{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T18:05:55Z","timestamp":1783965955958,"version":"3.55.0"},"reference-count":36,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"The Innovation and Entrepreneurship Training Program of Soochow University","award":["2024C029"],"award-info":[{"award-number":["2024C029"]}]},{"name":"Suzhou University School of Nursing","award":["2024HLBK02"],"award-info":[{"award-number":["2024HLBK02"]}]},{"name":"Suzhou Science and Technology Bureau","award":["SKY2023124"],"award-info":[{"award-number":["SKY2023124"]}]},{"DOI":"10.13039\/501100007824","name":"Soochow University","doi-asserted-by":"publisher","award":["ZYQH-2026-15"],"award-info":[{"award-number":["ZYQH-2026-15"]}],"id":[{"id":"10.13039\/501100007824","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>College students often present a sedentary lifestyle. Low-intensity walking training with blood flow restriction (WT-BFR) may offer health benefits comparable to moderate-to-high intensity walking training without restriction, yet its effects in sedentary college students remain unclear. This study aimed to examine the effects of WT-BFR at different limb occlusion pressure (LOP) on hemodynamic and perceptual responses in sedentary college students using a randomized crossover design. The study was registered on the China Clinical Trial Registry (ChiCTR2500097728 25\/02\/2025). A total of 60 participants completed the 5-minute WT-BFR with varying LOPs (i.e., 0%, 40%, 60%, and 80%). Hemodynamic parameters (blood pressure and heart rate) were measured before, immediately after, and 5 minutes post-intervention. Meanwhile, perceptual responses (perceived exertion and discomfort) and step numbers were recorded post-intervention. For the hemodynamic parameters, only 60% LOP showed a larger increase in heart rate after training than 0% LOP (walk training without BFR) condition (3.82, 95%CI: 0.72 to 6.91, p\u2009=\u20090.016, beats\/min), representing a relative increase of approximately 5.6% from baseline. With the increase of LOP, perceived exertion and discomfort were increased significantly (p\u2009&lt;\u20090.05), and the step numbers were reduced (p\u2009&lt;\u20090.05). Based on participant perception, an LOP range of 40%\u201360% is recommended. Clinically, the observed cardiovascular changes were modest and within safe ranges for healthy young adults. The long-term health effects of low-intensity WT-BFR among college students warrant further investigation.<\/jats:p>","DOI":"10.1371\/journal.pone.0352582","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T17:31:47Z","timestamp":1783963907000},"page":"e0352582","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of walking training with blood flow restriction on the hemodynamics and perceptual responses among sedentary college students: A randomized crossover 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