for spreading and scaling digital health initiatives, including model names, descriptions, strengths, limitations, preconditions, associated barriers and facilitators of applying each model, relationships between models and established types of scale, and equity considerations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec005\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This novel review aims to inform practical planning of how to bring digital health initiatives to new settings and populations, to support more equitable access to these initiatives.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0336730","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T18:28:39Z","timestamp":1772130519000},"page":"e0336730","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Structural models for spreading and scaling digital health initiatives: A scoping review 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