{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T18:45:48Z","timestamp":1775673948702,"version":"3.50.1"},"reference-count":39,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"crossref","award":["(PJT-162348, PJT-175006)"],"award-info":[{"award-number":["(PJT-162348, PJT-175006)"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"crossref","award":["(CBR-170103)"],"award-info":[{"award-number":["(CBR-170103)"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"crossref","award":["Women\u2019s Health and Mentorship grant (F19-05017)"],"award-info":[{"award-number":["Women\u2019s Health and Mentorship grant (F19-05017)"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"crossref","award":["(CTN 335)"],"award-info":[{"award-number":["(CTN 335)"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"crossref","award":["(CTNPT046, CTNPT050)"],"award-info":[{"award-number":["(CTNPT046, CTNPT050)"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"name":"UBC Partner Recognition Fund"},{"name":"UBC Community University Engagement Support Fund"},{"name":"UBC Public Scholar Initiative"},{"name":"Simon Fraser University\u00e2\u20ac\u2122s Community Engagement Initiative"},{"DOI":"10.13039\/501100000245","name":"Michael Smith Foundation of Health Research","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000245","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Canada Research Chair Program"},{"name":"Michael Smith Foundation of Health Research Health Professional investigator award"},{"name":"UBC Four Year Doctoral Fellowship"},{"name":"UBC Centre for Blood Research, and Mitacs Globalink Graduate Fellowship"},{"name":"UBC Edwin S.H. Leong Centre for Healthy Aging"},{"name":"UBC Edwin S.H. Leong Centre for Healthy Aging"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the concordance between self-reported and clinically assessed prevalence of selected chronic conditions and latent viral infections among women living with and without HIV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Women (aged\u2009\u2265\u200916 years residing in British Columbia) enrolled in the BCC3 Study, a prospective cohort, between 2020 and 2024 were included in the cross-sectional analysis. Self-reported prevalence of six conditions\/viruses (chronic kidney disease, liver disease, depression, post-traumatic stress disorder, and hepatitis B and C viruses (HBV, HCV)), were compared to clinical estimates based on screening tools and serology. Agreement was assessed via Cohen\u2019s kappa.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In both women with (n\u2009=\u2009220) and without HIV (n\u2009=\u2009309), clinical estimate-based prevalence of depression and PTSD was higher than self-reported prevalence (all p\u2009&lt;\u20090.001). Among women with HIV, clinical estimate-based prevalence of HBV was higher than self-report-based prevalence (p\u2009&lt;\u20090.001). For both groups, there was no difference between the two prevalence estimates for chronic kidney disease. Among women without HIV, clinical estimate-based prevalence of liver disease was lower than self-report-based prevalence (p\u2009&lt;\u20090.001), but this was not the case for women with HIV. In both groups, agreement between self-report and clinical estimate of prevalence was fair to poor for all conditions\/viruses (all \u03ba\u2009&lt;\u20090.4), except for HCV, for which the agreement was near perfect (\u03ba\u2009&gt;\u20090.8).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Self-reported HCV history shows high concordance with serology, but the same is not true for HBV. The prevalence of liver disease, kidney disease, depression, and post-traumatic stress disorder as reported by participants may differ from clinical estimates. Our findings highlight the complexity of aligning self-report data with clinical estimates and suggest that both types of data should be used for a comprehensive assessment of prevalence in research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0346489","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T17:35:19Z","timestamp":1775669719000},"page":"e0346489","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Concordance between self-report and six commonly used clinical estimates or serological measures: Insights from a Canadian healthy aging study"],"prefix":"10.1371","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-2149-564X","authenticated-orcid":true,"given":"Tovan","family":"Lew","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetiana","family":"Povshedna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth M.","family":"King","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shelly","family":"Tognazzini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Kaida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie C. M.","family":"Murray","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0399-5141","authenticated-orcid":true,"given":"H\u00e9l\u00e8ne C. F.","family":"C\u00f4t\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the British Columbia CARMA-CHIWOS Collaboration (BCC3; CIHR CTN 335)","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2026,4,8]]},"reference":[{"key":"pone.0346489.ref001","unstructured":"UNAIDS. Global HIV statistics fact sheet. 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