{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T19:18:07Z","timestamp":1771615087511,"version":"3.50.1"},"reference-count":42,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:00:00Z","timestamp":1771545600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aim of this study is to explore the moderating role of different affective temperaments in the relationship between Borderline Personality traits (BPT) and Mood Instability (MI) among a sample of Lebanese adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross-sectional study was conducted in Lebanon in May 2025. An online survey that included the Mood Instability Questionnaire \u2013 Trait Short Form (MIQ-T-SF), Temperament Evaluation of Memphis, Pisa, Paris, and San Diego \u2013 Modified (TEMPS-M), and McLean Screening Questionnaire for Borderline Personality Disorder (MSI-BPD) was used to collect data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 872 participants completed the survey, with 66.9% being females and a mean age of 26.97 years. The interactions between borderline personality traits and depressive\/cyclothymic\/hyperthymic\/anxious temperaments were associated with increased mood instability. Higher borderline personality scores were associated with lower (Beta\u2009=\u2009\u22120.50; p\u2009&lt;\u20090.001) and higher (Beta\u2009=\u20090.39; p\u2009=\u20090.016) mood instability scores at low and high levels of depressive temperament respectively. Higher borderline personality scores were associated with lower mood instability scores (Beta\u2009=\u2009\u22120.51; p\u2009&lt;\u20090.001) at low levels of cyclothymic temperament respectively. At moderate (Beta\u2009=\u20090.67; p\u2009&lt;\u20090.001) and high (Beta\u2009=\u20091.41; p\u2009&lt;\u20090.001) levels of hyperthymic temperament, higher borderline personality scores were associated with higher mood instability scores. Higher borderline personality scores were associated with lower (Beta\u2009=\u2009\u22120.37; p\u2009=\u20090.008) and higher (Beta\u2009=\u20090.40; p\u2009=\u20090.012) mood instability scores at low and high levels of anxious temperament respectively. The irritable temperament did not moderate the relationship between borderline personality traits and mood instability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study emphasizes the nature of the relationship between affective temperaments, BPT, and MI. These findings are especially important for the Lebanese population, threatened by a rising psychopathology prevalence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0343047","type":"journal-article","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T18:25:00Z","timestamp":1771611900000},"page":"e0343047","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Moderating effect of temperaments between borderline personality traits and mood instability among a sample of Lebanese adults"],"prefix":"10.1371","volume":"21","author":[{"given":"Emmanuelle","family":"Awad","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Malaeb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fouad","family":"Sakr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariam","family":"Dabbous","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6918-5689","authenticated-orcid":true,"given":"Souheil","family":"Hallit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feten","family":"Fekih-Romdhane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0735-4704","authenticated-orcid":true,"given":"Sahar","family":"Obeid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2026,2,20]]},"reference":[{"key":"pone.0343047.ref001","first-page":"1224","volume-title":"Mood instability: what it is, why it matters, and what to do about it","author":"MA Fristad","year":"2022"},{"issue":"6","key":"pone.0343047.ref002","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1002\/ajmg.b.32907","article-title":"The shared genetic basis of mood instability and psychiatric disorders: a cross-trait genome-wide association analysis","volume":"189","author":"G Hindley","year":"2022","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"issue":"5","key":"pone.0343047.ref003","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2014-007504","article-title":"Mood instability is a common feature of mental health disorders and is associated with poor clinical outcomes","volume":"5","author":"R Patel","year":"2015","journal-title":"BMJ Open"},{"issue":"4","key":"pone.0343047.ref004","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1192\/bjp.bp.114.158543","article-title":"Mood instability: significance, definition and measurement","volume":"207","author":"MR Broome","year":"2015","journal-title":"Br J Psychiatry"},{"issue":"8","key":"pone.0343047.ref005","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1001\/jama.2023.0589","article-title":"Borderline personality disorder: a review","volume":"329","author":"F Leichsenring","year":"2023","journal-title":"JAMA"},{"key":"pone.0343047.ref006","doi-asserted-by":"crossref","first-page":"18029","DOI":"10.1038\/nrdp.2018.29","article-title":"Borderline personality disorder","volume":"4","author":"JG Gunderson","year":"2018","journal-title":"Nat Rev Dis Primers"},{"issue":"10","key":"pone.0343047.ref007","first-page":"1","article-title":"Comparison of impulsivity, emotional instability, decision making and risky behaviors in patients with bipolar disorder and borderline personality disorder","volume":"3","author":"A Abolalaei","year":"2022","journal-title":"J Res Psychopathol"},{"issue":"1","key":"pone.0343047.ref008","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1590\/2237-6089-2018-0010","article-title":"Dependency, mood instability, and inconsequence traits for discriminating borderline personality disorder","volume":"41","author":"F Carvalho L de","year":"2019","journal-title":"Trends Psychiatry Psychother"},{"issue":"1","key":"pone.0343047.ref009","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s12991-023-00439-0","article-title":"The role of emotional instability in borderline personality disorder: a systematic review","volume":"22","author":"G D\u2019Aurizio","year":"2023","journal-title":"Ann Gen Psychiatry"},{"key":"pone.0343047.ref010","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1017\/9781108776660.017","article-title":"Nobody? 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