{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T13:48:59Z","timestamp":1774878539979,"version":"3.50.1"},"reference-count":131,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100018694","name":"HORIZON EUROPE Marie Sklodowska-Curie Actions","doi-asserted-by":"publisher","award":["813546"],"award-info":[{"award-number":["813546"]}],"id":[{"id":"10.13039\/100018694","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Attention deficits are common among school-aged children and affect their social, academic, and family lives, making it necessary to receive adequate support and intervention strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed (a) to evaluate whether a multilevel intervention program \u2013combining parent training, child training based on a cognitive-behavioral approach, and iVR-based cognitive training\u2014could improve attention, executive functions, and psychosocial adjustment in children with attention deficits, and (b) to examine whether outcomes differed according to the sequence in which the intervention components were delivered. This pilot study was conducted as a precursor to a larger study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Sixteen families were randomly assigned to two groups following a sequential intervention design, with each group receiving the same components in a different order. Hence, families in the PC group received parent training first, followed by child training, while families in the CP group began with child training, followed by parent training (Clinical Trials Registry NCT05391698).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>After participating in the intervention program, children demonstrated enhanced attentional and inhibitory control and sustained attention, as measured by fewer omission and commission errors, faster hit reaction time, and improved executive score. They also exhibited gains in working memory, processing speed, and planning and programming abilities and reported reduced behavioral problems. Emotional competence improved significantly only for the PC group. A significant time X group interaction was found for school competence, with the PC group showing a more pronounced improvement over time than the CP group. In contrast, no significant changes were observed in alerting and orienting scores, reaction time variability, social competence or self-perception skills.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec005\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The findings have important implications, suggesting that multilevel intervention programs \u2013 particularly those integrating iVR-based cognitive training \u2013 may positively impact specific cognitive and psychosocial outcomes in children with attention deficits. As a pilot study, these results provide preliminary evidence and methodological insights to guide the design and rationale of future larger-scale studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0343364","type":"journal-article","created":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T18:27:31Z","timestamp":1772216851000},"page":"e0343364","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Child training in the Child ViReal Support Program: Combining iVR-based cognitive training and CBT techniques in a pilot study"],"prefix":"10.1371","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8515-1438","authenticated-orcid":true,"given":"Iouliani","family":"Pachiti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fotios S.","family":"Milienos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5541-568X","authenticated-orcid":true,"given":"Timothy C.","family":"Papadopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3350-3216","authenticated-orcid":true,"given":"Panagiota","family":"Dimitropoulou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2026,2,27]]},"reference":[{"issue":"10","key":"pone.0343364.ref001","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1038\/nrn4025","article-title":"The attentive brain: insights from developmental cognitive neuroscience","volume":"16","author":"D Amso","year":"2015","journal-title":"Nat Rev 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Han","year":"2021","journal-title":"Mindfulness"},{"key":"pone.0343364.ref034","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.ctcp.2017.05.015","article-title":"Mindfulness programming for parents and teachers of children with ADHD","volume":"28","author":"CJ Miller","year":"2017","journal-title":"Complement Ther Clin Pract"},{"issue":"2","key":"pone.0343364.ref035","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1080\/15374416.2017.1390757","article-title":"Evidence-Based Psychosocial Treatments for Children and Adolescents With Attention Deficit\/Hyperactivity Disorder","volume":"47","author":"SW Evans","year":"2018","journal-title":"J Clin Child Adolesc Psychol"},{"key":"pone.0343364.ref036","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jpsychires.2019.10.007","article-title":"Non-pharmacological interventions for cognitive difficulties in ADHD: A systematic review and meta-analysis","volume":"120","author":"B Lambez","year":"2020","journal-title":"J Psychiatr Res"},{"key":"pone.0343364.ref037","doi-asserted-by":"crossref","first-page":"859249","DOI":"10.3389\/fpsyt.2022.859249","article-title":"Beneficial effects of behavioral parent training on inhibitory control in children with attention-deficit\/hyperactivity disorder: A small-scale randomized controlled trial","volume":"13","author":"A Yao","year":"2022","journal-title":"Front Psychiatry"},{"issue":"3","key":"pone.0343364.ref038","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.jaac.2014.12.010","article-title":"Cognitive training for attention-deficit\/hyperactivity disorder: meta-analysis of clinical and neuropsychological outcomes from randomized controlled trials","volume":"54","author":"S Cortese","year":"2015","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"pone.0343364.ref039","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.3389\/fpsyg.2019.02983","article-title":"Effectiveness of 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Bouchard","year":"2019"},{"issue":"5","key":"pone.0343364.ref045","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1111\/jcpp.13400","article-title":"Annual Research Review: Immersive virtual reality and digital applied gaming interventions for the treatment of mental health problems in children and young people: the need for rigorous treatment development and clinical evaluation","volume":"62","author":"B Halldorsson","year":"2021","journal-title":"J Child Psychol Psychiatry"},{"issue":"8","key":"pone.0343364.ref046","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1162\/jocn_a_01560","article-title":"Enhanced attention using head-mounted virtual reality","volume":"32","author":"G Li","year":"2020","journal-title":"Journal of Cognitive Neuroscience"},{"key":"pone.0343364.ref047","first-page":"541","volume-title":"Is Immersive Virtual Reality in K-12 Education Ready for Primetime? 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Bioulac","year":"2020","journal-title":"J Atten Disord"},{"issue":"2","key":"pone.0343364.ref052","first-page":"70","article-title":"Effectiveness of Virtual Reality-Based Interventions for Children and Adolescents with ADHD: A Systematic Review and Meta-Analysis","volume":"8","author":"D Romero-Ayuso","year":"2021","journal-title":"Children (Basel)"},{"issue":"4","key":"pone.0343364.ref053","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3390\/systems10040104","article-title":"Effectiveness of Virtual Reality on Attention Training for Elementary School Students","volume":"10","author":"W Tarng","year":"2022","journal-title":"Systems"},{"key":"pone.0343364.ref054","first-page":"1","article-title":"Immersive virtual reality for improving cognitive deficits in children with ADHD: a systematic review and meta-analysis","author":"N Corrigan","year":"2023","journal-title":"Virtual 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Sprich","year":"2016","journal-title":"J Child Psychol Psychiatry"},{"issue":"4","key":"pone.0343364.ref063","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1080\/09297049.2017.1282450","article-title":"Sequenced neurocognitive and behavioral parent training for the treatment of ADHD in school-age children","volume":"24","author":"A Chacko","year":"2018","journal-title":"Child Neuropsychol"},{"key":"pone.0343364.ref064","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2015.00167","article-title":"Use of Cognitive Behavioral Therapy and Token Economy to Alleviate Dysfunctional Behavior in Children with Attention-Deficit Hyperactivity Disorder","volume":"6","author":"LF Coelho","year":"2015","journal-title":"Front Psychiatry"},{"key":"pone.0343364.ref065","first-page":"37","article-title":"Attention deficit hyperactivity disorder.","volume-title":"Handbook of Clinical Neurology [Internet]","author":"KM Antshel","year":"2020"},{"issue":"1","key":"pone.0343364.ref066","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1177\/1550059414563746","article-title":"Enhancing cognitive function using perceptual-cognitive training","volume":"47","author":"B Parsons","year":"2016","journal-title":"Clin EEG Neurosci"},{"key":"pone.0343364.ref067","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.lindif.2015.11.012","article-title":"Does attention training work? 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Rehabilitation of Attention Deficits","volume":"3","author":"AA Rizzo","year":"2000","journal-title":"Cyberpsychol Behav"},{"issue":"1","key":"pone.0343364.ref075","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1017\/S1092852900024196","article-title":"A virtual reality scenario for all seasons: the virtual classroom","volume":"11","author":"AA Rizzo","year":"2006","journal-title":"CNS Spectr"},{"key":"pone.0343364.ref076","volume-title":"Parent management training: Treatment for oppositional, aggressive, and antisocial behavior in children and adolescents","author":"AE Kazdin","year":"2005"},{"key":"pone.0343364.ref077","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/B978-0-12-410388-7.00011-7","article-title":"Cognitive Constructs and Individual Differences Underlying ADHD and Dyslexia: A cognitive mosaic approach.","volume-title":"Cognition, Intelligence, and Achievement: A tribute to J P Das [Internet]","author":"JR Kirby","year":"2015"},{"key":"pone.0343364.ref078","first-page":"1131","article-title":"Executive function training for children with ADHD.","volume-title":"Attention-Deficit Hyperactivity Disorder: A handbook for diagnosis and treatment","author":"MD Rapport","year":"2015","edition":"4"},{"key":"pone.0343364.ref079","author":"P Dimitropoulou","year":"2022"},{"issue":"8","key":"pone.0343364.ref080","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/j.neuropsychologia.2003.12.012","article-title":"Development of attentional networks in childhood","volume":"42","author":"MR Rueda","year":"2004","journal-title":"Neuropsychologia"},{"issue":"3","key":"pone.0343364.ref081","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1162\/089892902317361886","article-title":"Testing the efficiency and independence of attentional networks","volume":"14","author":"J Fan","year":"2002","journal-title":"J Cogn 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Psychol"},{"issue":"1","key":"pone.0343364.ref085","doi-asserted-by":"crossref","first-page":"195","DOI":"10.3758\/s13428-018-01193-y","article-title":"PsychoPy2: Experiments in behavior made easy","volume":"51","author":"J Peirce","year":"2019","journal-title":"Behav Res Methods"},{"issue":"12","key":"pone.0343364.ref086","doi-asserted-by":"crossref","first-page":"167","DOI":"10.3390\/brainsci7120167","article-title":"EEG Dynamics of a Go\/Nogo Task in Children with ADHD","volume":"7","author":"S Baijot","year":"2017","journal-title":"Brain Sci"},{"issue":"2","key":"pone.0343364.ref087","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1037\/a0027205","article-title":"Evaluating vigilance deficits in ADHD: a meta-analysis of CPT performance","volume":"121","author":"CL Huang-Pollock","year":"2012","journal-title":"J Abnorm Psychol"},{"key":"pone.0343364.ref088","volume-title":"Conners\u2019 Continuous Performance Test 3rd Edition [Internet]","author":"CK Conners","year":"2014"},{"issue":"1","key":"pone.0343364.ref089","doi-asserted-by":"crossref","DOI":"10.1111\/desc.13252","article-title":"Intra-individual variability in task performance after cognitive training is associated with long-term outcomes in children","volume":"26","author":"A Cubillo","year":"2023","journal-title":"Dev Sci"},{"key":"pone.0343364.ref090","first-page":"1","article-title":"Relationship between reaction time variability on go\/no go tasks and neuropsychological functioning in younger and older adults","author":"N Kimura","year":"2024","journal-title":"J Clin Exp Neuropsychol"},{"issue":"6","key":"pone.0343364.ref091","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1111\/jcpp.12217","article-title":"Annual research review: Reaction time variability in ADHD and autism spectrum disorders: measurement and mechanisms of a proposed trans-diagnostic phenotype","volume":"55","author":"SL Karalunas","year":"2014","journal-title":"J Child Psychol Psychiatry"},{"key":"pone.0343364.ref092","volume-title":"Test of Executive Function for Elementary School Students: Description","author":"P Simos","year":"2007"},{"key":"pone.0343364.ref093","volume-title":"Test of Executive Function for Elementary School Students: Examiner\u2019s Guide","author":"P Simos","year":"2007"},{"key":"pone.0343364.ref094","volume-title":"NEPSY: A Developmental Neuropsychological Assessment Manual","author":"M Korkman","year":"1998"},{"issue":"7","key":"pone.0343364.ref095","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1007\/s10072-017-2957-y","article-title":"The Tower of London (ToL) in Italy: standardization of the ToL test in an Italian population","volume":"38","author":"M Boccia","year":"2017","journal-title":"Neurol Sci"},{"issue":"2","key":"pone.0343364.ref096","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1080\/09297049.2019.1642317","article-title":"Psychometric analyses of the Tower of London planning task reveal high reliability and feasibility in typically developing children and child patients with ASD and ADHD","volume":"26","author":"JM Unterrainer","year":"2020","journal-title":"Child Neuropsychol"},{"issue":"3","key":"pone.0343364.ref097","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1093\/arclin\/acw007","article-title":"Stability in Test-Usage Practices of Clinical Neuropsychologists in the United States and Canada Over a 10-Year Period: A Follow-Up Survey of INS and NAN Members","volume":"31","author":"LA Rabin","year":"2016","journal-title":"Arch Clin Neuropsychol"},{"key":"pone.0343364.ref098","article-title":"Tools for detecting attention\/concentration and executive function disorders in elementary school students: Examination of concurrent validity","volume-title":"Special education as a starting point for progress in science and practice","author":"A Mouzaki","year":"2011"},{"key":"pone.0343364.ref099","volume-title":"Test of psychosocial adjustment: Description [in Greek]","author":"C Hatzichristou","year":"2008"},{"key":"pone.0343364.ref100","volume-title":"Test of psychosocial adjustment: examiner\u2019s manual","author":"C Hatzichristou","year":"2008"},{"issue":"3","key":"pone.0343364.ref101","first-page":"30","article-title":"The effects of quarantine (Covid-19) on psychosocial adjustment of 5th and 6th graders","volume":"2021","author":"F Antoniou","year":"2021","journal-title":"Educ Sci"},{"key":"pone.0343364.ref102","volume-title":"WISC-V GR (Wechsler intelligence scale for children \u2013 5th edition)","year":"2017"},{"issue":"3","key":"pone.0343364.ref103","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1177\/135910457000100301","article-title":"Back-Translation for Cross-Cultural Research","volume":"1","author":"RW Brislin","year":"1970","journal-title":"J Cross-Cult Psychol"},{"key":"pone.0343364.ref104","first-page":"137","volume-title":"The wording and translation of research instruments. 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Brooke","year":"1996"},{"issue":"2","key":"pone.0343364.ref114","first-page":"29","article-title":"SUS: A retrospective","volume":"8","author":"J Brooke","year":"2013","journal-title":"J Usability Stud"},{"key":"pone.0343364.ref115","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780198524847.001.0001","volume-title":"Analysis of Longitudinal Data","author":"P Diggle","year":"2002","edition":"2"},{"key":"pone.0343364.ref116","volume-title":"IBM SPSS Statistics for Windows","year":"2023"},{"key":"pone.0343364.ref117","volume-title":"R: A language and environment for statistical computing","author":"R Core Team","year":"2024"},{"key":"pone.0343364.ref118","first-page":"267","article-title":"Information theory and an extension of maximum likelihood principle.","volume-title":"Proceedings of 2nd International Symposium on Information Theory [Internet]","author":"H. Akaike","year":"1973"},{"key":"pone.0343364.ref119","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/978-1-4612-1694-0_15","article-title":"Information Theory and an Extension of the Maximum Likelihood Principle.","author":"H. Akaike","year":"1998","journal-title":"Selected Papers of Hirotugu Akaike [Internet]"},{"issue":"2","key":"pone.0343364.ref120","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1111\/j.2517-6161.1979.tb01084.x","article-title":"Comments on Model Selection Criteria of Akaike and Schwarz","volume":"41","author":"M Stone","year":"1979","journal-title":"Journal of the Royal Statistical Society Series B: Statistical Methodology"},{"key":"pone.0343364.ref121","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-4419-0318-1_1","article-title":"Linear Mixed-Effects Models: Basic Concepts and Examples.","volume-title":"Mixed-Effects Models in S and S-PLUS [Internet]","author":"JC Pinheiro","year":"2000"},{"key":"pone.0343364.ref122","doi-asserted-by":"crossref","first-page":"45996","DOI":"10.1109\/ACCESS.2020.2977688","article-title":"Eye-Contact Game Using Mixed Reality for the Treatment of Children With Attention Deficit Hyperactivity Disorder","volume":"8","author":"S Kim","year":"2020","journal-title":"IEEE Access"},{"issue":"3","key":"pone.0343364.ref123","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s12402-011-0059-x","article-title":"Training of attention functions in children with attention deficit hyperactivity disorder","volume":"3","author":"O Tucha","year":"2011","journal-title":"Atten Defic Hyperact Disord"},{"issue":"12","key":"pone.0343364.ref124","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0261981","article-title":"Enhancing neural markers of attention in children with ADHD using a digital therapeutic","volume":"16","author":"CL Gallen","year":"2021","journal-title":"PLoS One"},{"issue":"3","key":"pone.0343364.ref125","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.3758\/s13428-021-01668-5","article-title":"Assessing the three attentional networks in children from three to six years: A child-friendly version of the Attentional Network Test for Interaction","volume":"54","author":"M Casagrande","year":"2022","journal-title":"Behav Res Methods"},{"issue":"10","key":"pone.0343364.ref126","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1037\/a0037469","article-title":"Development of attention networks and their interactions in childhood","volume":"50","author":"JP Pozuelos","year":"2014","journal-title":"Dev Psychol"},{"key":"pone.0343364.ref127","doi-asserted-by":"crossref","first-page":"103692","DOI":"10.1016\/j.ajp.2023.103692","article-title":"Efficacy of non-pharmacological interventions on executive functions in children and adolescents with ADHD: A systematic review and meta-analysis","volume":"87","author":"H Qiu","year":"2023","journal-title":"Asian J Psychiatr"},{"issue":"13","key":"pone.0343364.ref128","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1177\/10870547231187164","article-title":"Effect of Cognitive Training Programs Based on Computer Systems on Executive Functions in Children With ADHD: A Systematic 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