{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T07:27:33Z","timestamp":1788852453576,"version":"build-2803163510"},"reference-count":36,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the National Key Research and Development Program of China","award":["2024YFC3506301"],"award-info":[{"award-number":["2024YFC3506301"]}]},{"name":"Wang Qi's National Master of Traditional Chinese Medicine Inheritance Studio","award":["DFRCYJ-2024A-001"],"award-info":[{"award-number":["DFRCYJ-2024A-001"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>\n                    Serum uric acid (UA) is linked to non-alcoholic fatty liver disease (NAFLD), but its role in hypertensive populations remains unclear. This cross-sectional study investigated their association in 1,058 patients with hypertension. Multivariate logistic regression analysis confirmed that UA was independently correlated with NAFLD, whether as a continuous variable or a categorical variable. According to the fully adjusted model, the risk of NAFLD increased by 0.2%, 347.2% and 91.7% for each unit increase in UA, Log\n                    <jats:sub>10<\/jats:sub>\n                    UA and LnUA, respectively (P\u2009&lt;\u20090.05). Multivariate stratified analysis revealed that UA increased the risk of NAFLD in specific subgroups, including males, individuals aged 70\u201379 years, non-smokers, those without diabetes, and obese individuals (P\u2009&lt;\u20090.05). Receiver operating characteristic (ROC) analysis indicated that UA could not only predict the occurrence of NAFLD but also improve the predictive value of the baseline model for NAFLD (UA, AUC: 0.588; baseline model, AUC: 0.770; baseline model\u2009+\u2009UA, AUC: 0.772). In conclusion, UA is significantly associated with NAFLD in patients with hypertension and may serve as a predictive risk indicator.\n                  <\/jats:p>","DOI":"10.1371\/journal.pone.0341949","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T18:26:42Z","timestamp":1769711202000},"page":"e0341949","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Association between uric acid and non-alcoholic fatty liver disease in patients with 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