{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T08:33:22Z","timestamp":1770280402992,"version":"3.49.0"},"reference-count":67,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:00:00Z","timestamp":1770163200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","award":["818070"],"award-info":[{"award-number":["818070"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]},{"name":"small grant funding 2021 by the Institute of Mental Health"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>Dysregulations in interoception have been associated with mental health disorders including eating and somatic symptom disorders. The present study addresses the feasibility and acceptability of a novel, behavioural intervention (InMe) in a healthy sample with low, self-reported interoception. The efficacy of the InMe intervention against an active control arm was tested in a randomised controlled trial (RCT) reported elsewhere, while the feasibility and acceptability of InMe were assessed in parallel and are fully reported here. Participants were randomly assigned to the intervention arm (InMe) or active control arm and stratified according to their self-reported gender and a cut-off score from the Eating Disorders Questionnaire (EDE-Q). Feasibility and accessibility measures included self-report scales and questionnaires, assessor checklists and ratings, as well as behavioural and physiological responses. Data was gathered from a total of 102 participants and encompassed trial recruitment and retention rates, the suitability of measurement tools, as well as the feasibility and acceptability of stressors, interventions and other trial procedures. The study found satisfactory feasibility in recruitment procedures, trial measurement tools, and intervention procedures. Participants perceived the intervention as acceptable, though minor adjustments for trial optimisation were identified. Overall, this feasibility study provided promising evidence regarding the acceptability and feasibility of an interoception based intervention in a RCT context. These findings offer valuable insights particularly for the design of future clinical trials for testing the efficacy of this intervention further in clinical populations.<\/jats:p>","DOI":"10.1371\/journal.pone.0342307","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T18:33:33Z","timestamp":1770230013000},"page":"e0342307","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility and acceptability outcomes of the InMe trial - a randomised controlled trial in participants with subclinical eating and somatic symptom disorders"],"prefix":"10.1371","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1875-309X","authenticated-orcid":true,"given":"Marina","family":"Bobou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michal","family":"Tanzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1620-4190","authenticated-orcid":true,"given":"Alkistis","family":"Saramandi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9698-3405","authenticated-orcid":true,"given":"Caroline","family":"Selai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aikaterini","family":"Fotopoulou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"issue":"6","key":"pone.0342307.ref001","first-page":"501","article-title":"Interoception and mental health: a roadmap","volume":"3","author":"SS Khalsa","year":"2018","journal-title":"Biological Psychiatry: Cognitive Neurosci Neuroimaging"},{"key":"pone.0342307.ref002","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.neubiorev.2021.07.036","article-title":"Atypical interoception as a common risk factor for psychopathology: A review","volume":"130","author":"R Brewer","year":"2021","journal-title":"Neurosci Biobehav Rev"},{"key":"pone.0342307.ref003","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3389\/fpsyt.2016.00121","article-title":"Can interoception improve the pragmatic search for biomarkers in psychiatry?","volume":"7","author":"SS Khalsa","year":"2016","journal-title":"Front Psychiatry"},{"issue":"1","key":"pone.0342307.ref004","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1017\/S0033291717001635","article-title":"Altered interoceptive activation before, during, and after aversive breathing load in women remitted from anorexia nervosa","volume":"48","author":"LA Berner","year":"2018","journal-title":"Psychol Med"},{"issue":"7","key":"pone.0342307.ref005","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1002\/eat.22387","article-title":"Altered interoceptive awareness in anorexia nervosa: Effects of meal anticipation, consumption and bodily arousal","volume":"48","author":"SS Khalsa","year":"2015","journal-title":"Int J Eat Disord"},{"key":"pone.0342307.ref006","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.neubiorev.2019.08.020","article-title":"Interoception and disordered eating: a systematic review","volume":"107","author":"E Martin","year":"2019","journal-title":"Neurosci Biobehav Rev"},{"key":"pone.0342307.ref007","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s13030-020-00179-7","article-title":"Effects of interoceptive training on decision making, anxiety, and somatic symptoms","volume":"14","author":"A Sugawara","year":"2020","journal-title":"Biopsychosoc Med"},{"issue":"8","key":"pone.0342307.ref008","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0271717","article-title":"Interoceptive accuracy and bias in somatic symptom disorder, illness anxiety disorder, and functional syndromes: A systematic review and meta-analysis","volume":"17","author":"C Wolters","year":"2022","journal-title":"PLoS One"},{"issue":"4","key":"pone.0342307.ref009","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1080\/13546805.2020.1791061","article-title":"Dissociation and interoception in functional neurological disorder","volume":"25","author":"S Pick","year":"2020","journal-title":"Cogn Neuropsychiatry"},{"key":"pone.0342307.ref010","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1515\/9781400852727-004","article-title":"An Introduction to Interoception","volume-title":"How Do You Feel?: An Interoceptive Moment with Your Neurobiological Self","author":"AD Craig","year":"2015"},{"key":"pone.0342307.ref011","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.jad.2018.12.101","article-title":"Relationship between interoception and emotion regulation: New evidence from mixed methods","volume":"246","author":"G Zamariola","year":"2019","journal-title":"J Affect Disord"},{"issue":"10","key":"pone.0342307.ref012","doi-asserted-by":"crossref","first-page":"150664","DOI":"10.1098\/rsos.150664","article-title":"Alexithymia: a general deficit of interoception","volume":"3","author":"R Brewer","year":"2016","journal-title":"R Soc Open Sci"},{"issue":"8","key":"pone.0342307.ref013","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1021\/cn5001028","article-title":"Interoception and learning: import to understanding and treating diseases and psychopathologies","volume":"5","author":"RA Bevins","year":"2014","journal-title":"ACS Chem Neurosci"},{"issue":"4","key":"pone.0342307.ref014","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.eatbeh.2008.02.001","article-title":"Reduced perception of bodily signals in anorexia nervosa","volume":"9","author":"O Pollatos","year":"2008","journal-title":"Eat Behav"},{"issue":"1","key":"pone.0342307.ref015","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1186\/s40337-023-00914-9","article-title":"Exploration of interoceptive capabilities in avoidant\/restrictive food intake disorder and anorexia nervosa","volume":"11","author":"N Datta","year":"2023","journal-title":"J Eat Disord"},{"key":"pone.0342307.ref016","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.neubiorev.2017.01.015","article-title":"Symptoms and the body: Taking the inferential leap","volume":"74","author":"O Van den Bergh","year":"2017","journal-title":"Neurosci Biobehav Rev"},{"key":"pone.0342307.ref017","doi-asserted-by":"crossref","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"2013","edition":"5"},{"issue":"1","key":"pone.0342307.ref018","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.tins.2020.09.010","article-title":"Interventions and manipulations of interoception","volume":"44","author":"HY Weng","year":"2021","journal-title":"Trends Neurosci"},{"issue":"8","key":"pone.0342307.ref019","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.brat.2011.05.004","article-title":"Randomised controlled trial of a guided self-help treatment on the Internet for binge eating disorder","volume":"49","author":"I Carrard","year":"2011","journal-title":"Behav Res Ther"},{"issue":"4","key":"pone.0342307.ref020","first-page":"44","article-title":"Randomized, controlled trial of breath therapy for patients with chronic low-back pain","volume":"11","author":"WE Mehling","year":"2005","journal-title":"Altern Ther Health Med"},{"key":"pone.0342307.ref021","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2021.101042","article-title":"Interoceptive training to target anxiety in autistic adults (ADIE): A single-center, superiority randomized controlled trial","volume":"39","author":"L Quadt","year":"2021","journal-title":"eClinicalMedicine"},{"issue":"4","key":"pone.0342307.ref022","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1080\/16506073.2014.916745","article-title":"Aerobic Exercise Reduces Symptoms of Posttraumatic Stress Disorder: A Randomized Controlled Trial","volume":"44","author":"MG Fetzner","year":"2015","journal-title":"Cogn Behav Ther"},{"key":"pone.0342307.ref023","doi-asserted-by":"crossref","first-page":"107201","DOI":"10.1016\/j.neuropsychologia.2019.107201","article-title":"Transcutaneous vagus nerve stimulation improves interoceptive accuracy","volume":"134","author":"V Villani","year":"2019","journal-title":"Neuropsychologia"},{"issue":"1","key":"pone.0342307.ref024","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.ijpsycho.2008.08.010","article-title":"Bolus isoproterenol infusions provide a reliable method for assessing interoceptive awareness","volume":"72","author":"SS Khalsa","year":"2009","journal-title":"Int J Psychophysiol"},{"issue":"6","key":"pone.0342307.ref025","first-page":"851","article-title":"Regional brain activation due to pharmacologically induced adrenergic interoceptive stimulation in humans","volume":"64","author":"OG Cameron","year":"2002","journal-title":"Psychosom Med"},{"issue":"10","key":"pone.0342307.ref026","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1111\/pcn.13576","article-title":"Psychological interventions for interoception in mental health disorders: A systematic review of randomized-controlled trials","volume":"77","author":"N Heim","year":"2023","journal-title":"Psychiatry Clin Neurosci"},{"issue":"5","key":"pone.0342307.ref027","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/j.beth.2021.02.001","article-title":"Reconnecting to Internal Sensation and Experiences: A Pilot Feasibility Study of an Online Intervention to Improve Interoception and Reduce Suicidal Ideation","volume":"52","author":"AR Smith","year":"2021","journal-title":"Behav Ther"},{"key":"pone.0342307.ref028","first-page":"1","article-title":"An interoception-based intervention for improving emotional regulation in children in a special education classroom: feasibility study","author":"K Mahler","year":"2024","journal-title":"Occup Ther Health Care"},{"issue":"5","key":"pone.0342307.ref029","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph18052515","article-title":"Feasibility, acceptability, and outcomes of a yoga-based meditation intervention for hospice professionals to combat burnout","volume":"18","author":"C Heeter","year":"2021","journal-title":"Int J Environ Res Public Health"},{"issue":"1","key":"pone.0342307.ref030","doi-asserted-by":"crossref","first-page":"2306747","DOI":"10.1080\/20008066.2024.2306747","article-title":"The role of interoception in reducing trauma-associated distress: a feasibility study","volume":"15","author":"D Shatrova","year":"2024","journal-title":"Eur J Psychotraumatol"},{"issue":"10","key":"pone.0342307.ref031","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0307690","article-title":"Mind your pain: A single-arm feasibility study to assess a smartphone-based interoceptive attention training for patients with chronic low back pain","volume":"19","author":"WE Mehling","year":"2024","journal-title":"PLoS One"},{"key":"pone.0342307.ref032","article-title":"Understanding the body from the inside: The role of interoceptive belief updating in anorexia nervosa","volume-title":"University College London","author":"A Saramandi","year":"2024"},{"key":"pone.0342307.ref033","doi-asserted-by":"crossref","unstructured":"Tanzer M, et al. Biofeedback and training of interoceptive insight and metacognitive efficacy beliefs (InMe) to improve adaptive interoception: A subclinical randomised controlled trial. OSF Preprints. 2024.","DOI":"10.31219\/osf.io\/y2b4a"},{"key":"pone.0342307.ref034","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.ynstr.2016.11.001","article-title":"The trier social stress test: principles and practice","volume":"6","author":"AP Allen","year":"2017","journal-title":"Neurobiol Stress"},{"key":"pone.0342307.ref035","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1159\/000119004","article-title":"The \u2019Trier Social Stress Test\u2019--a tool for investigating psychobiological stress responses in a laboratory setting","volume":"28","author":"C Kirschbaum","year":"1993","journal-title":"Neuropsychobiology"},{"issue":"5","key":"pone.0342307.ref036","doi-asserted-by":"crossref","first-page":"264","DOI":"10.3109\/03091902.2015.1047536","article-title":"Validation of photoplethysmography as a method to detect heart rate during rest and exercise","volume":"39","author":"DK Spierer","year":"2015","journal-title":"J Med Eng Technol"},{"issue":"7","key":"pone.0342307.ref037","doi-asserted-by":"crossref","first-page":"517","DOI":"10.2165\/00007256-200333070-00004","article-title":"Heart rate monitoring: applications and limitations","volume":"33","author":"J Achten","year":"2003","journal-title":"Sports Med"},{"key":"pone.0342307.ref038","unstructured":"Polar Electro Oy Polar optical heart rate. 2017."},{"issue":"1","key":"pone.0342307.ref039","doi-asserted-by":"crossref","DOI":"10.1136\/bmjsem-2015-000106","article-title":"How accurate are the wrist-based heart rate monitors during walking and running activities? Are they accurate enough?","volume":"2","author":"SE Stahl","year":"2016","journal-title":"BMJ Open Sport Exerc Med"},{"key":"pone.0342307.ref040","unstructured":"Polar Electro Oy. SereneTM breathing exercise. 2019."},{"key":"pone.0342307.ref041","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s10484-014-9253-x","article-title":"Inhalation\/Exhalation ratio modulates the effect of slow breathing on heart rate variability and relaxation","volume":"39","author":"I Van Diest","year":"2014","journal-title":"Appl Psychophysiol Biofeedback"},{"issue":"4","key":"pone.0342307.ref042","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1183\/20734735.009817","article-title":"The physiological effects of slow breathing in the healthy human","volume":"13","author":"MA Russo","year":"2017","journal-title":"Breathe (Sheff)"},{"key":"pone.0342307.ref043","article-title":"Patient and public involvement in developing a therapeutic model based on real time heart biofeedback - InMe trial","author":"M Bobou","year":"2024","journal-title":"OSF Preprints"},{"key":"pone.0342307.ref044","first-page":"1","article-title":"Biofeedback and training of interoceptive insight and metacognitive efficacy beliefs to improve adaptive interoception: A subclinical randomised controlled trial","author":"M Tanzer","year":"2025","journal-title":"Psychother Psychosom"},{"issue":"4","key":"pone.0342307.ref045","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1207\/s15327752jpa5304_16","article-title":"The Body Awareness Questionnaire: Reliability and Validity","volume":"53","author":"SA Shields","year":"1989","journal-title":"Journal of Personality Assessment"},{"issue":"8","key":"pone.0342307.ref046","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinepi.2010.03.004","article-title":"CONSORT 2010 Explanation and Elaboration: Updated guidelines for reporting parallel group randomised trials","volume":"63","author":"D Moher","year":"2010","journal-title":"J Clin Epidemiol"},{"key":"pone.0342307.ref047","doi-asserted-by":"crossref","unstructured":"Fairburn CG, Beglin SJ. Eating Disorder Examination Questionnaire (EDE-Q). 1994;16(4):363\u201370.","DOI":"10.1002\/1098-108X(199412)16:4<363::AID-EAT2260160405>3.0.CO;2-#"},{"key":"pone.0342307.ref048","doi-asserted-by":"crossref","first-page":"104808","DOI":"10.1016\/j.neubiorev.2022.104808","article-title":"Gender differences in interoceptive accuracy and emotional ability: An explanation for incompatible findings","volume":"141","author":"F Prentice","year":"2022","journal-title":"Neurosci Biobehav Rev"},{"issue":"3","key":"pone.0342307.ref049","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0150205","article-title":"Defining feasibility and pilot studies in preparation for randomised controlled trials: development of a conceptual framework","volume":"11","author":"SM Eldridge","year":"2016","journal-title":"PLoS One"},{"issue":"1","key":"pone.0342307.ref050","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/s12913-017-2031-8","article-title":"Acceptability of healthcare interventions: an overview of reviews and development of a theoretical framework","volume":"17","author":"M Sekhon","year":"2017","journal-title":"BMC Health Serv Res"},{"key":"pone.0342307.ref051","volume-title":"R: A language and environment for statistical computing","author":"R Core Team","year":"2021"},{"key":"pone.0342307.ref052","doi-asserted-by":"crossref","first-page":"108239","DOI":"10.1016\/j.biopsycho.2021.108239","article-title":"The heart rate discrimination task: A psychophysical method to estimate the accuracy and precision of interoceptive beliefs","volume":"168","author":"N Legrand","year":"2022","journal-title":"Biol Psychol"},{"key":"pone.0342307.ref053","doi-asserted-by":"crossref","first-page":"104711","DOI":"10.1016\/j.neubiorev.2022.104711","article-title":"Effects of voluntary slow breathing on heart rate and heart rate variability: a systematic review and a meta-analysis","volume":"138","author":"S Laborde","year":"2022","journal-title":"Neurosci Biobehav Rev"},{"issue":"2","key":"pone.0342307.ref054","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1037\/0033-3204.45.2.247","article-title":"Early withdrawal from mental health treatment: implications for psychotherapy practice","volume":"45","author":"MS Barrett","year":"2008","journal-title":"Psychotherapy (Chic)"},{"issue":"3","key":"pone.0342307.ref055","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1080\/24750158.2018.1500436","article-title":"Challenges of recruitment and retention of university students as research participants: lessons learned from a pilot study","volume":"67","author":"P Khatamian Far","year":"2018","journal-title":"J Australian Library Information Association"},{"key":"pone.0342307.ref056","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/1471-2288-14-118","article-title":"Handling missing data in RCTs; a review of the top medical journals","volume":"14","author":"ML Bell","year":"2014","journal-title":"BMC Med Res Methodol"},{"key":"pone.0342307.ref057","doi-asserted-by":"crossref","first-page":"107602","DOI":"10.1016\/j.cct.2024.107602","article-title":"Addressing missing outcome data in randomised controlled trials: A methodological scoping review","volume":"143","author":"E Medcalf","year":"2024","journal-title":"Contemp Clin Trials"},{"key":"pone.0342307.ref058","doi-asserted-by":"crossref","first-page":"100235","DOI":"10.1016\/j.ynstr.2020.100235","article-title":"A systematic review of the Trier Social Stress Test methodology: Issues in promoting study comparison and replicable research","volume":"13","author":"NF Narvaez Linares","year":"2020","journal-title":"Neurobiol Stress"},{"key":"pone.0342307.ref059","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.neubiorev.2014.09.011","article-title":"Experimental public speaking: contributions to the understanding of the serotonergic modulation of fear","author":"C Garcia-Leal","year":"2014","journal-title":"Neurosci Biobehav Rev"},{"issue":"9","key":"pone.0342307.ref060","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1097\/PSY.0000000000000002","article-title":"Classification criteria for distinguishing cortisol responders from nonresponders to psychosocial stress: evaluation of salivary cortisol pulse detection in panel designs","volume":"75","author":"R Miller","year":"2013","journal-title":"Psychosom Med"},{"issue":"1","key":"pone.0342307.ref061","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1136\/practneurol-2015-001241","article-title":"Functional neurological disorders: the neurological assessment as treatment","volume":"16","author":"J Stone","year":"2016","journal-title":"Pract Neurol"},{"issue":"2","key":"pone.0342307.ref062","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1080\/08870440512331317670","article-title":"Bridging the intention\u2013behaviour gap: Planning, self-efficacy, and action control in the adoption and maintenance of physical exercise","volume":"20","author":"FF Sniehotta","year":"2005","journal-title":"Psychology & Health"},{"key":"pone.0342307.ref063","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.appet.2017.12.016","article-title":"How to bridge the intention-behavior gap in food parenting: Automatic constructs and underlying techniques","volume":"123","author":"JK Larsen","year":"2018","journal-title":"Appetite"},{"issue":"1","key":"pone.0342307.ref064","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1123\/jpah.2019-0033","article-title":"The relationship of self-efficacy and explicit and implicit associations on the intention-behavior gap","volume":"18","author":"A Divine","year":"2021","journal-title":"J Phys Act Health"},{"key":"pone.0342307.ref065","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.chb.2014.07.049","article-title":"Evaluating mobile apps for breathing training: The effectiveness of visualization","volume":"40","author":"L Chittaro","year":"2014","journal-title":"Computers in Human Behavior"},{"issue":"9","key":"pone.0342307.ref066","doi-asserted-by":"crossref","DOI":"10.2196\/13703","article-title":"A Biofeedback App to Instruct Abdominal Breathing (Breathing-Mentor): Pilot Experiment","volume":"7","author":"CA Faust-Christmann","year":"2019","journal-title":"JMIR Mhealth Uhealth"},{"key":"pone.0342307.ref067","doi-asserted-by":"crossref","unstructured":"Theodore G, Huang J-Y, Cheng L-P, Hung Y-P. Breathm: A Calm Device with Personalized Slow Breathing Guidance. In: Extended Abstracts of the CHI Conference on Human Factors in Computing Systems. 2024;1\u20135. https:\/\/doi.org\/10.1145\/3613905.3650943","DOI":"10.1145\/3613905.3650943"}],"container-title":["PLOS One"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0342307","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T18:34:05Z","timestamp":1770230045000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0342307"}},"subtitle":[],"editor":[{"given":"Federica","family":"Scarpina","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,2,4]]},"references-count":67,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,2,4]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0342307","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,4]]}}}