{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T19:24:13Z","timestamp":1772479453900,"version":"3.50.1"},"reference-count":59,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/publicdomain\/zero\/1.0\/"}],"funder":[{"DOI":"10.13039\/100007917","name":"Agricultural Research Service","doi-asserted-by":"publisher","award":["5030-32000-237-00-D"],"award-info":[{"award-number":["5030-32000-237-00-D"]}],"id":[{"id":"10.13039\/100007917","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007917","name":"Agricultural Research Service","doi-asserted-by":"publisher","award":["0201-88888-003-000D"],"award-info":[{"award-number":["0201-88888-003-000D"]}],"id":[{"id":"10.13039\/100007917","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>\n                    <jats:italic>Bordetella bronchiseptica<\/jats:italic>\n                    is a highly contagious veterinary bacterial respiratory pathogen with a broad host range that can cause a variety of clinical disease outcomes ranging from asymptomatic carriage to severe pneumonia.\n                    <jats:italic>B. bronchiseptica<\/jats:italic>\n                    fimbriae mediate attachment to respiratory epithelium and are considered to serve as potential protective antigens. Several comparative genomic studies involving\n                    <jats:italic>B. bronchiseptica<\/jats:italic>\n                    strains have demonstrated an overall low level of genomic variability. The region located within the\n                    <jats:italic>fimX<\/jats:italic>\n                    locus is one of the few regions in which genomic variability has been reported. The goal of this study was to comprehensively evaluate the genomic variability harbored within the\n                    <jats:italic>fimX<\/jats:italic>\n                    locus among\n                    <jats:italic>B. bronchiseptica<\/jats:italic>\n                    strains. Our analysis revealed that the genetic variability identified within the\n                    <jats:italic>fimX<\/jats:italic>\n                    locus included both the number of genes harbored, as well as the type of predicted fimbrial subunit gene types contained within the\n                    <jats:italic>fimX<\/jats:italic>\n                    locus. A total of six different fimbrial subunit gene types were identified among the\n                    <jats:italic>B. bronchiseptica<\/jats:italic>\n                    genome assemblies analyzed in this study. Comparative analysis data also suggests that the diversity among the fimbrial subunit genes located within the\n                    <jats:italic>fimX<\/jats:italic>\n                    locus was likely generated by homologous recombination.\n                  <\/jats:p>","DOI":"10.1371\/journal.pone.0342754","type":"journal-article","created":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T18:22:46Z","timestamp":1772475766000},"page":"e0342754","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative analysis of the diversity within the B. bronchiseptica fimX locus"],"prefix":"10.1371","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1471-0359","authenticated-orcid":true,"given":"Tracy L.","family":"Nicholson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8247-4712","authenticated-orcid":true,"given":"Sarah M.","family":"Shore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2026,3,2]]},"reference":[{"issue":"2","key":"pone.0342754.ref001","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1128\/CMR.18.2.326-382.2005","article-title":"Molecular pathogenesis, epidemiology, and clinical manifestations of respiratory infections due to Bordetella pertussis and other Bordetella subspecies","volume":"18","author":"S Mattoo","year":"2005","journal-title":"Clin Microbiol Rev"},{"key":"pone.0342754.ref002","first-page":"767","article-title":"Bordetellosis. 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