{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T19:23:56Z","timestamp":1765567436442,"version":"3.48.0"},"reference-count":26,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sex workers are often considered at elevated risk for sexually transmitted infections (STIs). This pilot study describes the socio\u2011epidemiological characteristics of registered sex workers in a rural German setting, estimates the prevalence of four STIs (HIV, hepatitis B [HBV], hepatitis C [HCV], and syphilis [lues]), compares these with the local population, and assesses HBV immunization coverage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Under \u00a710 of the Prostitute Protection Act (ProstSchG), annual health consultations are mandatory; voluntary serologic testing is permitted under \u00a719 of the Infection Protection Act. We conducted a retrospective observational monocentric pilot study using routine consultation records and voluntary serologic results from the Public Health Service (PHS) of Landshut (2017\u20132021). In total, 523 consultations were documented; 99 blood samples from 48 registered sex workers (2019\u20132021) were analyzed. Primary screening assays were followed by confirmatory tests when indicated. Crude point\/period prevalences and 95% confidence intervals (95% CI) were calculated. HBV immunization was defined according to Standing Committee on Vaccination (STIKO) recommendations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The cohort was predominantly female (n\u2009=\u200947; 97.9%), mean age 34.8\u2009\u00b1\u200911.2 years; 85.3% (n\u2009=\u200941) had a migration background (n\u2009=\u200927; 56.3% from Eastern EU countries). No acute HIV, HBV, or HCV infection was detected. Evidence of past HBV infection (anti\u2011HBc) was found in n\u2009=\u20097 (14.6%; 95% CI: 6.8\u201326.5), past HCV in n\u2009=\u20091 (2.1%; 95% CI: 0.2\u20139.3). Syphilis serology was reactive in 12.5% (n\u2009=\u20096), with n\u2009=\u20092 (4.2%; 95% CI: 0.9\u201312.7) meeting criteria for treatment\u2011requiring infection. HBV vaccine\u2011induced immunity was documented in 43.8%; only 29.2% achieved titers \u2265100 mIU\/ml. Compared with regional surveillance data, the prevalence of acute notifiable STIs among sex workers was not increased.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this rural setting, acute notifiable STIs were uncommon among registered sex workers, while past HBV infection and suboptimal HBV immunization were frequent. Public health efforts should prioritize HBV vaccination and syphilis prevention or treatment, and expand low\u2011threshold, trusted services tailored to this workforce.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0338710","type":"journal-article","created":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T18:25:27Z","timestamp":1765563927000},"page":"e0338710","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of sexually transmitted infections and immunization status among registered sex workers: A pilot study in lower Bavaria, Germany"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6699-8377","authenticated-orcid":true,"given":"Fabian","family":"Standl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lena","family":"Senger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heribert","family":"Stich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2025,12,12]]},"reference":[{"issue":"4","key":"pone.0338710.ref001","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1007\/s11553-019-00716-5","article-title":"Gesundheit und prostitution in deutschland: anforderungen an die pr\u00e4ventionsarbeit auf basis eines systematischen reviews","volume":"14","author":"H Eger","year":"2019","journal-title":"Pr\u00e4v Gesundheitsf"},{"key":"pone.0338710.ref002","article-title":"Risk factors for the acquisition of sexually transmitted infections in sex workers: a systematic review","volume":"98","author":"A Jim\u00e9nez-Mor\u00f3n","year":"2024","journal-title":"Rev Esp Salud Publica"},{"key":"pone.0338710.ref003","volume-title":"Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften e.V. 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