{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T16:19:58Z","timestamp":1792081198682,"version":"4.4.0"},"reference-count":32,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:00:00Z","timestamp":1770163200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["170313"],"award-info":[{"award-number":["170313"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Growing research and clinical attention to loneliness has led to a wide range of available measures; however, few studies directly compare different loneliness measures within the same population. Measures include single-item, direct questions and indirect, multi-item scales. This study compared responses and respondent characteristics between a direct single-item loneliness question and an indirect multi-item scale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a cross-sectional analysis of population-based survey data from the Canadian Longitudinal Study on Aging (CLSA). The sample included baseline (2010\u22122015) and follow-up 1 respondents (2015\u22122018) from both the Tracking (computer-assisted telephone interviews) and Comprehensive (in-home assessment) cohorts (n\u2009=\u200943,235). Loneliness was assessed using a direct single-item question from the Center for Epidemiological Studies Depression Scale (CES-D-10) and the 3-item Loneliness Scale. We categorized loneliness using ordinal (not lonely, moderately lonely, severely lonely) and dichotomous (lonely\/not lonely) classifications. Unweighted descriptive statistics were used to examine demographic, social, and health characteristics across measures and response categories.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 43,235 CLSA respondents, 14% (n\u2009=\u20095,848) were identified by both the single-item question and the scale as lonely, 67% (n\u2009=\u200928,998) were identified as not lonely by both, leaving 19% classified differently based on measure. Individuals identified as lonely respondents by both measures were more often older, women, less educated, and had lower income. Those classified as severely lonely on the single item but not lonely on the scale were older than other groups. In contrast, respondents who were moderately lonely on the single-item question tended to be married, report higher income, and have greater social contact.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The direct single-item question and the indirect multi-item scale provided comparable overall classifications of loneliness in our CLSA sample. However, respondent characteristics varied across the more granular response categories, highlighting the importance of measure selection depending on study aims.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0341572","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T18:31:46Z","timestamp":1770229906000},"page":"e0341572","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":4,"title":["Single-item versus scale: Comparing respondent demographic, social, and health characteristics by measure of loneliness using the Canadian Longitudinal Study on Aging (CLSA) data"],"prefix":"10.1371","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9602-3060","authenticated-orcid":true,"given":"Stephanie A.","family":"Chamberlain","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren E.","family":"Griffith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel D.","family":"Savage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse","family":"Batara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenting","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Gruneir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"issue":"2","key":"pone.0341572.ref001","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1177\/1745691614568352","article-title":"Loneliness and social isolation as risk factors for mortality: a meta-analytic review","volume":"10","author":"J Holt-Lunstad","year":"2015","journal-title":"Perspect Psychol Sci"},{"issue":"15","key":"pone.0341572.ref002","doi-asserted-by":"crossref","first-page":"5797","DOI":"10.1073\/pnas.1219686110","article-title":"Social isolation, loneliness, and all-cause mortality in older men and women","volume":"110","author":"A Steptoe","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"13","key":"pone.0341572.ref003","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1177\/2047487318792696","article-title":"Loneliness, social isolation and risk of cardiovascular disease in the English longitudinal study of ageing","volume":"25","author":"NK Valtorta","year":"2018","journal-title":"Eur J Prev Cardiol"},{"key":"pone.0341572.ref004","doi-asserted-by":"crossref","DOI":"10.1136\/bmj-2021-067068","article-title":"The prevalence of loneliness across 113 countries: systematic review and meta-analysis","volume":"376","author":"DL Surkalim","year":"2022","journal-title":"BMJ"},{"issue":"11","key":"pone.0341572.ref005","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1038\/s41386-021-01058-7","article-title":"Neurobiology of loneliness: a systematic review","volume":"46","author":"JA Lam","year":"2021","journal-title":"Neuropsychopharmacology"},{"issue":"1","key":"pone.0341572.ref006","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1177\/1088868319850738","article-title":"The stability and change of loneliness across the life span: a meta-analysis of longitudinal studies","volume":"24","author":"M Mund","year":"2020","journal-title":"Pers Soc Psychol Rev"},{"key":"pone.0341572.ref007","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.puhe.2017.07.035","article-title":"An overview of systematic reviews on the public health consequences of social isolation and loneliness","volume":"152","author":"N Leigh-Hunt","year":"2017","journal-title":"Public Health"},{"issue":"4","key":"pone.0341572.ref008","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2015-010799","article-title":"Loneliness, social isolation and social relationships: what are we measuring? 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