{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T19:12:46Z","timestamp":1772565166903,"version":"3.50.1"},"reference-count":31,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T00:00:00Z","timestamp":1772496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001322","name":"South African Medical Research Council","doi-asserted-by":"publisher","award":["M34"],"award-info":[{"award-number":["M34"]}],"id":[{"id":"10.13039\/501100001322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>Drug-resistant tuberculosis (DR-TB) is a global health problem that presents multifaceted challenges to people living with the disease. These challenges lead to sub-optimal adherence in some DR-TB patients who are then not cured of their TB. Besides the challenges associated with taking treatment, many patients with DR-TB also have to contend with psychosocial and socioeconomic challenges. The objective of this study was to develop a psychosocial and socioeconomic intervention for people with DR-TB in Johannesburg, South Africa, and evaluate if they find it acceptable. Guided by the Behaviour Change Wheel (BCW) and Perceptions and Practicalities Approach (PaPA) frameworks, and utilising a participatory research approach, We developed a support package with input from a qualitative needs assessment with DR-TB patients (n\u2009=\u200916) and family members (n\u2009=\u20098) and input from various stakeholders (n\u2009=\u200918), (health managers, clinicians and officials from social security departments). The support package was then evaluated for acceptability by patients who had successfully completed DR-TB treatment (n\u2009=\u200913) and their families (n\u2009=\u20096), using an exploratory qualitative method. Both successfully treated DR-TB patients and their family members found the intervention to be acceptable and believed it will reduce the barriers to retention in care that they faced during their treatment journey.<\/jats:p>","DOI":"10.1371\/journal.pone.0343154","type":"journal-article","created":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T18:25:25Z","timestamp":1772562325000},"page":"e0343154","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Designing and evaluating the acceptability of a psychosocial and socioeconomic support package for people with drug-resistant tuberculosis in Johannesburg, South Africa"],"prefix":"10.1371","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1540-6033","authenticated-orcid":true,"given":"Ndiviwe","family":"Mphothulo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marian","family":"Loveday","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2026,3,3]]},"reference":[{"key":"pone.0343154.ref001","unstructured":"Global tuberculosis report 2024. 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