{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T01:00:37Z","timestamp":1783040437250,"version":"3.54.6"},"reference-count":60,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:00:00Z","timestamp":1764806400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The Oropouche virus (OROV), discovered in 1955, has evolved from being a pathogen limited to the Amazon basin to becoming a growing threat to public health in Latin America. Because its symptoms are similar to those of dengue and zika, diagnosis is complicated. In this context, the objective of this study is to determine the prevalence of epidemiological and clinical characteristics in Peruvian patients diagnosed with Oropouche.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic review and meta-analysis were performed in accordance with PRISMA guidelines. An exhaustive literature search was conducted up to April 10, 2025, across ten databases using MeSH terms like \u201cOropouche\u201d and \u201cPeru,\u201d combined with Boolean operators. Only observational studies conducted in Peru that reported confirmed OROV infections through reverse transcription polymerase chain reaction (RT-PCR) or enzyme-linked immunosorbent assay (ELISA), and that described clinical or epidemiological characteristics, were included. The methodological quality of these studies was evaluated using the JBI-MAStARI tool. To estimate the pooled prevalence and 95% confidence intervals, random-effects models were applied in R (version 4.2.3). Heterogeneity was assessed using the I\u00b2 statistic, and publication bias was evaluated through funnel plots and Egger\u2019s test, when applicable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Six observational studies published between 2010 and 2020 were included, involving 396 Peruvian patients diagnosed with OROV by RT-PCR or ELISA. The studies were conducted in Piura, Loreto, Hu\u00e1nuco, Madre de Dios, and San Mart\u00edn. Most patients were between 20 and 30 years old; 44.9% were male. All studies were of moderate quality. Due to the limited number of studies, publication bias was not assessed. The most common symptoms were fever, headache, myalgia, arthralgia, and retro-ocular pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings of this study reveal a significant occurrence of diverse symptoms in Peruvian patients infected with OROV. Due to the clinical resemblance to other arboviruses, it is essential to establish more precise diagnostic methods to prevent misdiagnosis and underreporting. The existing evidence remains limited, highlighting the importance of enhancing epidemiological monitoring, improving diagnostic tools, and creating public health strategies specifically targeted at endemic regions to reduce the effects of this emerging infection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0337522","type":"journal-article","created":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T18:42:19Z","timestamp":1764873739000},"page":"e0337522","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Oropouche infection in Peruvian patients: A systematic review and meta-analysis"],"prefix":"10.1371","volume":"20","author":[{"given":"Darwin A.","family":"Le\u00f3n-Figueroa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin","family":"Aguirre-Milachay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milagros","family":"Diaz-Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Pierre","family":"Villanueva-De La Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin A.","family":"Garcia-Vasquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virgilio E.","family":"Failoc-Rojas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0839-2419","authenticated-orcid":true,"given":"Mario J.","family":"Valladares-Garrido","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,12,4]]},"reference":[{"issue":"10","key":"pone.0337522.ref001","doi-asserted-by":"crossref","first-page":"100904","DOI":"10.1016\/S2666-5247(24)00136-8","article-title":"Oropouche fever outbreak in Brazil: an emerging concern in Latin America","volume":"5","author":"R Sah","year":"2024","journal-title":"Lancet Microbe"},{"issue":"4","key":"pone.0337522.ref002","doi-asserted-by":"crossref","DOI":"10.1093\/jtm\/taae012","article-title":"Recreational substance use among international travellers","volume":"31","author":"S Charoensakulchai","year":"2024","journal-title":"J Travel Med"},{"issue":"26","key":"pone.0337522.ref003","doi-asserted-by":"crossref","first-page":"2400362","DOI":"10.2807\/1560-7917.ES.2024.29.26.2400362","article-title":"Oropouche fever cases diagnosed in Italy in two epidemiologically non-related travellers from Cuba, late May to early June 2024","volume":"29","author":"C Castilletti","year":"2024","journal-title":"Euro Surveill"},{"issue":"4","key":"pone.0337522.ref004","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0012962","article-title":"Clinical presentation of Oropouche virus infection: A systematic review and meta-analysis","volume":"19","author":"Z Wang","year":"2025","journal-title":"PLoS Negl Trop Dis"},{"issue":"9","key":"pone.0337522.ref005","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.3390\/v16091435","article-title":"Oropouche Virus (OROV) in Pregnancy: An Emerging Cause of Placental and Fetal Infection Associated with Stillbirth and Microcephaly following Vertical Transmission","volume":"16","author":"DA Schwartz","year":"2024","journal-title":"Viruses"},{"issue":"11","key":"pone.0337522.ref006","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.3201\/eid3011.241132","article-title":"Fatal Oropouche Virus Infections in Nonendemic Region, Brazil, 2024","volume":"30","author":"AC Bandeira","year":"2024","journal-title":"Emerg Infect Dis"},{"issue":"9","key":"pone.0337522.ref007","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.3390\/v16091498","article-title":"(Re-)Emergence of Oropouche Virus (OROV) Infections: Systematic Review and Meta-Analysis of Observational Studies","volume":"16","author":"M Ricc\u00f2","year":"2024","journal-title":"Viruses"},{"issue":"8","key":"pone.0337522.ref008","doi-asserted-by":"crossref","DOI":"10.1016\/S1473-3099(24)00418-3","article-title":"Preparedness for emerging epidemic threats: detection of Oropouche circulation in Cuba","volume":"24","author":"ME Toledo","year":"2024","journal-title":"Lancet Infect Dis"},{"key":"pone.0337522.ref009","doi-asserted-by":"crossref","first-page":"107487","DOI":"10.1016\/j.actatropica.2024.107487","article-title":"Integrated surveillance for Oropouche Virus: Molecular evidence of potential urban vectors during an outbreak in the Brazilian Amazon","volume":"261","author":"LHM Feitoza","year":"2025","journal-title":"Acta Trop"},{"key":"pone.0337522.ref010","article-title":"Key clinical manifestations to differentiate Oropouche fever from dengue and other arboviral diseases: a living systematic reviewRevis\u00e3o sistem\u00e1tica viva das manifesta\u00e7\u00f5es cl\u00ednicas da febre do Oropouche: caracter\u00edsticas-chave para diferenci\u00e1-la da dengue e de outras arboviroses","volume":"48","author":"F Tortosa","year":"2024","journal-title":"Rev Panam Salud Publica"},{"key":"pone.0337522.ref011","unstructured":"Sala de situaci\u00f3n. Cent Nac Epidemiol Prev Control Enfermedades n.d. [accessed September 30, 2025]. https:\/\/www.dge.gob.pe\/portalnuevo\/sala-de-situacion\/"},{"issue":"4","key":"pone.0337522.ref012","doi-asserted-by":"crossref","first-page":"86","DOI":"10.15585\/mmwr.mm7304a4","article-title":"Notes from the Field: Dengue Outbreak - Peru, 2023","volume":"73","author":"CV Munayco","year":"2024","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"4","key":"pone.0337522.ref013","first-page":"375","article-title":"Rapid spread of the emerging cosmopolitan genotype of dengue virus serotype 2, and expansion of dengue virus serotype 1 genotype V in Peru","volume":"41","author":"H Bailon","year":"2025","journal-title":"Rev Peru Med Exp Salud Publica"},{"key":"pone.0337522.ref014","article-title":"Circulation of DENV-2 serotype associated with increased risk of cumulative incidence of severe dengue and dengue with warning signs: A 16-year retrospective study in Peru","author":"JL Ca\u00f1ari-Casa\u00f1o","year":"2024","journal-title":"medRxiv"},{"key":"pone.0337522.ref015","doi-asserted-by":"crossref","first-page":"317","DOI":"10.3389\/fcimb.2017.00317","article-title":"Global Epidemiology of Dengue Outbreaks in 1990-2015: A Systematic Review and Meta-Analysis","volume":"7","author":"C Guo","year":"2017","journal-title":"Front Cell Infect Microbiol"},{"issue":"5","key":"pone.0337522.ref016","doi-asserted-by":"crossref","first-page":"769","DOI":"10.3390\/v16050769","article-title":"Retrospective Analysis of Severe Dengue by Dengue Virus Serotypes in a Population with Social Security, Mexico 2023","volume":"16","author":"PF Hern\u00e1ndez Bautista","year":"2024","journal-title":"Viruses"},{"issue":"3","key":"pone.0337522.ref017","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/S1473-3099(24)00566-8","article-title":"Serotype-specific epidemiological patterns of inapparent versus symptomatic primary dengue virus infections: a 17-year cohort study in Nicaragua","volume":"25","author":"S Bos","year":"2025","journal-title":"Lancet Infect Dis"},{"issue":"1","key":"pone.0337522.ref018","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3390\/v17010057","article-title":"Latin America\u2019s Dengue Outbreak Poses a Global Health Threat","volume":"17","author":"MT de Almeida","year":"2025","journal-title":"Viruses"},{"issue":"3","key":"pone.0337522.ref019","doi-asserted-by":"crossref","first-page":"439","DOI":"10.3390\/v17030439","article-title":"A Comprehensive Review of the Neglected and Emerging Oropouche Virus","volume":"17","author":"F Bai","year":"2025","journal-title":"Viruses"},{"issue":"11","key":"pone.0337522.ref020","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/j.ajic.2025.08.008","article-title":"Genomic and epidemiologic investigation of arboviral coinfections, Esp\u00edrito Santo, Brazil","volume":"53","author":"JZ Nodari","year":"2025","journal-title":"Am J Infect Control"},{"key":"pone.0337522.ref021","unstructured":"ARBO Portal - Oropouche - OPS\/OMS | Organizaci\u00f3n Panamericana de la Salud n.d. [accessed August 3, 2025]. https:\/\/www.paho.org\/es\/arbo-portal\/arbo-portal-oropouche"},{"issue":"7","key":"pone.0337522.ref022","doi-asserted-by":"crossref","DOI":"10.1016\/S1473-3099(23)00740-5","article-title":"Emergence of Oropouche fever in Latin America: a narrative review","volume":"24","author":"KM Wesselmann","year":"2024","journal-title":"Lancet Infect Dis"},{"issue":"1","key":"pone.0337522.ref023","doi-asserted-by":"crossref","first-page":"116882","DOI":"10.1016\/j.diagmicrobio.2025.116882","article-title":"Epidemiology, transmission dynamics, treatment strategies, and future perspectives on Oropouche virus","volume":"113","author":"BT Yoosuf","year":"2025","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"12","key":"pone.0337522.ref024","doi-asserted-by":"crossref","first-page":"3509","DOI":"10.1038\/s41591-024-03300-3","article-title":"Human outbreaks of a novel reassortant Oropouche virus in the Brazilian Amazon region","volume":"30","author":"FG Naveca","year":"2024","journal-title":"Nat Med"},{"issue":"4","key":"pone.0337522.ref025","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1111\/mve.12730","article-title":"Ecological niche modelling of Culicoides imicola and future range shifts under climate change scenarios in Italy","volume":"38","author":"I Del Lesto","year":"2024","journal-title":"Med Vet Entomol"},{"issue":"6","key":"pone.0337522.ref026","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1093\/jme\/tjad098","article-title":"Culicoides-borne Orbivirus epidemiology in a changing climate","volume":"60","author":"AR Hudson","year":"2023","journal-title":"J Med Entomol"},{"issue":"1","key":"pone.0337522.ref027","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40794-024-00236-x","article-title":"Addressing the emerging threat of Oropouche virus: implications and public health responses for healthcare systems","volume":"11","author":"OJ Okesanya","year":"2025","journal-title":"Trop Dis Travel Med Vaccines"},{"key":"pone.0337522.ref028","unstructured":"Orientaciones provisionales para la vigilancia entomol\u00f3gica y las medidas de prevenci\u00f3n de los vectores del virus de Oropouche - OPS\/OMS | Organizaci\u00f3n Panamericana de la Salud 2024. [accessed August 3, 2025]. https:\/\/www.paho.org\/es\/documentos\/orientaciones-provisionales-para-vigilancia-entomologica-medidas-prevencion-vectores"},{"key":"pone.0337522.ref029","doi-asserted-by":"crossref","first-page":"101596","DOI":"10.1016\/j.nmni.2025.101596","article-title":"The emergence of oropouche fever: A potential new threat?","volume":"65","author":"S Srivastava","year":"2025","journal-title":"New Microbes New Infect"},{"issue":"1","key":"pone.0337522.ref030","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/s41541-022-00456-2","article-title":"Baseline mapping of Oropouche virology, epidemiology, therapeutics, and vaccine research and development","volume":"7","author":"MA Files","year":"2022","journal-title":"NPJ Vaccines"},{"key":"pone.0337522.ref031","article-title":"PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews","volume":"372","author":"MJ Page","year":"2021","journal-title":"BMJ"},{"issue":"6","key":"pone.0337522.ref032","article-title":"Prevalence of dengue in febrile patients in Peru: A systematic review and meta-analysis","volume":"20","author":"DA Le\u00f3n-Figueroa","year":"2025","journal-title":"PLoS One"},{"issue":"6","key":"pone.0337522.ref033","article-title":"Epidemiological and clinical characteristics of Peruvian patients with mpox: A systematic review and meta-analysis","volume":"20","author":"DA Le\u00f3n-Figueroa","year":"2025","journal-title":"PLoS One"},{"issue":"7","key":"pone.0337522.ref034","article-title":"Oropouche virus infection in patients with acute febrile syndrome: Is a predictive model based solely on signs and symptoms useful?","volume":"17","author":"HV Durango-Chavez","year":"2022","journal-title":"PLoS One"},{"issue":"5","key":"pone.0337522.ref035","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.4269\/ajtmh.22-0259","article-title":"Etiologies of Acute Undifferentiated Febrile Illnesses in and near Iquitos from 1993 to 1999 in the Amazon River Basin of Peru","volume":"107","author":"DM Watts","year":"2022","journal-title":"Am J Trop Med Hyg"},{"issue":"1","key":"pone.0337522.ref036","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s13104-020-4937-1","article-title":"Oropouche infection a neglected arbovirus in patients with acute febrile illness from the Peruvian coast","volume":"13","author":"J Martins-Luna","year":"2020","journal-title":"BMC Res Notes"},{"key":"pone.0337522.ref037","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.ijid.2019.04.011","article-title":"First outbreak of Oropouche Fever reported in a non-endemic western region of the Peruvian Amazon: Molecular diagnosis and clinical characteristics","volume":"83","author":"W Silva-Caso","year":"2019","journal-title":"Int J Infect Dis"},{"issue":"11","key":"pone.0337522.ref038","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0187897","article-title":"Emerging and reemerging arboviruses: A new threat in Eastern Peru","volume":"12","author":"C Alva-Urcia","year":"2017","journal-title":"PLoS One"},{"key":"pone.0337522.ref039","first-page":"334","article-title":"Brote de Fiebre de Oropuche en Bagaz\u00e1n, San Mart\u00edn - Per\u00fa: Evaluaci\u00f3n Epidemiol\u00f3gica, Manifestaciones Gastrointestinales y Hemorr\u00e1gicas","author":"PP Alvarez-Falconi","year":"2010","journal-title":"Rev Gastroenterol Per\u00fa"},{"key":"pone.0337522.ref040","doi-asserted-by":"crossref","first-page":"199318","DOI":"10.1016\/j.virusres.2024.199318","article-title":"Oropouche virus: A neglected global arboviral threat","volume":"341","author":"Y Zhang","year":"2024","journal-title":"Virus Res"},{"issue":"5","key":"pone.0337522.ref041","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.4269\/ajtmh.16-0672","article-title":"Oropouche Virus: Clinical, Epidemiological, and Molecular Aspects of a Neglected Orthobunyavirus","volume":"96","author":"JF Travassos da Rosa","year":"2017","journal-title":"Am J Trop Med Hyg"},{"issue":"6","key":"pone.0337522.ref042","first-page":"67","article-title":"Clinical manifestations of Oropouche virus infection: A systematic review and meta-analysis","volume":"5","author":"M Giri","year":"2025","journal-title":"Med Int (Lond)"},{"key":"pone.0337522.ref043","unstructured":"Lima USM. Health Alert: Spread of Oropouche Virus in Peru - U.S. Embassy Lima, Peru (September 18, 2024). US Embassy Peru 2024. [accessed August 5, 2025]. https:\/\/pe.usembassy.gov\/health-alert-spread-of-oropouche-virus-in-peru-u-s-embassy-lima-peru-september-18-2024\/"},{"key":"pone.0337522.ref044","unstructured":"CDC. Clinical Overview of Oropouche Virus Disease. Oropouche 2025. [accessed August 5, 2025]. https:\/\/www.cdc.gov\/oropouche\/hcp\/clinical-overview\/index.html"},{"key":"pone.0337522.ref045","doi-asserted-by":"crossref","first-page":"102839","DOI":"10.1016\/j.tmaid.2025.102839","article-title":"Infectious diseases prevention and vaccination in migrants in Latin America: The challenges of transit through the treacherous Darien gap, Panama","volume":"65","author":"AJ Rodriguez-Morales","year":"2025","journal-title":"Travel Med Infect Dis"},{"key":"pone.0337522.ref046","article-title":"The impacts of climate change on the global range of Culicoides punctatus (Meigen, 1804) with notes on its status in Saudi Arabia","volume":"13","author":"ES Al-Malki","year":"2025","journal-title":"PeerJ"},{"issue":"4","key":"pone.0337522.ref047","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0013014","article-title":"Vector competence for Oropouche virus: A systematic review of pre-2024 experiments","volume":"19","author":"EN Gallichotte","year":"2025","journal-title":"PLoS Negl Trop Dis"},{"issue":"12","key":"pone.0337522.ref048","article-title":"Unprecedented Oropouche Fever Outbreak in Brazil: Could the M Segment-Encoded Proteins Provide Clues to Possible Insights?","volume":"96","author":"JVJ Silva J\u00fanior","year":"2024","journal-title":"J Med Virol"},{"issue":"2","key":"pone.0337522.ref049","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/S1473-3099(24)00619-4","article-title":"Re-emergence of Oropouche virus between 2023 and 2024 in Brazil: an observational epidemiological study","volume":"25","author":"GC Scachetti","year":"2025","journal-title":"Lancet Infect Dis"},{"issue":"2","key":"pone.0337522.ref050","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jcv.2008.11.006","article-title":"Oropouche fever epidemic in Northern Brazil: epidemiology and molecular characterization of isolates","volume":"44","author":"HB Vasconcelos","year":"2009","journal-title":"J Clin Virol"},{"issue":"6","key":"pone.0337522.ref051","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1590\/0074-02760150123","article-title":"Detection of Oropouche virus segment S in patients and inCulex quinquefasciatus in the state of Mato Grosso, Brazil","volume":"110","author":"BF Cardoso","year":"2015","journal-title":"Mem Inst Oswaldo Cruz"},{"issue":"2","key":"pone.0337522.ref052","doi-asserted-by":"crossref","first-page":"100177","DOI":"10.1016\/j.imj.2025.100177","article-title":"Mysterious Oropouche virus: Transmission, symptoms, and control","volume":"4","author":"S Porwal","year":"2025","journal-title":"Infect Med (Beijing)"},{"key":"pone.0337522.ref053","first-page":"100718","article-title":"The underdiagnosed threat of oropouche fever amidst dengue epidemics in Brazil","volume":"32","author":"PR Martins-Filho","year":"2024","journal-title":"Lancet Reg Health Am"},{"issue":"1","key":"pone.0337522.ref054","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1186\/s12985-025-02945-x","article-title":"Exploring the challenge of diagnosing and tracking Oropouche virus during Brazil\u2019s largest recorded dengue epidemic in 2024","volume":"22","author":"PCS Farias","year":"2025","journal-title":"Virol J"},{"issue":"3","key":"pone.0337522.ref055","doi-asserted-by":"crossref","first-page":"323","DOI":"10.35434\/rcmhnaaa.2022.153.1678","article-title":"Arboviral diseases and monkeypox \u2013 An epidemiological overlapping differential diagnosis?","volume":"15","author":"AJ Rodriguez-Morales","year":"2022","journal-title":"Rev Cuerpo Med HNAAA"},{"issue":"2","key":"pone.0337522.ref056","doi-asserted-by":"crossref","DOI":"10.1002\/rmv.2521","article-title":"Clinical manifestations of dengue, Zika and chikungunya in the Pacific Islands: A systematic review and meta-analysis","volume":"34","author":"S Kharwadkar","year":"2024","journal-title":"Rev Med Virol"},{"key":"pone.0337522.ref057","article-title":"Dengue and Oropouche virus co-infection in a traveller from Cuba to Portugal","author":"L Z\u00e9-Z\u00e9","year":"2025","journal-title":"J Travel Med"},{"issue":"8","key":"pone.0337522.ref058","article-title":"Knowledge and attitude towards mpox: Systematic review and meta-analysis","volume":"19","author":"DA Le\u00f3n-Figueroa","year":"2024","journal-title":"PLoS One"},{"issue":"1","key":"pone.0337522.ref059","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s12889-023-17473-y","article-title":"Prevalence of intentions to receive monkeypox vaccine. A systematic review and meta-analysis","volume":"24","author":"DA Le\u00f3n-Figueroa","year":"2024","journal-title":"BMC Public Health"},{"issue":"1","key":"pone.0337522.ref060","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1186\/s12889-024-17741-5","article-title":"Sources of information on monkeypox virus infection. A systematic review with meta-analysis","volume":"24","author":"DA Le\u00f3n-Figueroa","year":"2024","journal-title":"BMC Public Health"}],"updated-by":[{"DOI":"10.1371\/journal.pone.0350951","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000}}],"container-title":["PLOS One"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0337522","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T18:42:34Z","timestamp":1764873754000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0337522"}},"subtitle":[],"editor":[{"given":"Victoria","family":"Pando-Robles","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,12,4]]},"references-count":60,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2025,12,4]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0337522","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,4]]}}}