{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T18:07:49Z","timestamp":1779386869445,"version":"3.53.1"},"reference-count":35,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"GSK","award":["221264"],"award-info":[{"award-number":["221264"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Despite substantial evidence supporting the benefits of vaccination across all age groups, achieving high vaccine coverage in adults remains a global challenge. Limited disease knowledge and vaccine hesitancy contribute to this issue. To increase vaccination rates, we need to understand the gaps in knowledge, attitudes, and practices (KAP) among adults and healthcare professionals (HCPs). Our primary objectives were to describe the KAP regarding vaccine-preventable diseases and vaccination among adults and HCPs in Mexico, and to identify differences by sociodemographic factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted an observational cross-sectional survey study in three states in Mexico from July to October 2024. Two surveys were administered to adults aged \u226520 years and HCPs to capture outcomes of general vaccine and disease KAP, particularly for vaccine-preventable diseases such as herpes zoster (HZ), influenza, whooping cough, and respiratory syncytial virus (RSV).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 1,169 adults from the general population and 228 HCPs were included. Among the population group, 95.6% acknowledged the importance of vaccines, and 87.6% knew adults could receive routine vaccines. Knowledge of vaccine-preventable diseases ranged from high for influenza (97.3%) to limited for RSV (16.1%) and HZ (39.4%). Fewer knew about RSV (10.1%) and HZ (18.6%) vaccines.<\/jats:p>\n                    <jats:p>Only 23.5% of HCPs had recommended the HZ vaccine to older adults, while more did so for whooping cough (52.2%), influenza (96%). The main factors for HCPs to accept and recommend vaccinations were knowledge of the disease, complications, and vaccine efficacy and effectiveness. Also, 69.8% indicated that information about the disease was the most critical factor in vaccination recommendations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings underscore the need to strengthen health communication and education, and address barriers that impede access to vaccination, particularly for less well-known vaccines. Bridging the gaps between KAP is essential to improving adult vaccination coverage, thereby reducing vaccine-preventable diseases and enhancing public health.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0348625","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T17:25:00Z","timestamp":1779384300000},"page":"e0348625","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Knowledge, attitudes, and practices related to adult vaccination among adults and healthcare professionals across Mexico"],"prefix":"10.1371","volume":"21","author":[{"given":"Erika","family":"Hurtado-Salgado","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Lazcano-Ponce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mart\u00edn","family":"Romero-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Efrain Alonso","family":"Terrazas-Medina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salma","family":"Pacheco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6753-2541","authenticated-orcid":true,"given":"Adriana","family":"Guzman-Holst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,5,21]]},"reference":[{"key":"pone.0348625.ref001","article-title":"The immunization Agenda 2030: a vision of global impact, reaching all, grounded in the realities of a changing world","volume":"42","author":"KL O\u2019Brien","year":"2024","journal-title":"Vaccine"},{"key":"pone.0348625.ref002","unstructured":"World Health Organization. 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Available from: https:\/\/www.who.int\/news-room\/spotlight\/ten-threats-to-global-health-in-2019\/"},{"issue":"10","key":"pone.0348625.ref003","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1080\/14760584.2018.1527690","article-title":"Life-course immunization as a gateway to health","volume":"17","author":"RK Philip","year":"2018","journal-title":"Expert Rev Vaccines"},{"key":"pone.0348625.ref004","volume-title":"Call to action: Strategies to improve adult immunization in the US","author":"National Foundation for Infectious Diseases","year":"2024"},{"issue":"7","key":"pone.0348625.ref005","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.3390\/vaccines11071274","article-title":"Use of information and communication technology strategies to increase vaccination coverage in older adults: a systematic review","volume":"11","author":"A Buja","year":"2023","journal-title":"Vaccines (Basel)"},{"key":"pone.0348625.ref006","article-title":"Immunization agenda 2030: A global strategy to leave no one behind","volume":"42","author":"Immunization Agenda 2030 Partners","year":"2024","journal-title":"Vaccine"},{"key":"pone.0348625.ref007","unstructured":"Ministry of Health. National vaccination cards; 2024 [cited 2025 Jul 7]. Available from: https:\/\/www.gob.mx\/salud\/documentos\/cartillas-nacionales-de-vacunacion"},{"key":"pone.0348625.ref008","doi-asserted-by":"crossref","DOI":"10.21149\/14786","article-title":"Vacunaci\u00f3n en adultos y adultos mayores en M\u00e9xico","volume":"65","author":"N Mongua-Rodr\u00edguez","year":"2023","journal-title":"Salud Publica Mex"},{"key":"pone.0348625.ref009","doi-asserted-by":"crossref","first-page":"2572","DOI":"10.1016\/j.vaccine.2023.03.008","article-title":"Prevalence of influenza-specific vaccination hesitancy among adults in the United States, 2018","volume":"41","author":"A Srivastav","year":"2023","journal-title":"Vaccine"},{"key":"pone.0348625.ref010","volume-title":"State of vaccine confidence in the European Union","author":"A de Figueiredo","year":"2022"},{"issue":"3","key":"pone.0348625.ref011","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.vaccine.2019.10.088","article-title":"Barriers to vaccination in Latin America: a systematic 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Shafie","year":"2023","journal-title":"Vaccines (Basel)"},{"key":"pone.0348625.ref018","article-title":"Pregnant women\u2019s perspectives about maternal immunization in Latin America","author":"A Fauzia Malik","year":"2021","journal-title":"Vaccine"},{"issue":"1","key":"pone.0348625.ref019","doi-asserted-by":"crossref","first-page":"2025007","DOI":"10.1080\/21645515.2021.2025007","article-title":"Knowledge, attitudes, beliefs and barriers of healthcare professionals and adults \u2265 65 years about vaccine-preventable diseases in Spain: the ADult Vaccination drIverS and barriErs (ADVISE) study","volume":"18","author":"E Redondo Marg\u00fcello","year":"2022","journal-title":"Hum Vaccin Immunother"},{"key":"pone.0348625.ref020","doi-asserted-by":"crossref","DOI":"10.3390\/vaccines12010080","article-title":"Exploring perceptions and practices regarding adult vaccination against seasonal influenza, tetanus, pneumococcal disease, herpes zoster and COVID-19: a mixed-methods study in 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