{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T14:08:01Z","timestamp":1781014081567,"version":"3.54.1"},"reference-count":33,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:00:00Z","timestamp":1767052800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["PHRGNIG24jul-0002"],"award-info":[{"award-number":["PHRGNIG24jul-0002"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019579","name":"SingHealth","doi-asserted-by":"publisher","award":["AM-HEARTS AM\/HRT048\/2025"],"award-info":[{"award-number":["AM-HEARTS AM\/HRT048\/2025"]}],"id":[{"id":"10.13039\/100019579","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019579","name":"SingHealth","doi-asserted-by":"publisher","award":["Pitch-For-Funds 03\/FY2024\/P2\/26-A148"],"award-info":[{"award-number":["Pitch-For-Funds 03\/FY2024\/P2\/26-A148"]}],"id":[{"id":"10.13039\/100019579","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"\n Objective<\/jats:title>\n We aimed to provide an up-to-date synthesis of the effectiveness of patient reported outcome measures (PROMs) to self-monitor symptoms compared to conventional follow-up care in rheumatic disease patients. The effect of providing feedback via PROMs was also evaluated.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n This review was guided by the Preferred Reporting Items for Systematic review and Meta-Analysis guidelines. Articles published before December 2024 were retrieved from PubMed\n \u00ae<\/jats:sup>\n , Cochrane Library\n \u00ae<\/jats:sup>\n , Embase\n \u00ae<\/jats:sup>\n , and PsycINFO\n \u00ae<\/jats:sup>\n (Ovid). Studies were included if they (1) compared PROMs against no PROMs use, or (2) or if they utilized PROMs as an intervention with feedback provided to healthcare professionals or patients for comparison against PROMs use without feedback. Non-English articles and abstract-only articles were excluded. Results were synthesized in a narrative manner. Methodological quality was assessed using the Risk of Bias tool and the Risk of Bias in Non-randomized Studies of Interventions tool.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n A total of 18, 159 articles were screened, and 9 articles were included. All 9 studies reported on the use of PROMs as an intervention against a control where no PROMs were used. 4 of the studies included reported improvements in symptom control; 1 study observed improvement in health-related quality of life (HRQoL) when PROMs were used. High patient satisfaction was observed in 5 studies, but the results were statistically insignificant. 1 found that PROMs use facilitated shared decision making. 3 studies reported on clinic visits with mixed results. No studies reported on survival\/mortality. Out of the 9 studies, 2 studies compared PROMs with feedback to patients and\/or healthcare professionals against PROMS without feedback. There was conflicting evidence whether PROMs with feedback improved patient satisfaction in clinical care. Three studies were identified to be of moderate to high risk of bias.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The use of PROMs self-symptom monitoring may contribute to improving symptom control, HRQoL, patient perception, promote shared decision making, and reduce clinic visits. Our study may have limited generalizability to other rheumatic disease beyond RA as most of our study is in rheumatoid arthritis. More studies in other rheumatic diseases are needed.<\/jats:p>\n <\/jats:sec>\n \n Registration<\/jats:title>\n \n The protocol was registered in OpenSci Framework (\n https:\/\/doi.org\/10.17605\/OSF.IO\/ZU9XM<\/jats:ext-link>\n ).\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1371\/journal.pone.0338935","type":"journal-article","created":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T19:03:25Z","timestamp":1767121405000},"page":"e0338935","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["A systematic review of the effectiveness of self-symptoms monitoring with Patient Reported Outcome Measures in rheumatic disease patients"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7802-9696","authenticated-orcid":true,"given":"Yu Heng","family":"Kwan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livia","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pui Kim","family":"Ang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhonghui","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei Xin","family":"Chong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sungwon","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei Shi","family":"Ong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charmaine T. M.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvana X.","family":"Choo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying Ying","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Thumboo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Warren","family":"Fong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,12,30]]},"reference":[{"issue":"7","key":"pone.0338935.ref001","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0253615","article-title":"Electronic patient-reported outcome measures using mobile health technology in rheumatology: a scoping review","volume":"16","author":"J Shelton","year":"2021","journal-title":"PLoS One"},{"issue":"4","key":"pone.0338935.ref002","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1111\/hex.13254","article-title":"Patient-reported outcome measures (PROMs): a review of generic and condition-specific measures and a discussion of trends and issues","volume":"24","author":"K Churruca","year":"2021","journal-title":"Health Expect"},{"issue":"6","key":"pone.0338935.ref003","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1111\/hex.12573","article-title":"Asking what matters: the relevance and use of patient-reported outcome measures that were developed without patient involvement","volume":"20","author":"B Wiering","year":"2017","journal-title":"Health Expect"},{"key":"pone.0338935.ref004","unstructured":"NHS England. Using an app to remotely monitor rheumatoid arthritis (RA). [cited 2024 May 11]. Available from: https:\/\/transform.england.nhs.uk\/key-tools-and-info\/digital-playbooks\/rheumatology-digital-playbook\/using-an-app-to-remotely-monitor-rheumatoid-arthritis\/"},{"issue":"1","key":"pone.0338935.ref005","first-page":"14","article-title":"An assessment of patient waiting and consultation time in a primary healthcare clinic","volume":"12","author":"BA Ahmad","year":"2017","journal-title":"Malays Fam Physician"},{"issue":"2","key":"pone.0338935.ref006","doi-asserted-by":"crossref","DOI":"10.1136\/rmdopen-2016-000302","article-title":"Improving inflammatory arthritis management through tighter monitoring of patients and the use of innovative electronic tools","volume":"2","author":"P van Riel","year":"2016","journal-title":"RMD Open"},{"issue":"1","key":"pone.0338935.ref007","doi-asserted-by":"crossref","DOI":"10.2196\/15588","article-title":"Benefits and disadvantages of electronic patient-reported outcome measures: systematic review","volume":"3","author":"J Meirte","year":"2020","journal-title":"JMIR Perioper Med"},{"issue":"2","key":"pone.0338935.ref008","article-title":"The influence of collecting patient-reported outcome measures on visit satisfaction in rheumatology clinics","volume":"4","author":"R Honomichl","year":"2020","journal-title":"Rheumatol Adv Pract"},{"issue":"8","key":"pone.0338935.ref009","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1007\/s00296-021-04907-2","article-title":"Tele-health interventions to support self-management in adults with rheumatoid arthritis: a systematic review","volume":"41","author":"A MacIver","year":"2021","journal-title":"Rheumatol Int"},{"issue":"10","key":"pone.0338935.ref010","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/j.jval.2024.05.013","article-title":"Patient-reported outcome measures as an intervention: a comprehensive overview of systematic reviews on the effects of feedback","volume":"27","author":"L Wittich","year":"2024","journal-title":"Value Health"},{"issue":"2","key":"pone.0338935.ref011","first-page":"573","article-title":"Patient outcomes, patient experiences and process indicators associated with the routine use of patient-reported outcome measures (PROMs) in cancer care: a systematic review","volume":"29","author":"C Graupner","year":"2021","journal-title":"Support Care Cancer"},{"issue":"1","key":"pone.0338935.ref012","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/s41687-023-00578-8","article-title":"Effectiveness of routine provision of feedback from patient-reported outcome measurements for cancer care improvement: a systematic review and meta-analysis","volume":"7","author":"S-C Lu","year":"2023","journal-title":"J Patient Rep Outcomes"},{"key":"pone.0338935.ref013","doi-asserted-by":"crossref","first-page":"364","DOI":"10.3389\/fped.2020.00364","article-title":"Patient-reported outcome measures in routine pediatric clinical care: a systematic review","volume":"8","author":"S Bele","year":"2020","journal-title":"Front Pediatr"},{"issue":"11","key":"pone.0338935.ref014","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1002\/art.42559","article-title":"The clinical impact of electronic patient-reported outcome measures in the remote monitoring of inflammatory arthritis: a systematic review and meta-analysis","volume":"75","author":"N Arumalla","year":"2023","journal-title":"Arthritis Rheumatol"},{"issue":"3","key":"pone.0338935.ref015","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.semarthrit.2018.03.006","article-title":"The use of routinely collected patient-reported outcome measures in rheumatoid arthritis","volume":"48","author":"M Hiligsmann","year":"2018","journal-title":"Semin Arthritis Rheum"},{"issue":"7","key":"pone.0338935.ref016","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1093\/rheumatology\/kez506","article-title":"Patient-reported outcomes in RA care improve patient communication, decision-making, satisfaction and confidence: qualitative results","volume":"59","author":"SJ Bartlett","year":"2020","journal-title":"Rheumatology (Oxford)"},{"issue":"4","key":"pone.0338935.ref017","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1007\/s11136-020-02692-2","article-title":"Patient-reported experience with patient-reported outcome measures in adult patients seen in rheumatology clinics","volume":"30","author":"BR Lapin","year":"2021","journal-title":"Qual Life Res"},{"key":"pone.0338935.ref018","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"MJ Page","year":"2021","journal-title":"BMJ"},{"key":"pone.0338935.ref019","unstructured":"Kwan YH, Ang PK, Oh ECL. Effectiveness of self-symptom monitoring using PROMs in patients with chronic diseases: protocol for a systematic review: OpenScience Framework; 2023. Available from: osf.io\/zu9xm"},{"key":"pone.0338935.ref020","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"JAC Sterne","year":"2019","journal-title":"BMJ"},{"key":"pone.0338935.ref021","article-title":"ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"JA Sterne","year":"2016","journal-title":"BMJ"},{"key":"pone.0338935.ref022","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1186\/s12891-016-1002-2","article-title":"Effectiveness of a telemonitoring intensive strategy in early rheumatoid arthritis: comparison with the conventional management approach","volume":"17","author":"F Salaffi","year":"2016","journal-title":"BMC Musculoskelet Disord"},{"issue":"4","key":"pone.0338935.ref023","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1093\/rheumatology\/keaa462","article-title":"A randomized prospective open-label controlled trial comparing the performance of a connected monitoring interface versus physical routine monitoring in patients with rheumatoid arthritis","volume":"60","author":"Y-M Pers","year":"2021","journal-title":"Rheumatology (Oxford)"},{"issue":"11","key":"pone.0338935.ref024","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1002\/art.42292","article-title":"Smartphone-assisted patient-initiated care versus usual care in patients with rheumatoid arthritis and low disease activity: a randomized controlled trial","volume":"74","author":"B Seppen","year":"2022","journal-title":"Arthritis Rheumatol"},{"issue":"6","key":"pone.0338935.ref025","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.jbspin.2017.11.015","article-title":"An e-health interactive self-assessment website (Sanoia\u00ae) in rheumatoid arthritis. A 12-month randomized controlled trial in 320 patients","volume":"85","author":"L Gossec","year":"2018","journal-title":"Joint Bone Spine"},{"issue":"4","key":"pone.0338935.ref026","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1007\/s11999.0000000000000069","article-title":"Feedback to patients about patient-reported outcomes does not improve empowerment or satisfaction","volume":"476","author":"L Ackermans","year":"2018","journal-title":"Clin Orthop Relat Res"},{"issue":"1","key":"pone.0338935.ref027","doi-asserted-by":"crossref","DOI":"10.1136\/rmdopen-2021-001566","article-title":"Impact of assessing patient-reported outcomes with mobile apps on patient-provider interaction","volume":"7","author":"Y Shaw","year":"2021","journal-title":"RMD Open"},{"issue":"5","key":"pone.0338935.ref028","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1002\/art.42774","article-title":"A mobile health application integrated in the electronic health record for rheumatoid arthritis patient-reported outcomes: a controlled interrupted time-series analysis of impact on visit efficiency","volume":"76","author":"DH Solomon","year":"2024","journal-title":"Arthritis Rheumatol"},{"issue":"4","key":"pone.0338935.ref029","article-title":"Management of rheumatoid arthritis with a digital health application: a multicenter, pragmatic randomized clinical trial","volume":"6","author":"C Li","year":"2023","journal-title":"JAMA Netw Open"},{"issue":"8","key":"pone.0338935.ref030","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1002\/art.41686","article-title":"Outcomes of a mobile app to monitor patient-reported outcomes in rheumatoid arthritis: a randomized controlled trial","volume":"73","author":"YC Lee","year":"2021","journal-title":"Arthritis Rheumatol"},{"issue":"11","key":"pone.0338935.ref031","doi-asserted-by":"crossref","first-page":"3576","DOI":"10.1093\/rheumatology\/kead106","article-title":"Mortality estimates and excess mortality in rheumatoid arthritis","volume":"62","author":"RJ Black","year":"2023","journal-title":"Rheumatology (Oxford)"},{"issue":"4","key":"pone.0338935.ref032","doi-asserted-by":"crossref","first-page":"101939","DOI":"10.1016\/j.berh.2024.101939","article-title":"The communication GAP between patients and clinicians and the importance of patient reported outcomes in Systemic Lupus Erythematosus","volume":"37","author":"E Elefante","year":"2023","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"pone.0338935.ref033","doi-asserted-by":"crossref","unstructured":"Young AA-O, Rudy B, Volkmann EA-O. Living with systemic sclerosis: A patient and physician perspective. (2189-6576 (Print)). 2023.","DOI":"10.1007\/s40744-023-00555-z"}],"container-title":["PLOS One"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0338935","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T19:03:32Z","timestamp":1767121412000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0338935"}},"subtitle":[],"editor":[{"given":"Thomas","family":"Rulleau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,12,30]]},"references-count":33,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2025,12,30]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0338935","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,30]]}}}