{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T18:49:15Z","timestamp":1775846955903,"version":"3.50.1"},"reference-count":32,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aims to develop an automatic weighing device based on embedded technology for accurately monitoring the consumption of various cleaning agents during each cleaning cycle of mechanical cleaning equipment used in the Central Sterile Supply Department (CSSD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The hardware of the automatic weighing device included an ESP32 development board, HX711 module, infrared sensor, load cell, and display screen, with the circuit having been designed using a printed circuit board. After each cleaning cycle of the mechanical cleaning equipment, the device automatically calculated the consumption of cleaning agents. To validate its accuracy, the device\u2019s measurements were compared with the gold standard (volumetric measurement method). Additionally, the device was installed on a washer-disinfector for practical application testing to evaluate its performance. A mobile APP was also developed to enable real-time synchronization of data displayed on the screen of the automatic weighing device.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 20 comparative tests were conducted between the automatic weighing device and the volumetric method. The mean difference in measured cleaning agent consumption was 0.16\u2009mL (95% CI: \u22120.24 to 0.56), with the interquartile range of absolute differences being 0.54 mL\u20131.06\u2009mL. The expected consumption values for enzymatic and alkaline cleaning agents for the washer-disinfector were 100\u2009g and 60\u2009g per cycle, respectively. During the first 52 cleaning cycles, the average consumption of enzymatic detergent was 88.46\u2009g (95% CI: 85.81\u201391.18), and that of alkaline detergent was 49.45\u2009g (95% CI: 48.51\u201350.40), both significantly below the expected values. After replacing the peristaltic pump hose, a subsequent test of 55 cleaning cycles showed average consumptions of 97.70\u2009g (95% CI: 96.40\u201399.00) for enzymatic detergent and 59.67\u2009g (95% CI: 58.90\u201360.44) for alkaline detergent, both closely approaching the expected values.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The automatic weighing device demonstrated reliable measurement performance, simple structure, high compatibility, and stable operation. It is easy to install, use, and maintain, offering a feasible and scientifically effective technical solution for accurately monitoring cleaning agent consumption in CSSD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0341030","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T17:51:31Z","timestamp":1775843491000},"page":"e0341030","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["An automatic weighing device for measuring the consumption of cleaning agents in mechanical cleaning equipment"],"prefix":"10.1371","volume":"21","author":[{"given":"Wei","family":"Zheng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Gui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1543-8887","authenticated-orcid":true,"given":"Yafei","family":"Kong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2026,4,10]]},"reference":[{"issue":"1","key":"pone.0341030.ref001","first-page":"33","article-title":"Optimization of a Sterile Processing Department Using Lean Six Sigma Methodology, Staffing Enhancement, and Capital Investment","volume":"51","author":"ME Natarus","year":"2025","journal-title":"Jt Comm J Qual Patient Saf"},{"key":"pone.0341030.ref002","doi-asserted-by":"crossref","first-page":"1553113","DOI":"10.3389\/fpubh.2025.1553113","article-title":"Improving precision instrument cleaning with a quality control module: implementation and outcomes","volume":"13","author":"J Xiong","year":"2025","journal-title":"Front Public Health"},{"issue":"1","key":"pone.0341030.ref003","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0280595","article-title":"Analysis of microbial contamination during use and reprocessing of surgical instruments and sterile packaging systems","volume":"18","author":"L Dreikausen","year":"2023","journal-title":"PLoS One"},{"key":"pone.0341030.ref004","volume-title":"WS 310.2: Central sterile supply department. 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