{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T18:53:33Z","timestamp":1785524013074,"version":"3.56.0"},"reference-count":39,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100017170","name":"Thailand Science Research and Innovation","doi-asserted-by":"publisher","award":["69A150000061"],"award-info":[{"award-number":["69A150000061"]}],"id":[{"id":"10.13039\/501100017170","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>Social support, which is an essential aspect influencing health, has resulted in the development of several approaches for assessment in cancer patients. The Illness-Specific Social Support Scale Short Version-8 (ISSS-8) effectively evaluates social support among diverse patient demographics; however, its psychometric validity has yet to be established in Asian cultural contexts. The objectives of this study were to translate and culturally adapt the ISSS-8 for the Thai setting and to assess its psychometric properties in patients with hematological malignancies (HMs). This study employed a convenience sampling method to select patients with HMs undergoing hospitalization at three tertiary institutions in Northeastern Thailand. Psychometric testing was conducted following the translation and cross-cultural adaptation of the ISSS-8 into Thai. A total of 350 patients were recruited. Participants were randomly divided into two groups for exploratory factor analysis (EFA) (n\u2009=\u2009200) and confirmatory factor analysis (CFA) (n\u2009=\u2009150). The EFA of the eight items yielded a loading from a two-factor model comprising Positive Support and Detrimental Interactions, which explained 82.44% of the variance. Cronbach\u2019s alpha (0.80) and item\u2013total correlations (rho\u2009=\u20090.33\u20130.65) demonstrated acceptable reliability of the ISSS-8, while test\u2013retest reliability was high (ICC\u2009=\u20090.924-\u20130.934). The average variance extracted (AVE) demonstrated convergent validity for all ISSS-8 subscales, with AVEs ranging from 0.76 to 0.80. Moreover, the total ISSS-8 scale demonstrated a statistically significant but weak positive correlation with the Stanford Inventory of Cancer Patient Adjustment (r\u2009=\u20090.244, p\u2009&lt;\u20090.001), while the Detrimental Interactions subscale was significantly and weak negatively correlated with it (r\u2009=\u20090.237, p\u2009&lt;\u20090.001). These findings suggest that the ISSS-8 captures distinct psychosocial and illness-specific relational constructs that differ from coping self-efficacy and psychological adjustment measured by the SICPA. The ISSS-8 is a short, accurate, and valid instrument for measuring social support in Thai patients with HMs. As a result, healthcare professionals can use the ISSS-8 to assess social support in both research and clinical settings. The findings emphasize the necessity of integrating social support evaluation into cancer management and family-centered care, thereby supporting comprehensive and adaptive healthcare delivery in Thailand.<\/jats:p>","DOI":"10.1371\/journal.pone.0341756","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T17:31:16Z","timestamp":1785519076000},"page":"e0341756","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Psychometric properties of the Thai version of the Illness-Specific Social Support Scale Short Version-8 (ISSS-8) among hematological malignancy patients in the Northeastern region of Thailand: A multicenter study"],"prefix":"10.1371","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9557-2199","authenticated-orcid":true,"given":"Ueamporn","family":"Summart","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6893-0317","authenticated-orcid":true,"given":"Monthida","family":"Sangruangake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaliya","family":"Wamaloon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Acharaporn","family":"Moungmultri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhamad 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