{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:24:14Z","timestamp":1786991054421,"version":"build-2736575974"},"reference-count":54,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009238","name":"Virginia Commonwealth University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009238","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009238","name":"Virginia Commonwealth University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009238","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009238","name":"Virginia Commonwealth University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009238","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Persistent autonomic dysfunction disrupts homeostasis and promotes pathological processes underlying several major chronic conditions including cancer and cardiovascular disease. Little is known about the lived experience of individuals living with conditions marked by autonomic dysfunction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To understand the lived experiences and perspectives of individuals with conditions characterized by autonomic dysfunction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A mixed method, cross sectional study was conducted with individuals (n\u2009=\u2009489) with conditions marked by autonomic dysfunction, with a focus on recruiting from marginalized populations\n                      <jats:bold>.<\/jats:bold>\n                      Participants completed a survey exploring symptoms and experiences with seeking and receiving care for conditions and symptoms marked by autonomic dysfunction. A subset of 45 participants also completed semi-structured interviews.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>At the healthcare system level, participants were concerned about provider availability and a lack of support for patients and providers. At the provider level, participants had negative experiences with dismissive providers and positive experiences when providers believed patients. At the patient level, patients reported that anxiety, depression, sleep problems, brain fog, and fatigue were their most common symptoms, and that they often reduced work hours or stopped working. Patients described using their own research more often than provider recommendations to seek wellness treatments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec005\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The lived experience for people with autonomic dysfunction is multilayered, includes the patient\u2019s personal experience, and is influenced by the patient-provider relationship embedded in unsupportive healthcare systems. These experiences may reinforce the physiological dysregulation at the core of many condition and symptoms, potentially exacerbating a feedback loop of distress, invalidation, mistrust, avoidance, and increased vulnerability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0355952","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:24:27Z","timestamp":1786987467000},"page":"e0355952","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lived experiences and perspectives of persons with conditions marked by autonomic dysfunction"],"prefix":"10.1371","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0671-3178","authenticated-orcid":true,"given":"Lisa L.","family":"Shah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9319-8922","authenticated-orcid":true,"given":"Patricia A.","family":"Kinser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Moyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Rider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Decker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominik","family":"Feliciano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6851-8185","authenticated-orcid":true,"given":"Leslie","family":"Lantz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taylor B.","family":"Crouch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elliot","family":"Popoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lathika","family":"Mohanraj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2917-9804","authenticated-orcid":true,"given":"Joshua W.","family":"Hahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Bo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron","family":"Gharbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisela","family":"Chelimsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Burch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy L.","family":"Salisbury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Chelimsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,8,17]]},"reference":[{"key":"pone.0355952.ref001","doi-asserted-by":"crossref","first-page":"712823","DOI":"10.3389\/fpsyg.2021.712823","article-title":"Can Exercise Reduce the Autonomic Dysfunction of Patients With Cancer and Its Survivors? 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Application to patients with multiple sclerosis and systemic lupus erythematosus","volume":"46","author":"LB Krupp","year":"1989","journal-title":"Arch Neurol"},{"issue":"4","key":"pone.0355952.ref025","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1002\/1098-240X(200008)23:4<334::AID-NUR9>3.0.CO;2-G","article-title":"Whatever happened to qualitative description?","volume":"23","author":"M Sandelowski","year":"2000","journal-title":"Res Nurs Health"},{"issue":"3","key":"pone.0355952.ref026","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1080\/17439760.2016.1262613","article-title":"Thematic analysis","volume":"12","author":"V Clarke","year":"2017","journal-title":"J Posit Psychol"},{"key":"pone.0355952.ref027","doi-asserted-by":"crossref","DOI":"10.1016\/0147-1767(85)90062-8","volume-title":"Naturalistic Inquiry","author":"YS Lincoln","year":"1985"},{"issue":"6","key":"pone.0355952.ref028","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1093\/intqhc\/mzm042","article-title":"Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups","volume":"19","author":"A Tong","year":"2007","journal-title":"Int J Qual Health Care"},{"issue":"7","key":"pone.0355952.ref029","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1037\/0003-066X.32.7.513","article-title":"Toward an experimental ecology of human development","volume":"32","author":"U Bronfenbrenner","year":"1977","journal-title":"Am Psychol"},{"issue":"4","key":"pone.0355952.ref030","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1177\/109019818801500401","article-title":"An ecological perspective on health promotion programs","volume":"15","author":"KR McLeroy","year":"1988","journal-title":"Health Educ Q"},{"issue":"4","key":"pone.0355952.ref031","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1037\/bul0000473","article-title":"Ignored, dismissed, and minimized: Understanding the harmful consequences of invalidation in health care-A systematic meta-synthesis of qualitative research","volume":"151","author":"AC Bontempo","year":"2025","journal-title":"Psychol Bull"},{"key":"pone.0355952.ref032","article-title":"\u201cYou have to trust yourself\u201d: The Overlooked Role of Self-Trust in Coping with Chronic Illness","author":"R Grob","year":"2023","journal-title":"Hastings Cent Rep"},{"issue":"5","key":"pone.0355952.ref033","article-title":"Medical invalidation in the clinical encounter: a qualitative study of the health care experiences of young women and nonbinary people living with chronic illnesses","volume":"11","author":"JCH Sebring","year":"2023","journal-title":"CMAJ Open"},{"issue":"9","key":"pone.0355952.ref034","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1037\/hea0000368","article-title":"African American experiences in healthcare: \u201cI always feel like I\u2019m getting skipped over\u201d","volume":"35","author":"AG Cuevas","year":"2016","journal-title":"Health Psychol"},{"key":"pone.0355952.ref035","doi-asserted-by":"crossref","first-page":"23743735251314651","DOI":"10.1177\/23743735251314651","article-title":"The Diagnostic Journey of Dysautonomia Patients: Insights from a Patient-Reported Outcome Study","volume":"12","author":"JA O\u2019Dell","year":"2025","journal-title":"J Patient Exp"},{"key":"pone.0355952.ref036","doi-asserted-by":"crossref","first-page":"73","DOI":"10.21037\/tgh-24-26","article-title":"We didn\u2019t start the fire\u2026or did we?-a narrative review of medical gaslighting and introduction to medical invalidation","volume":"9","author":"A Fuss","year":"2024","journal-title":"Transl Gastroenterol Hepatol"},{"issue":"2","key":"pone.0355952.ref037","doi-asserted-by":"crossref","first-page":"275","DOI":"10.3390\/ijerph22020275","article-title":"Language Matters: What Not to Say to Patients with Long COVID, Myalgic Encephalomyelitis\/Chronic Fatigue Syndrome, and Other Complex Chronic Disorders","volume":"22","author":"NJ Smyth","year":"2025","journal-title":"Int J Environ Res Public Health"},{"issue":"2","key":"pone.0355952.ref038","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1177\/10497323241253418","article-title":"Conceptualizing Symptom Invalidation as Experienced by Patients With Endometriosis","volume":"35","author":"AC Bontempo","year":"2025","journal-title":"Qual Health Res"},{"issue":"8","key":"pone.0355952.ref039","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1097\/j.pain.0000000000000512","article-title":"Understanding stigma and chronic pain: a-state-of-the-art review","volume":"157","author":"L De Ruddere","year":"2016","journal-title":"Pain"},{"issue":"6","key":"pone.0355952.ref040","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1016\/j.pec.2021.09.034","article-title":"The effect of personalized invalidation of symptoms by healthcare providers on patient depression: The mediating role of self-esteem","volume":"105","author":"AC Bontempo","year":"2022","journal-title":"Patient Educ Couns"},{"key":"pone.0355952.ref041","doi-asserted-by":"crossref","first-page":"104986","DOI":"10.1016\/j.ijnurstu.2024.104986","article-title":"Understanding the experiences of people who have Postural Orthostatic Tachycardia Syndrome (POTS) and the health professionals who care for them: A grounded theory study","volume":"164","author":"H Eftekhari","year":"2025","journal-title":"Int J Nurs Stud"},{"issue":"7","key":"pone.0355952.ref042","first-page":"491","article-title":"Family physicians and health advocacy: Is it really a difficult fit?","volume":"65","author":"C Bernard","year":"2019","journal-title":"Can Fam Physician"},{"issue":"4","key":"pone.0355952.ref043","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1007\/s10912-021-09690-6","article-title":"Voices from the Front Lines: An Analysis of Physicians\u2019 Reflective Narratives about Flaws with the \u201cSystem\u201d","volume":"42","author":"T Moniz","year":"2021","journal-title":"J Med Humanit"},{"key":"pone.0355952.ref044","unstructured":"National Academies of Sciences Engineering and Medicine; National Academy of Medicine; Committee on Systems Approaches to Improve Patient Care by Supporting Clinician Well-Being, E. Taking action against clinician burnout: A systems approach to professional well-being. Washington, D.C: National Academies Press; 2019."},{"issue":"6","key":"pone.0355952.ref045","article-title":"Interprofessional collaboration to improve professional practice and healthcare outcomes","volume":"6","author":"S Reeves","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"issue":"6","key":"pone.0355952.ref046","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1177\/00099228221141602","article-title":"\u201cYou Look Perfectly Healthy to Me\u201d: Living With Postural Orthostatic Tachycardia Syndrome Through Adolescents\u2019 and Parents\u2019 Eyes","volume":"62","author":"WS Frye","year":"2023","journal-title":"Clin Pediatr (Phila)"},{"issue":"8","key":"pone.0355952.ref047","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/j.mayocp.2012.02.020","article-title":"A prospective, 1-year follow-up study of postural tachycardia syndrome","volume":"87","author":"K Kimpinski","year":"2012","journal-title":"Mayo Clin Proc"},{"key":"pone.0355952.ref048","doi-asserted-by":"crossref","first-page":"1052137","DOI":"10.3389\/fneur.2022.1052137","article-title":"The grand challenge of autonomic disorders","volume":"13","author":"WP Cheshire","year":"2022","journal-title":"Front Neurol"},{"issue":"1","key":"pone.0355952.ref049","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/s41746-026-02543-3","article-title":"Digital physiological biomarkers predict within-person symptom changes in complex chronic illness","volume":"9","author":"A Aitken","year":"2026","journal-title":"NPJ Digit Med"},{"key":"pone.0355952.ref050","doi-asserted-by":"crossref","first-page":"582145","DOI":"10.3389\/fnins.2020.582145","article-title":"The Role of Heart Rate Variability in the Future of Remote Digital Biomarkers","volume":"14","author":"AP Owens","year":"2020","journal-title":"Front Neurosci"},{"issue":"4","key":"pone.0355952.ref051","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.pmr.2020.07.003","article-title":"Autonomic Rehabilitation: Adapting to Change","volume":"31","author":"RS Gharbo","year":"2020","journal-title":"Phys Med Rehabil Clin N Am"},{"issue":"5","key":"pone.0355952.ref052","doi-asserted-by":"crossref","DOI":"10.1088\/1361-6579\/aabf64","article-title":"A review of physiological and behavioral monitoring with digital sensors for neuropsychiatric illnesses","volume":"39","author":"E Reinertsen","year":"2018","journal-title":"Physiol Meas"},{"issue":"1","key":"pone.0355952.ref053","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s12026-025-09661-2","article-title":"Dysautonomia: A common comorbidity of systemic disease","volume":"73","author":"S Blitshteyn","year":"2025","journal-title":"Immunol Res"},{"issue":"1","key":"pone.0355952.ref054","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s10286-020-00749-3","article-title":"\u201cDysautonomia\u201d: a plea for precision","volume":"31","author":"EE Benarroch","year":"2021","journal-title":"Clin Auton Res"}],"container-title":["PLOS One"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0355952","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:24:35Z","timestamp":1786987475000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0355952"}},"subtitle":[],"editor":[{"given":"Tanja","family":"Grubi\u0107 Kezele","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,8,17]]},"references-count":54,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2026,8,17]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0355952","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,17]]}}}