{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T18:04:21Z","timestamp":1784225061123,"version":"3.55.0"},"reference-count":51,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>Discrepancies in factors influencing low-density lipoprotein cholesterol (LDL-C) control in patients with myocardial infarction have been documented in existing literature. Assessing LDL-C control and the associated factors is a crucial initial measure for guiding future interventions aimed at enhancing health outcomes in patients with myocardial infarction (MI). This study aimed to evaluate LDL-C control status and explore the predictors of uncontrolled LDL-C in patients with myocardial infarction. Data were collected by a research pharmacist from medical records, including sociodemographic and clinical characteristics, comorbidities, prescribed medications, and biomedical parameters such as LDL-C levels among patients attending an outpatient cardiology clinic. The validated Arabic versions of the 4-item medication adherence scale and the medication beliefs questionnaire were used to evaluate medication adherence and beliefs, respectively. Binary logistic regression was implemented to investigate the predictors of LDL-C control. The results showed most of the patients (n\u2009=\u2009255) had uncontrolled LDL-C (76.6%). Regression results revealed that smoking (OR= 2.006; 95% CI: 1.054\u20133.816; P\u2009=\u20090.034), receiving beta blockers (OR=2.211; 95% CI: 1.024\u20134.775; P\u2009=\u20090.043), and having uncontrolled blood pressure (OR=1.940; 95% CI: 1.069\u20133.520; P\u2009=\u20090.029) were independently associated with higher odds of uncontrolled LDL-C. In conclusion, in MI patients with poor LDL-C control, lowering the risk of cardiac complications and improving health outcomes require the development of focused and efficient LDL-C level management strategies. Achieving this goal will require putting strategies like smoking cessation counselling into practice and improving BP control.<\/jats:p>","DOI":"10.1371\/journal.pone.0353521","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T17:25:26Z","timestamp":1784222726000},"page":"e0353521","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Factors associated with low-density lipoprotein control in outpatients with myocardial infarction: A hospital-based study"],"prefix":"10.1371","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0416-506X","authenticated-orcid":true,"given":"Anan S.","family":"Jarab","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walid","family":"Al-Qerem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Razan","family":"Mansour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamza","family":"Jarab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shrouq R.","family":"Abu Heshmeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0173-9679","authenticated-orcid":true,"given":"Omar","family":"Jrab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"Elrefae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3984-3542","authenticated-orcid":true,"given":"Yazid N.","family":"Al Hamarneh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad Z.","family":"Al Meslamani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2478-3914","authenticated-orcid":true,"given":"Salahdein","family":"Aburuz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,7,16]]},"reference":[{"issue":"2","key":"pone.0353521.ref001","doi-asserted-by":"crossref","first-page":"195","DOI":"10.5603\/CJ.a2021.0036","article-title":"Fourth universal definition of myocardial infarction. 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