{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T01:33:03Z","timestamp":1791595983385,"version":"4.3.4"},"reference-count":76,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T00:00:00Z","timestamp":1772668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008638","name":"Environment and Climate Change Canada","doi-asserted-by":"publisher","award":["Canada Nature Fund - no specific grant number"],"award-info":[{"award-number":["Canada Nature Fund - no specific grant number"]}],"id":[{"id":"10.13039\/501100008638","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>\n                    Free-ranging wild ungulates are integral to the health and well-being of Canadian socioecological systems, contributing various One Health benefits (e.g., nutrient cycling, sustainable food resources) to the people and other animals that coexist with them. In North America, ungulates face a range of threats to their population health. To address knowledge gaps surrounding the health of Canadian ungulates, we conducted a retrospective analysis of 20 years of ungulate morbidity and mortality data collected through passive disease surveillance conducted by the Canadian Wildlife Health Cooperative (CWHC) and through submissions from collaborative partners. In total, 2525 cases across 12 species were assigned a category of diagnosis (COD) by a CWHC veterinary pathologist. Infectious\/ inflammatory\/ transmissible CODs accounted for 53.0% of all cases, with two diagnoses made most frequently: chronic wasting disease (CWD) and\n                    <jats:italic>Parelaphostrongylus tenuis<\/jats:italic>\n                    (\n                    <jats:italic>P. tenuis<\/jats:italic>\n                    ) infection. We identified a significant increase in the proportion of cervid cases diagnosed with CWD in Saskatchewan that was consistent across species, with the odds of an individual cervid in Saskatchewan being CWD positive increasing by 22% per year. We also detected a significant increase in the proportion of moose (\n                    <jats:italic>Alces americanus<\/jats:italic>\n                    ) cases diagnosed with\n                    <jats:italic>P. tenuis<\/jats:italic>\n                    , and this trend was consistent across endemic regions in Canada. Emerging diseases were also detected for the first time through our surveillance approach (e.g., the first Ontario cases of epizootic hemorrhagic disease virus, detected in white-tailed deer (\n                    <jats:italic>Odocoileus virginianus<\/jats:italic>\n                    )). Trauma (15.3%) and emaciation (8.9%) were the most frequently assigned non-infectious CODs. We highlight potential disease threats to SAR that may emerge secondary to changing distributions of sympatric ungulate species and the pathogens they carry (e.g., CWD positive deer\/elk within known caribou ranges in Saskatchewan). Our results highlight the strengths of passive disease surveillance, as well as the need for an integrated, holistic wildlife surveillance approach in Canada.\n                  <\/jats:p>","DOI":"10.1371\/journal.pone.0343520","type":"journal-article","created":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T18:31:44Z","timestamp":1772735504000},"page":"e0343520","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Twenty years of ungulate disease surveillance by the Canadian Wildlife Health Cooperative (2003\u20132022)"],"prefix":"10.1371","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8655-129X","authenticated-orcid":true,"given":"Kerry","family":"Schutten","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard","family":"Shirose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Stevens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dayna","family":"Goldsmith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Owen","family":"Slater","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie 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Timmermann","year":"2017","journal-title":"Alces"},{"issue":"9","key":"pone.0343520.ref017","doi-asserted-by":"crossref","DOI":"10.1111\/gcb.17498","article-title":"The influence of habitat alteration on density of invading white-tailed deer should not be discounted","volume":"30","author":"A Barnas","year":"2024","journal-title":"Glob Chang Biol"},{"issue":"2","key":"pone.0343520.ref018","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1002\/jwmg.21979","article-title":"Evaluating the Mechanisms of Landscape Change on White\u2010Tailed Deer Populations","volume":"85","author":"M Laurent","year":"2020","journal-title":"J Wildl Manag"},{"key":"pone.0343520.ref019","first-page":"15","article-title":"Winter habitat selection of moose in Maine and ruminations on the impact of changing weather conditions","volume":"59","author":"A 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susceptibility","volume":"29","author":"MI Arifin","year":"2020","journal-title":"Mol Ecol"},{"issue":"3","key":"pone.0343520.ref025","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1111\/j.1365-2656.2005.00953.x","article-title":"The effect of bovine tuberculosis and brucellosis on reproduction and survival of wood bison in Wood Buffalo National Park","volume":"74","author":"DO Joly","year":"2005","journal-title":"Journal of Animal Ecology"},{"issue":"1","key":"pone.0343520.ref026","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1139\/cjz-2018-0140","article-title":"Mortality assessment of moose (Alces alces) calves during successive years of winter tick (Dermacentor albipictus) epizootics in New Hampshire and Maine (USA)","volume":"97","author":"H Jones","year":"2019","journal-title":"Can J Zool"},{"key":"pone.0343520.ref027","doi-asserted-by":"crossref","first-page":"105512","DOI":"10.1016\/j.prevetmed.2021.105512","article-title":"Spatio-temporal changes in chronic wasting disease risk in wild deer during 14 years of surveillance in Alberta, Canada","volume":"197","author":"P Smolko","year":"2021","journal-title":"Prev Vet Med"},{"issue":"12","key":"pone.0343520.ref028","first-page":"1114","article-title":"Antibiotic treatment of Mycoplasma ovipneumoniae in domestic sheep (Ovis aries): Working at the livestock-wildlife interface in Yukon, Canada","volume":"64","author":"K Magnusson","year":"2023","journal-title":"Can Vet J"},{"issue":"2","key":"pone.0343520.ref029","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1128\/JCM.01931-07","article-title":"Association of Mycoplasma ovipneumoniae infection with population-limiting respiratory disease in free-ranging Rocky Mountain bighorn sheep (Ovis canadensis canadensis)","volume":"46","author":"TE Besser","year":"2008","journal-title":"J Clin Microbiol"},{"key":"pone.0343520.ref030","author":"S Kutz","year":"2005"},{"issue":"1","key":"pone.0343520.ref031","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/s13567-021-00986-y","article-title":"Chronic wasting disease: a cervid prion infection looming to spillover","volume":"52","author":"A Otero","year":"2021","journal-title":"Vet Res"},{"key":"pone.0343520.ref032","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.rvsc.2021.11.003","article-title":"Stepping up from wildlife disease surveillance to integrated wildlife monitoring in Europe","volume":"144","author":"B Cardoso","year":"2022","journal-title":"Res Vet Sci"},{"key":"pone.0343520.ref033","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/978-4-431-77134-0_10","article-title":"Wildlife Disease Surveillance and Monitoring.","author":"M Artois","year":"2009","journal-title":"Management of Disease in Wild Mammals. Tokyo: Springer Japan"},{"issue":"9","key":"pone.0343520.ref034","first-page":"925","article-title":"The Canadian Wildlife Health Cooperative: Addressing wildlife health challenges in the 21st century","volume":"56","author":"C Stephen","year":"2015","journal-title":"Can Vet J"},{"key":"pone.0343520.ref035","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.prevetmed.2011.10.016","article-title":"Targeting the detection of chronic wasting disease using the hunter harvest during early phases of an outbreak in Saskatchewan, Canada","volume":"104","author":"EE Rees","year":"2012","journal-title":"Prev Vet Med"},{"issue":"1","key":"pone.0343520.ref036","doi-asserted-by":"crossref","DOI":"10.18637\/jss.v067.i01","article-title":"Fitting Linear Mixed-Effects Models Usinglme4","volume":"67","author":"D Bates","year":"2015","journal-title":"J Stat Soft"},{"key":"pone.0343520.ref037","author":"F Hartig","year":"2024"},{"issue":"60","key":"pone.0343520.ref038","doi-asserted-by":"crossref","first-page":"3139","DOI":"10.21105\/joss.03139","article-title":"performance: An R Package for Assessment, Comparison and Testing of Statistical Models","volume":"6","author":"D L\u00fcdecke","year":"2021","journal-title":"Journal of Open Source Software"},{"key":"pone.0343520.ref039","year":"2023"},{"key":"pone.0343520.ref040","author":"CFIA","year":"2011"},{"key":"pone.0343520.ref041","author":"Government of Canada","year":"2014"},{"issue":"3","key":"pone.0343520.ref042","doi-asserted-by":"crossref","first-page":"459","DOI":"10.7589\/2013-04-095","article-title":"Descriptive epidemiology of detected anthrax outbreaks in wild wood bison (Bison bison athabascae) in northern Canada, 1962-2008","volume":"50","author":"A Salb","year":"2014","journal-title":"J Wildl Dis"},{"key":"pone.0343520.ref043","author":"Province of British 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Samuel","year":"2007","journal-title":"Alces"},{"issue":"1","key":"pone.0343520.ref049","doi-asserted-by":"crossref","first-page":"157","DOI":"10.7589\/2014-02-037","article-title":"Necropsy findings in 62 opportunistically collected free-ranging moose (Alces alces) from Minnesota, USA (2003-13)","volume":"51","author":"A W\u00fcnschmann","year":"2015","journal-title":"J Wildl Dis"},{"issue":"3","key":"pone.0343520.ref050","doi-asserted-by":"crossref","first-page":"544","DOI":"10.7589\/2018-01-018","article-title":"Health survey of boreal caribou (rangifer tarandus caribou) in northeastern British Columbia, Canada","volume":"55","author":"KJ Bondo","year":"2019","journal-title":"J Wildl Dis"},{"issue":"4","key":"pone.0343520.ref051","doi-asserted-by":"crossref","first-page":"832","DOI":"10.3201\/eid2504.180743","article-title":"Epizootic Hemorrhagic Disease in White-Tailed Deer, Canada","volume":"25","author":"SE Allen","year":"2019","journal-title":"Emerg Infect Dis"},{"key":"pone.0343520.ref052","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.4968","article-title":"Comparative health assessment of urban and non-urban free-ranging mule deer (Odocoileus hemionus) in southeastern British Columbia, Canada","volume":"6","author":"A Mathieu","year":"2018","journal-title":"PeerJ"},{"issue":"4","key":"pone.0343520.ref053","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1177\/1040638718766036","article-title":"Adenoviral hemorrhagic disease in California mule deer, 1990-2014","volume":"30","author":"LW Woods","year":"2018","journal-title":"J Vet Diagn Invest"},{"issue":"6","key":"pone.0343520.ref054","first-page":"560","article-title":"Erysipelothrix rhusiopathiae associated with recent widespread muskox mortalities in the Canadian Arctic","volume":"56","author":"S Kutz","year":"2015","journal-title":"Can Vet 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Cancer"},{"issue":"4","key":"pone.0343520.ref058","doi-asserted-by":"crossref","first-page":"931","DOI":"10.7589\/JWD-D-21-00192","article-title":"Invasive Adenocarcinoma of the Head of a Boreal Woodland Caribou (Rangifer tarandus caribou), Alberta, Canada","volume":"58","author":"OM Slater","year":"2022","journal-title":"J Wildl Dis"},{"issue":"6","key":"pone.0343520.ref059","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0269441","article-title":"Evaluating the use of hair as a non-invasive indicator of trace mineral status in woodland caribou (Rangifer tarandus caribou)","volume":"17","author":"N Jutha","year":"2022","journal-title":"PLoS One"},{"key":"pone.0343520.ref060","article-title":"Surveillance, monitoring and survey of wildlife diseases: a public health and conservation approach","volume":"25","author":"V Guberti","year":"2014","journal-title":"Hystrix, the Italian Journal of 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Lankester","year":"1998","journal-title":"Ran"},{"issue":"1","key":"pone.0343520.ref067","doi-asserted-by":"crossref","first-page":"29","DOI":"10.7589\/2012-05-125","article-title":"Variables associated with Besnoitia tarandi prevalence and cyst density in barren-ground caribou (Rangifer tarandus) populations","volume":"49","author":"J Ducrocq","year":"2013","journal-title":"J Wildl Dis"},{"key":"pone.0343520.ref068","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1007\/s10393-019-01433-3","article-title":"A transdisciplinary approach to brucella in muskoxen of the western Canadian Arctic 1989\u20132016","volume":"16","author":"M Tomaselli","year":"2019","journal-title":"EcoHealth"},{"key":"pone.0343520.ref069","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.3389\/fmicb.2016.01759","article-title":"Bacterial Genomics Reveal the Complex Epidemiology of an Emerging Pathogen in Arctic and Boreal Ungulates","volume":"7","author":"TL 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